HK1000209A1 - Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative - Google Patents

Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative

Info

Publication number
HK1000209A1
HK1000209A1 HK97101737A HK97101737A HK1000209A1 HK 1000209 A1 HK1000209 A1 HK 1000209A1 HK 97101737 A HK97101737 A HK 97101737A HK 97101737 A HK97101737 A HK 97101737A HK 1000209 A1 HK1000209 A1 HK 1000209A1
Authority
HK
Hong Kong
Prior art keywords
alpha
aminoacid
keto acid
derivative
alkyl
Prior art date
Application number
HK97101737A
Other languages
English (en)
Inventor
Kottenhahn Matthias
Harr Horst
Drauz Karlheinz
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of HK1000209A1 publication Critical patent/HK1000209A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
HK97101737A 1991-07-13 1997-09-08 Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative HK1000209A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4123248A DE4123248C2 (de) 1991-07-13 1991-07-13 Verfahren zur Herstellung von N-substituierten alpha-Aminosäuren und alpha-Aminosäure-Derivaten

Publications (1)

Publication Number Publication Date
HK1000209A1 true HK1000209A1 (en) 1998-02-06

Family

ID=6436071

Family Applications (1)

Application Number Title Priority Date Filing Date
HK97101737A HK1000209A1 (en) 1991-07-13 1997-09-08 Reductive amination of an aminoacid or an aminoacid derivative with an alpha-keto acid or an alpha-keto acid derivative

Country Status (14)

Country Link
US (1) US5387696A (xx)
EP (1) EP0523449B1 (xx)
JP (1) JP3224422B2 (xx)
AT (1) ATE138075T1 (xx)
CZ (1) CZ286877B6 (xx)
DE (2) DE4123248C2 (xx)
DK (1) DK0523449T3 (xx)
ES (1) ES2052492T3 (xx)
GR (1) GR3020061T3 (xx)
HK (1) HK1000209A1 (xx)
HU (1) HU213524B (xx)
IE (1) IE73437B1 (xx)
SG (1) SG48736A1 (xx)
SK (1) SK283042B6 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1243594B1 (en) * 1993-01-08 2004-05-12 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for crystallizing N2-((S)-1-ethoxycarbonyl-3-phenylpropyl)-N6-trifluoroacetyl-L-lysyl-L-proline
US5319098A (en) * 1993-05-18 1994-06-07 Celgene Corporation Process for the stereoselective preparation of L-alanyl-L-proline
DE4331540A1 (de) * 1993-09-17 1995-03-23 Degussa Verfahren zur Reinigung von 1-[N·2·-((S)-Ethoxycarbonyl)-3-phenylpropyl)-N·6·-trifluoracetyl]-L-lysyl-L-prolin (Lisinopril(Tfa)ethylester)
IT1271687B (it) * 1994-08-04 1997-06-04 Flamma Spa Sali organici idrosolubili della creatina
AU702718B2 (en) * 1995-09-15 1999-03-04 Merck & Co., Inc. Method for analyzing isomers of enalapril and enalaprilat
US5907044A (en) * 1997-07-30 1999-05-25 Degussa Aktiengellschaft Method of isolating 1- N2 -((S)-ethoxycarbonyl)-3-phenylpropyl)-N6 -trifluoroacetyl!-L-lysyl-L-proline (lisinopril (TFA) ethyl ester, LPE)
AR021803A1 (es) * 1998-09-23 2002-08-07 Merck & Co Inc Proceso estereoselectivo perfeccionado para enalapril.
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
AR033048A1 (es) * 2001-03-19 2003-12-03 Kaneka Corp Metodo para la purificacion de la n-(1(s)-etoxicarbonil-3-fenilpropil) -l-alanina
US7074959B2 (en) 2002-08-01 2006-07-11 New Mexico Highlands University Methods and systems for remediating hydrazine-contaminated equipment and/or surfaces
US20080103202A1 (en) * 2004-11-08 2008-05-01 Chris Ferguson Method of preparing creatine ester salts and uses thereof.
WO2008132759A2 (en) * 2007-04-27 2008-11-06 Matrix Laboratories Ltd Industrially advantageous process for the production of lisinopril dihydrate
WO2014043182A2 (en) 2012-09-14 2014-03-20 Bioamber Inc. Alternative pathways to adipates and adipic acid by combined fermentation and catalytic methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU543804B2 (en) * 1980-10-31 1985-05-02 Takeda Chemical Industries Ltd. Amides having bicyclic substituents on nitrogen

Also Published As

Publication number Publication date
IE922274A1 (en) 1993-01-13
EP0523449A2 (de) 1993-01-20
DE59206279D1 (de) 1996-06-20
SK216692A3 (en) 1994-12-07
HU213524B (en) 1997-07-28
JP3224422B2 (ja) 2001-10-29
US5387696A (en) 1995-02-07
ATE138075T1 (de) 1996-06-15
GR3020061T3 (en) 1996-08-31
JPH05201882A (ja) 1993-08-10
SK283042B6 (sk) 2003-02-04
HUT63634A (en) 1993-09-28
SG48736A1 (en) 1998-05-18
EP0523449A3 (en) 1993-09-29
ES2052492T3 (es) 1996-07-16
ES2052492T1 (es) 1994-07-16
CZ216692A3 (en) 1993-02-17
CZ286877B6 (cs) 2000-07-12
DK0523449T3 (da) 1996-07-08
HU9202295D0 (en) 1992-10-28
EP0523449B1 (de) 1996-05-15
DE4123248C2 (de) 1996-03-07
DE4123248A1 (de) 1993-01-14
IE73437B1 (en) 1997-06-04

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)