HK1001085A1 - Lipophilic oligosaccharide antibiotic salt compositions - Google Patents

Lipophilic oligosaccharide antibiotic salt compositions Download PDF

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Publication number
HK1001085A1
HK1001085A1 HK98100167A HK98100167A HK1001085A1 HK 1001085 A1 HK1001085 A1 HK 1001085A1 HK 98100167 A HK98100167 A HK 98100167A HK 98100167 A HK98100167 A HK 98100167A HK 1001085 A1 HK1001085 A1 HK 1001085A1
Authority
HK
Hong Kong
Prior art keywords
formula
cyclodextrin
hydroxypropyl
pharmaceutically acceptable
amount
Prior art date
Application number
HK98100167A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1001085B (en
Inventor
Patel Mahesh
P. Gullo Vincent
Hare Roberta
Loebenberg David
B. Morton James
H. Miller George
Y. Kwon Heewon
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of HK1001085A1 publication Critical patent/HK1001085A1/en
Publication of HK1001085B publication Critical patent/HK1001085B/en

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
HK98100167.0A 1991-10-16 1998-01-09 Lipophilic oligosaccharide antibiotic salt compositions HK1001085B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77786491A 1991-10-16 1991-10-16
US777864 1991-10-16

Publications (2)

Publication Number Publication Date
HK1001085A1 true HK1001085A1 (en) 1998-05-22
HK1001085B HK1001085B (en) 1998-05-22

Family

ID=

Also Published As

Publication number Publication date
SI9200260A (en) 1993-06-30
YU92192A (sr) 1996-01-09
ES2104845T3 (es) 1997-10-16
AU2780692A (en) 1993-05-21
GR3024800T3 (en) 1998-01-30
NO307326B1 (no) 2000-03-20
PL170591B1 (pl) 1997-01-31
JPH06510546A (ja) 1994-11-24
FI941723A7 (fi) 1994-04-14
ATE156019T1 (de) 1997-08-15
HUT75157A (en) 1997-04-28
DE69221252D1 (de) 1997-09-04
AU678344B2 (en) 1997-05-29
YU48722B (sh) 1999-07-28
WO1993007904A1 (en) 1993-04-29
EP0538011B1 (en) 1997-07-30
IL103446A (en) 1997-02-18
DE69221252T2 (de) 1998-01-22
FI941723A0 (fi) 1994-04-14
DK0538011T3 (da) 1997-09-08
NZ244735A (en) 1995-12-21
EP0610295A1 (en) 1994-08-17
HU9401104D0 (en) 1994-07-28
EP0538011A1 (en) 1993-04-21
TW221378B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-03-01
MX9205922A (es) 1994-08-31
NO941276L (no) 1994-04-08
CN1035923C (zh) 1997-09-24
HRP921069B1 (en) 1999-12-31
ZA927923B (en) 1993-04-26
CA2121345A1 (en) 1993-04-29
IL103446A0 (en) 1993-03-15
PH31675A (en) 1999-01-18
CA2121345C (en) 1998-08-25
CN1073359A (zh) 1993-06-23
NO941276D0 (no) 1994-04-08
KR100249584B1 (ko) 2000-04-01
JP2614407B2 (ja) 1997-05-28
HRP921069A2 (en) 1994-12-31
US5624914A (en) 1997-04-29

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)