IE39587L - Antibacterial composition - Google Patents

Antibacterial composition

Info

Publication number
IE39587L
IE39587L IE741408A IE140874A IE39587L IE 39587 L IE39587 L IE 39587L IE 741408 A IE741408 A IE 741408A IE 140874 A IE140874 A IE 140874A IE 39587 L IE39587 L IE 39587L
Authority
IE
Ireland
Prior art keywords
fluoro
alanine
hydrogen
acceptable salt
antibacterial composition
Prior art date
Application number
IE741408A
Other versions
IE39587B1 (en
Inventor
Frederick M Kahan
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE39587L publication Critical patent/IE39587L/en
Publication of IE39587B1 publication Critical patent/IE39587B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1457950 Antibacterial compositions MERCK & CO INC 22 July 1974 [10 Aug 1973 13 June 1974] 32360/74 Addition to 1421023 Heading A5B [Also in Division C2] Antibacterial compositions comprise as active ingredients a mixture of 3-fluoro-D-alanine, 2-deutero-3-fluoro-D-alanine, 2, 3-dideutero-3- fluoro-D-alanine, 2, 3, 3-trideutero-3-fluoro-D- alinine, a C 1-5 alkyl ester thereof or a pharmaceutically acceptable salt thereof, with a 3- fluoro-D-alanine. autoantagonist-inhibitor comprising an isoxazolidinone compound of formula in which R is hydrogen or methyl, and each of X, Y and Z is hydrogen or alkyl, or a pharmacologically acceptable salt thereof. The compositions may be administered orally or parenterally in the form of capsules, tablets, solutions or suspensions. [GB1457950A]
IE1408/74A 1973-08-10 1974-07-03 Antibacterial compositions IE39587B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38757173A 1973-08-10 1973-08-10
US47879374A 1974-06-13 1974-06-13

Publications (2)

Publication Number Publication Date
IE39587L true IE39587L (en) 1975-02-10
IE39587B1 IE39587B1 (en) 1978-11-08

Family

ID=27011935

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1408/74A IE39587B1 (en) 1973-08-10 1974-07-03 Antibacterial compositions

Country Status (11)

Country Link
CA (1) CA1039191A (en)
CY (1) CY1054A (en)
DE (1) DE2436959C2 (en)
FR (1) FR2240000B2 (en)
GB (1) GB1457950A (en)
HK (1) HK23280A (en)
IE (1) IE39587B1 (en)
IL (1) IL45174A (en)
KE (1) KE3042A (en)
MY (1) MY8100050A (en)
NL (1) NL181407C (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4034713A1 (en) * 1990-11-01 1992-05-07 Bayer Ag 3-OXY-SUBSTITUTED ISOXAZOLINES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR THE CONTROL OF ENDOPARASITES
AU2436600A (en) * 1999-01-13 2000-08-01 Jomaa Pharmaka Gmbh Use of 3-isoxazolidinones and hydroxylamine acids for the treatment of infections

Also Published As

Publication number Publication date
CA1039191A (en) 1978-09-26
CY1054A (en) 1980-08-01
GB1457950A (en) 1976-12-08
NL7409574A (en) 1975-02-12
DE2436959A1 (en) 1975-02-20
HK23280A (en) 1980-05-09
IE39587B1 (en) 1978-11-08
FR2240000B2 (en) 1977-10-28
AU7125074A (en) 1976-01-15
NL181407C (en) 1987-08-17
DE2436959C2 (en) 1987-03-05
KE3042A (en) 1980-05-09
FR2240000A2 (en) 1975-03-07
MY8100050A (en) 1981-12-31
IL45174A (en) 1976-12-31

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