GT200500123A - Derivados de benceno halogenados del acido aminoisoftalico sustituidos con macrociclos trimeros. - Google Patents

Derivados de benceno halogenados del acido aminoisoftalico sustituidos con macrociclos trimeros.

Info

Publication number
GT200500123A
GT200500123A GT200500123A GT200500123A GT200500123A GT 200500123 A GT200500123 A GT 200500123A GT 200500123 A GT200500123 A GT 200500123A GT 200500123 A GT200500123 A GT 200500123A GT 200500123 A GT200500123 A GT 200500123A
Authority
GT
Guatemala
Prior art keywords
macrocicles
aminoisoftalic
acid replaced
benzen
derivatives halogenated
Prior art date
Application number
GT200500123A
Other languages
English (en)
Inventor
Juan R Harto
Jose L Martin
Johanes Platzek
Heiko Schirmer
Hanns-Joachim Weinmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200500123A publication Critical patent/GT200500123A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPLEJOS METALICOS DE LA FORMULA GENERAL I, DICHOS COMPLEJOS TIENE APLICABILIDAD COMO MEDIOS DE CONTRASTE EN EL DIAGNOSTICO DE POR MEDIO DE RAYOS X Y RESONANCIA MAGNETICA.
GT200500123A 2004-05-25 2005-05-20 Derivados de benceno halogenados del acido aminoisoftalico sustituidos con macrociclos trimeros. GT200500123A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004026103A DE102004026103A1 (de) 2004-05-25 2004-05-25 Trimere makrocyclisch substituierte Aminoisophthalsäure-Halogen-Benzolderivate

Publications (1)

Publication Number Publication Date
GT200500123A true GT200500123A (es) 2006-03-17

Family

ID=34967416

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200500123A GT200500123A (es) 2004-05-25 2005-05-20 Derivados de benceno halogenados del acido aminoisoftalico sustituidos con macrociclos trimeros.

Country Status (12)

Country Link
US (1) US20060120965A1 (es)
EP (1) EP1748992A1 (es)
JP (1) JP2008500293A (es)
AR (1) AR050156A1 (es)
DE (1) DE102004026103A1 (es)
GT (1) GT200500123A (es)
PA (1) PA8634301A1 (es)
PE (1) PE20060365A1 (es)
SV (1) SV2005002124A (es)
TW (1) TW200616982A (es)
UY (1) UY28919A1 (es)
WO (1) WO2005115997A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
RU2755181C2 (ru) 2016-11-28 2021-09-14 Байер Фарма Акциенгезельшафт Новые хелатные соединения гадолиния с высокой релаксивностью для применения в магнитно-резонансной визуализации
MX2021006024A (es) 2018-11-23 2021-07-06 Bayer Ag Formulacion de medios de contraste y proceso para prepararlos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324503A (en) * 1992-02-06 1994-06-28 Mallinckrodt Medical, Inc. Iodo-phenylated chelates for x-ray contrast
JPH08510458A (ja) * 1993-06-02 1996-11-05 ブラッコ エッセ．ピ．ア． 沃素化された常磁性キレートおよびそれらの造影剤としての使用法
US7208140B2 (en) * 2003-02-19 2007-04-24 Schering Aktiengesellschaft Trimeric macrocyclic substituted benzene derivatives
DE10307759B3 (de) * 2003-02-19 2004-11-18 Schering Ag Trimere makrocyclisch substituierte Benzolderivate, deren Herstellung und Verwendung als Kontrastmittel sowie diese enthaltende pharmazeutische Mittel

Also Published As

Publication number Publication date
EP1748992A1 (de) 2007-02-07
JP2008500293A (ja) 2008-01-10
AR050156A1 (es) 2006-10-04
UY28919A1 (es) 2005-12-30
TW200616982A (en) 2006-06-01
PE20060365A1 (es) 2006-05-27
WO2005115997A1 (de) 2005-12-08
US20060120965A1 (en) 2006-06-08
PA8634301A1 (es) 2006-07-03
SV2005002124A (es) 2005-12-06
DE102004026103A1 (de) 2005-12-22

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