ITRM920028A0 - Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. - Google Patents
Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.Info
- Publication number
- ITRM920028A0 ITRM920028A0 IT92RM28A ITRM920028A ITRM920028A0 IT RM920028 A0 ITRM920028 A0 IT RM920028A0 IT 92RM28 A IT92RM28 A IT 92RM28A IT RM920028 A ITRM920028 A IT RM920028A IT RM920028 A0 ITRM920028 A0 IT RM920028A0
- Authority
- IT
- Italy
- Prior art keywords
- acil
- contain
- long
- pharmaceutical compositions
- aliphatic alcohols
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical class C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
- 150000001298 alcohols Chemical class 0.000 title 1
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM920028A IT1254136B (it) | 1992-01-16 | 1992-01-16 | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. |
ZA93161A ZA93161B (en) | 1992-01-16 | 1993-01-11 | Esters of acyl carnitines with long-chain alpihatic alcohols and pharmaceutical compositions containing same having antibacterial activity |
CA002087084A CA2087084C (en) | 1992-01-16 | 1993-01-11 | Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity |
JP00475793A JP3294652B2 (ja) | 1992-01-16 | 1993-01-14 | アシルカルニチンエステル類および抗真菌活性医薬組成物 |
DE69309725T DE69309725T2 (de) | 1992-01-16 | 1993-01-15 | Verwendung von Estern des Acyl-Carnitins mit langkettigen aliphatischen Alkoholen zur Herstellung von pharmazeutischen Zusammensetzungen mit antimykotischer Wirkung |
DK93830010.0T DK0552138T3 (da) | 1992-01-16 | 1993-01-15 | Anvendelse af estere af acylcarnitiner med langkædede alifatiske alkoholer til fremstilling af farmaceutiske præparater med antimykotisk aktivitet. |
ES93830010T ES2101998T3 (es) | 1992-01-16 | 1993-01-15 | Uso de esteres de acilcarnitinas con alcoholes alifaticos de cadena larga para la preparacion de composiciones farmaceuticas con actividad antimicotica. |
EP93830010A EP0552138B1 (en) | 1992-01-16 | 1993-01-15 | Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity |
AT93830010T ATE151744T1 (de) | 1992-01-16 | 1993-01-15 | Verwendung von estern des acyl-carnitins mit langkettigen aliphatischen alkoholen zur herstellung von pharmazeutischen zusammensetzungen mit antimykotischer wirkung |
KR1019930000523A KR100251887B1 (ko) | 1992-01-16 | 1993-01-16 | 긴 사슬의 지방족 알콜을 가진 아실카르니틴 에스테르와 항진균 활성을 지닌 그의 약제조성물 |
US08/250,108 US5519056A (en) | 1992-01-16 | 1994-05-26 | Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity |
US08/409,714 US5525627A (en) | 1992-01-16 | 1995-03-24 | Esters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antimycotic activity |
GR960403681T GR3023163T3 (en) | 1992-01-16 | 1997-04-17 | Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity |
HK98104939A HK1005864A1 (en) | 1992-01-16 | 1998-06-05 | Use of esters of acyl carnitines with long-chain aliphatic alcohols in the preparation of pharmaceutical compositions having antimycotic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM920028A IT1254136B (it) | 1992-01-16 | 1992-01-16 | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM920028A0 true ITRM920028A0 (it) | 1992-01-16 |
ITRM920028A1 ITRM920028A1 (it) | 1993-07-16 |
IT1254136B IT1254136B (it) | 1995-09-08 |
Family
ID=11400574
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM920028A IT1254136B (it) | 1992-01-16 | 1992-01-16 | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5519056A (it) |
EP (1) | EP0552138B1 (it) |
JP (1) | JP3294652B2 (it) |
KR (1) | KR100251887B1 (it) |
AT (1) | ATE151744T1 (it) |
CA (1) | CA2087084C (it) |
DE (1) | DE69309725T2 (it) |
DK (1) | DK0552138T3 (it) |
ES (1) | ES2101998T3 (it) |
GR (1) | GR3023163T3 (it) |
HK (1) | HK1005864A1 (it) |
IT (1) | IT1254136B (it) |
ZA (1) | ZA93161B (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1258370B (it) * | 1992-03-02 | 1996-02-26 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil l-carnitine dotati di attivita' miorilassante selettiva sull'apparato gastro-intestinale e composizioni farmaceutiche che li contengono. |
IT1261828B (it) | 1993-07-14 | 1996-06-03 | Sigma Tau Ind Farmaceuti | Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico. |
US5741816A (en) | 1994-06-20 | 1998-04-21 | Tanabe Seiyaku Co., Ltd. | Hair-growth agent |
IT1277898B1 (it) * | 1995-08-03 | 1997-11-12 | Mendes Srl | Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie |
IT1283955B1 (it) * | 1996-03-20 | 1998-05-07 | Sigma Tau Ind Farmaceuti | Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria. |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH596147A5 (it) * | 1974-09-25 | 1978-02-28 | Lonza Ag | |
CH588443A5 (it) * | 1974-09-25 | 1977-06-15 | Lonza Ag | |
IT1116037B (it) * | 1979-04-23 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico |
IT1147079B (it) * | 1980-05-30 | 1986-11-19 | Sigma Tau Ind Farmacuetiche Ri | Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono |
IT1170861B (it) * | 1981-03-31 | 1987-06-03 | Sigma Tau Ind Farmaceuti | Ester di mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico |
IT1191945B (it) * | 1986-06-04 | 1988-03-31 | Avantgarde Spa | N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono |
IT1235494B (it) * | 1987-12-02 | 1992-09-04 | Avantgarde Spa | N-alchilammidi della dl e l(-)carnitina dotate di attivita' antibatterica, procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono |
IT1231751B (it) * | 1989-04-12 | 1991-12-21 | Sigma Tau Ind Farmaceuti | Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina |
IT1231944B (it) * | 1989-05-05 | 1992-01-16 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina |
IT1240775B (it) * | 1990-02-23 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma. |
-
1992
- 1992-01-16 IT ITRM920028A patent/IT1254136B/it active
-
1993
- 1993-01-11 ZA ZA93161A patent/ZA93161B/xx unknown
- 1993-01-11 CA CA002087084A patent/CA2087084C/en not_active Expired - Fee Related
- 1993-01-14 JP JP00475793A patent/JP3294652B2/ja not_active Expired - Fee Related
- 1993-01-15 DK DK93830010.0T patent/DK0552138T3/da active
- 1993-01-15 AT AT93830010T patent/ATE151744T1/de not_active IP Right Cessation
- 1993-01-15 ES ES93830010T patent/ES2101998T3/es not_active Expired - Lifetime
- 1993-01-15 EP EP93830010A patent/EP0552138B1/en not_active Expired - Lifetime
- 1993-01-15 DE DE69309725T patent/DE69309725T2/de not_active Expired - Lifetime
- 1993-01-16 KR KR1019930000523A patent/KR100251887B1/ko not_active IP Right Cessation
-
1994
- 1994-05-26 US US08/250,108 patent/US5519056A/en not_active Expired - Lifetime
-
1995
- 1995-03-24 US US08/409,714 patent/US5525627A/en not_active Expired - Lifetime
-
1997
- 1997-04-17 GR GR960403681T patent/GR3023163T3/el unknown
-
1998
- 1998-06-05 HK HK98104939A patent/HK1005864A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR930016392A (ko) | 1993-08-26 |
GR3023163T3 (en) | 1997-07-30 |
EP0552138A3 (en) | 1993-10-20 |
ZA93161B (en) | 1993-10-06 |
EP0552138B1 (en) | 1997-04-16 |
CA2087084C (en) | 2003-12-23 |
CA2087084A1 (en) | 1993-07-17 |
HK1005864A1 (en) | 1999-01-29 |
EP0552138A2 (en) | 1993-07-21 |
US5525627A (en) | 1996-06-11 |
DE69309725T2 (de) | 1997-07-31 |
US5519056A (en) | 1996-05-21 |
ITRM920028A1 (it) | 1993-07-16 |
JP3294652B2 (ja) | 2002-06-24 |
ES2101998T3 (es) | 1997-07-16 |
IT1254136B (it) | 1995-09-08 |
JPH05339219A (ja) | 1993-12-21 |
DK0552138T3 (da) | 1997-10-20 |
DE69309725D1 (de) | 1997-05-22 |
ATE151744T1 (de) | 1997-05-15 |
KR100251887B1 (ko) | 2000-05-01 |
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