GT200600211A - Derivados de (sulfamoil-alquil)-amida de acido heteroaril-carboxilico como inhibidores del factor xa - Google Patents
Derivados de (sulfamoil-alquil)-amida de acido heteroaril-carboxilico como inhibidores del factor xaInfo
- Publication number
- GT200600211A GT200600211A GT200600211A GT200600211A GT200600211A GT 200600211 A GT200600211 A GT 200600211A GT 200600211 A GT200600211 A GT 200600211A GT 200600211 A GT200600211 A GT 200600211A GT 200600211 A GT200600211 A GT 200600211A
- Authority
- GT
- Guatemala
- Prior art keywords
- inhibitors
- factor
- sulfamoil
- heteroaril
- alquil
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05010929A EP1724269A1 (en) | 2005-05-20 | 2005-05-20 | Heteroaryl-carboxylic acid (sulfamoyl alkyl) amide - derivatives as factor Xa inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT200600211A true GT200600211A (es) | 2007-02-05 |
Family
ID=35116052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT200600211A GT200600211A (es) | 2005-05-20 | 2006-05-18 | Derivados de (sulfamoil-alquil)-amida de acido heteroaril-carboxilico como inhibidores del factor xa |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8088925B2 (https=) |
| EP (2) | EP1724269A1 (https=) |
| JP (1) | JP5027802B2 (https=) |
| KR (1) | KR101373533B1 (https=) |
| CN (1) | CN101180296B (https=) |
| AR (1) | AR053730A1 (https=) |
| AT (1) | ATE452133T1 (https=) |
| AU (1) | AU2006246669B2 (https=) |
| BR (1) | BRPI0610320A2 (https=) |
| CA (1) | CA2609288C (https=) |
| DE (1) | DE602006011156D1 (https=) |
| DK (1) | DK1888567T3 (https=) |
| DO (1) | DOP2006000119A (https=) |
| ES (1) | ES2338151T3 (https=) |
| GT (1) | GT200600211A (https=) |
| IL (1) | IL187430A (https=) |
| MX (1) | MX2007014274A (https=) |
| MY (1) | MY150693A (https=) |
| PA (1) | PA8675301A1 (https=) |
| PE (1) | PE20061452A1 (https=) |
| PT (1) | PT1888567E (https=) |
| SV (1) | SV2007002534A (https=) |
| TW (1) | TWI376377B (https=) |
| UY (1) | UY29550A1 (https=) |
| WO (1) | WO2006122661A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012149102A1 (en) * | 2011-04-29 | 2012-11-01 | Glaxosmithkline Llc | Novel compounds as wip1 inhibitors |
| EP3078378B1 (en) | 2015-04-08 | 2020-06-24 | Vaiomer | Use of factor xa inhibitors for regulating glycemia |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI9520044B (sl) | 1994-04-26 | 2004-08-31 | Aventis Pharmaceuticals Inc. | Inhibitorji Xa faktorja |
| GB0030305D0 (en) * | 2000-12-13 | 2001-01-24 | Lilly Co Eli | Compounds |
| EP1217000A1 (en) * | 2000-12-23 | 2002-06-26 | Aventis Pharma Deutschland GmbH | Inhibitors of factor Xa and factor VIIa |
| HUP0304058A2 (hu) * | 2001-01-30 | 2004-04-28 | Bristol-Myers Squibb Company | Xa faktor szulfonamid-laktám inhibitorok és alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények |
| DE10254336A1 (de) * | 2002-11-21 | 2004-06-03 | Merck Patent Gmbh | Carbonsäureamide |
| EP1590327A1 (en) * | 2002-12-23 | 2005-11-02 | Millennium Pharmaceuticals, Inc. | Ccr8 inhibitors |
| TW200510311A (en) * | 2002-12-23 | 2005-03-16 | Millennium Pharm Inc | CCr8 inhibitors |
| EP1479678A1 (en) * | 2003-05-19 | 2004-11-24 | Aventis Pharma Deutschland GmbH | Pyrazole-derivatives as factor xa inhibitors |
| US7491827B2 (en) * | 2002-12-23 | 2009-02-17 | Millennium Pharmaceuticals, Inc. | Aryl sulfonamides useful as inhibitors of chemokine receptor activity |
| JP4585448B2 (ja) * | 2002-12-23 | 2010-11-24 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 第Ｘａ因子阻害剤としてのピラゾール−誘導体 |
| DE10322469A1 (de) * | 2003-05-19 | 2004-12-16 | Bayer Healthcare Ag | Heterocyclische Verbindungen |
| US7169795B2 (en) * | 2003-09-30 | 2007-01-30 | Bristol Myers Squibb Company | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
-
2005
- 2005-05-20 EP EP05010929A patent/EP1724269A1/en not_active Withdrawn
-
2006
- 2006-05-06 BR BRPI0610320-0A patent/BRPI0610320A2/pt not_active IP Right Cessation
- 2006-05-06 AT AT06753510T patent/ATE452133T1/de active
- 2006-05-06 MX MX2007014274A patent/MX2007014274A/es active IP Right Grant
- 2006-05-06 JP JP2008511587A patent/JP5027802B2/ja not_active Expired - Fee Related
- 2006-05-06 ES ES06753510T patent/ES2338151T3/es active Active
- 2006-05-06 WO PCT/EP2006/004255 patent/WO2006122661A1/en not_active Ceased
- 2006-05-06 DK DK06753510.4T patent/DK1888567T3/da active
- 2006-05-06 AU AU2006246669A patent/AU2006246669B2/en not_active Ceased
- 2006-05-06 CN CN2006800172463A patent/CN101180296B/zh not_active Expired - Fee Related
- 2006-05-06 CA CA2609288A patent/CA2609288C/en not_active Expired - Fee Related
- 2006-05-06 DE DE602006011156T patent/DE602006011156D1/de active Active
- 2006-05-06 EP EP06753510A patent/EP1888567B1/en not_active Not-in-force
- 2006-05-06 PT PT06753510T patent/PT1888567E/pt unknown
- 2006-05-06 KR KR1020077027048A patent/KR101373533B1/ko not_active Expired - Fee Related
- 2006-05-16 PE PE2006000516A patent/PE20061452A1/es not_active Application Discontinuation
- 2006-05-18 GT GT200600211A patent/GT200600211A/es unknown
- 2006-05-18 TW TW095117566A patent/TWI376377B/zh not_active IP Right Cessation
- 2006-05-18 AR ARP060102004A patent/AR053730A1/es not_active Application Discontinuation
- 2006-05-18 MY MYPI20062281 patent/MY150693A/en unknown
- 2006-05-18 SV SV2006002534A patent/SV2007002534A/es unknown
- 2006-05-18 PA PA20068675301A patent/PA8675301A1/es unknown
- 2006-05-19 DO DO2006000119A patent/DOP2006000119A/es unknown
- 2006-05-19 UY UY29550A patent/UY29550A1/es unknown
-
2007
- 2007-11-15 IL IL187430A patent/IL187430A/en not_active IP Right Cessation
- 2007-11-15 US US11/940,654 patent/US8088925B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GT200700039A (es) | Derivados de triazolopirazina | |
| GT200500208A (es) | Indazoles ùtiles para tratar enfermedades cardiovasculares | |
| CY1119515T1 (el) | Οξαζολο υποκατεστημενα ινδαζολια ως αναστολεις ρι3-κινασης | |
| GT200500103A (es) | 4-fenilamino-quinazolin-6-il-amidas | |
| GT200500101A (es) | Compuestos de metil-aril o heteroaril-amida sustituida | |
| GT200700077A (es) | Compuestos de 4-metilpiridopirimidinona | |
| GT200500286A (es) | Analogos de anilino-pirimidina | |
| GT200800258A (es) | Compuestos de pirrolo-pirimidina y sus usos | |
| CU20090017A7 (es) | Peptidomimeticos de smac utiles como inhibidores de proteinas de apoptosis (iap) | |
| GT200300285A (es) | Nuevos enantiomeros (r) y (s) de derivados del acido tiofeno hidroxamico | |
| GT200600306A (es) | Inhibidores de glutamato agrecanasa | |
| BR122019015876B8 (pt) | compostos derivados de 1,2,5-oxadiazóis, composição, bem como seus usos | |
| SV2011003855A (es) | Heteroarilos sustituidos | |
| CY1112102T1 (el) | Υποκατεστημενες πυριμιδοδιαζεπινες χρησιμες ως αναστολεις plk1 | |
| ECSP11010804A (es) | Compuestos orgánicos | |
| NI201100081A (es) | Aminotetrahidropiranos como inhibidores de dipeptidil peptidasa - iv para el tratamiento o prevención de diabetes. | |
| CR20110013A (es) | Derivados de Heteroarilo como Inhibidores de DGAT1 | |
| MX2010009416A (es) | Compuestos heterociclicos como inhibidores de cxcr2. | |
| GT200400268A (es) | Pirido[2,3-d] pirimidina-2,4-diaminas como inhibidores de pde 2 | |
| MX2011010451A (es) | Derivados de oxadiazol. | |
| CY1113716T1 (el) | Νεα μεθοδος συνθεσης της αγομελατινης | |
| HN2011001606A (es) | Antagonistas de 4-azetidinil -1-heteroaril -ciclohexanol de ccr2 | |
| GT200300033A (es) | Derivados de nicotinamida utiles como inhibidores de pde4 | |
| CY1112829T1 (el) | Νεα μεθοδος συνθεσης για την αγομελατινη | |
| GT200600030A (es) | 2-fenil-indoles como antagonistas del receptor de la prostaglandina d2 |