GR990300043T1 - Lactoferrin variants and uses thereof - Google Patents

Lactoferrin variants and uses thereof

Info

Publication number
GR990300043T1
GR990300043T1 GR990300043T GR990300043T GR990300043T1 GR 990300043 T1 GR990300043 T1 GR 990300043T1 GR 990300043 T GR990300043 T GR 990300043T GR 990300043 T GR990300043 T GR 990300043T GR 990300043 T1 GR990300043 T1 GR 990300043T1
Authority
GR
Greece
Prior art keywords
lactoferrin variants
lactoferrin
variants
Prior art date
Application number
GR990300043T
Other languages
English (en)
Inventor
Orla M Conneely
Pauline P Ward
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Publication of GR990300043T1 publication Critical patent/GR990300043T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40Transferrins, e.g. lactoferrins, ovotransferrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79Transferrins, e.g. lactoferrins, ovotransferrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
GR990300043T 1996-05-31 1997-06-02 Lactoferrin variants and uses thereof GR990300043T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1874796P 1996-05-31 1996-05-31
US08/866,544 US6111081A (en) 1996-05-31 1997-05-30 Lactoferrin variants and uses thereof
PCT/US1997/009531 WO1997045136A1 (en) 1996-05-31 1997-06-02 Lactoferrin variants and uses thereof

Publications (1)

Publication Number Publication Date
GR990300043T1 true GR990300043T1 (en) 2000-01-31

Family

ID=26691448

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990300043T GR990300043T1 (en) 1996-05-31 1997-06-02 Lactoferrin variants and uses thereof

Country Status (12)

Country Link
US (1) US6111081A (el)
EP (1) EP0959898A4 (el)
JP (1) JP2000511424A (el)
KR (1) KR20000016159A (el)
AU (1) AU707476B2 (el)
CA (1) CA2256453A1 (el)
DE (1) DE959898T1 (el)
ES (1) ES2140362T1 (el)
GR (1) GR990300043T1 (el)
IL (1) IL127319A (el)
NZ (1) NZ333215A (el)
WO (1) WO1997045136A1 (el)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94183A (en) * 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
JP2002515893A (ja) * 1997-02-03 2002-05-28 ファーミング インテレクチュアル プロパティ ビーブイ ヒトラクトフェリンおよびその改変体の有用な特性
EP0979099B1 (en) * 1997-04-10 2005-06-15 Agennix, Inc. Use of lactoferin in the treatment of allergen induced disorders
US6399570B1 (en) * 1999-02-05 2002-06-04 Agennix, Inc. Antimicrobial/endotoxin neutralizing polypeptide
AU2002359949A1 (en) * 2001-12-28 2003-07-24 Nrl Pharma, Inc. Compositions for improving lipid metabolism
US20030213007A1 (en) * 2002-03-27 2003-11-13 Slattery Charles Wilbur Human milk produced by human mammary tissue implanted in non-human host animals and uses thereof
US20040082504A1 (en) 2002-05-10 2004-04-29 Atul Varadhachary Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases
AU2003233583A1 (en) * 2002-05-24 2003-12-12 Agennix Incorporated Oral lactoferrin in the treatment of respiratory disorders
ES2358645T3 (es) * 2002-09-16 2011-05-12 Agennix Incorporated Composiciones de lactoferrina y métodos de tratamiento de la úlcera diabética.
EP1581243A4 (en) * 2002-12-06 2008-01-02 Agennix Inc ORAL LACTOFERRINE FOR THE TREATMENT OF SEPSIES
US7592306B2 (en) * 2002-12-10 2009-09-22 Agennix, Inc. Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
AU2002360677A1 (en) * 2002-12-20 2004-07-29 Ventria Bioscience Lactoferrin protein with iron for treating iron deficiency and anemia
US8105615B2 (en) * 2003-06-06 2012-01-31 Agennix Incorporated Lactoferrin as an adjuvant in cancer vaccines
US20040259770A1 (en) * 2003-06-19 2004-12-23 Rush University Medical Center Method for determining leukocyte activation
WO2005018542A2 (en) * 2003-07-10 2005-03-03 Agennix Incorporated Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects
US7183381B2 (en) * 2004-10-26 2007-02-27 Agennix, Inc. Composition of lactoferrin related peptides and uses thereof
NZ555163A (en) 2007-05-14 2010-05-28 Fonterra Co Operative Group Methods of immune or hematological enhancement, inhibiting tumour formation or growth, and treating or preventing cancer, cancer symptoms, or the symptoms of cancer treatments
BR112014026162A2 (pt) * 2012-04-23 2017-10-03 Nrl Pharma Inc Proteína de fusão ou variante da mesma, molécula de ácido nucleico, vetor de expressão, célula hospedeira, animal não humano geneticamente modificado, planta geneticamente modificada, agente terapêutico para doenças melhoradas por lactoferrina, composição farmacêutica, e, método para preparar a proteína de fusão ou variante da mesma
EP3533870A4 (en) 2016-10-28 2020-04-08 NRL Pharma, Inc. LACTOFERRIN / ALBUMIN FUSION PROTEIN AND PRODUCTION METHOD THEREFOR

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
GB1575343A (en) * 1977-05-10 1980-09-17 Ici Ltd Method for preparing liposome compositions containing biologically active compounds
US4529561A (en) * 1978-03-24 1985-07-16 The Regents Of The University Of California Method for producing liposomes in selected size range
IN150740B (el) * 1978-11-24 1982-12-04 Hoffmann La Roche
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
US4634665A (en) * 1980-02-25 1987-01-06 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4394443A (en) * 1980-12-18 1983-07-19 Yale University Method for cloning genes
US4452747A (en) * 1982-03-22 1984-06-05 Klaus Gersonde Method of and arrangement for producing lipid vesicles
US4766075A (en) * 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
US4725442A (en) * 1983-06-17 1988-02-16 Haynes Duncan H Microdroplets of water-insoluble drugs and injectable formulations containing same
US4703008A (en) * 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
US4740461A (en) * 1983-12-27 1988-04-26 Genetics Institute, Inc. Vectors and methods for transformation of eucaryotic cells
US4710465A (en) * 1984-04-19 1987-12-01 Yale University Junction-fragment DNA probes and probe clusters
US5008050A (en) * 1984-06-20 1991-04-16 The Liposome Company, Inc. Extrusion technique for producing unilamellar vesicles
LU85479A1 (fr) * 1984-07-25 1986-02-12 Oleofina Sa Compositions antibacteriennes de nourriture pour animaux et procede pour les preparer
US4921706A (en) * 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
JPS61145200A (ja) * 1984-12-19 1986-07-02 Snow Brand Milk Prod Co Ltd ウシラクトフェリンの分離精製法
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
EP0206783A3 (en) * 1985-06-20 1988-10-05 The Salk Institute Biotechnology Industrial Associates, Inc. Expression and secretion of polypeptides from saccharomyces cerevisiae
FR2583676B1 (fr) * 1985-06-24 1988-03-25 Induplast Sa Procede et appareils d'extrusion de structures alveolaires en matiere thermoplastique et structures ainsi obtenues
US4959318A (en) * 1985-06-27 1990-09-25 Zymogenetics, Inc. Expression of protein C
US4800159A (en) * 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4737323A (en) * 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US4965190A (en) * 1986-07-31 1990-10-23 Howard Hughes Medical Institute Methods for the identification of mutations in the human phenylalanine hydroxylase gene using DNA probes
US4920016A (en) * 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
US5009956A (en) * 1987-02-24 1991-04-23 Univ Minnesota Phospholipase A2-resistant liposomes
US5019508A (en) * 1987-08-27 1991-05-28 Biotechnology Research Partners, Ltd. Synovial phospholipases
EP0383779B2 (en) * 1987-09-04 2000-05-31 Novo Nordisk A/S PROCESS FOR THE PRODUCTION OF PROTEIN PRODUCTS IN $i(ASPERGILLUS) AND PROMOTERS FOR USE IN $i(ASPERGILLUS)
US5081227A (en) * 1988-03-04 1992-01-14 La Jolla Cancer Research Foundation Germ cell alkaline phosphatase
US4927637A (en) * 1989-01-17 1990-05-22 Liposome Technology, Inc. Liposome extrusion method
US4944948A (en) * 1989-02-24 1990-07-31 Liposome Technology, Inc. EGF/Liposome gel composition and method
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
US5571697A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Texas Medical Center Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus
US5155037A (en) * 1989-08-04 1992-10-13 The Texas A&M University System Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems
WO1991005045A1 (en) * 1989-09-28 1991-04-18 Granada Biosciences, Inc. PORCINE LACTOFERRIN AMINO ACID AND cDNA SEQUENCE
WO1991013982A1 (en) * 1990-03-08 1991-09-19 Ferrodynamics, Inc. Genetically engineered human lactoferrin
JP2818056B2 (ja) * 1990-09-07 1998-10-30 森永乳業株式会社 抗菌性ペプチドおよび抗菌剤
US5166145A (en) * 1990-09-10 1992-11-24 Alza Corporation Antiemetic therapy
NZ245713A (en) * 1992-02-10 1994-12-22 Novopharm Ltd Production of the antibiotic lovastatin from genetically engineered aspergillus strains
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
US5571619A (en) * 1994-05-24 1996-11-05 Exxon Chemical Patents, Inc. Fibers and oriented films of polypropylene higher α-olefin copolymers

Also Published As

Publication number Publication date
DE959898T1 (de) 2000-05-04
CA2256453A1 (en) 1997-12-04
AU3227197A (en) 1998-01-05
EP0959898A1 (en) 1999-12-01
KR20000016159A (ko) 2000-03-25
WO1997045136A1 (en) 1997-12-04
ES2140362T1 (es) 2000-03-01
US6111081A (en) 2000-08-29
EP0959898A4 (en) 2002-08-14
NZ333215A (en) 2000-05-26
IL127319A (en) 2004-08-31
AU707476B2 (en) 1999-07-08
JP2000511424A (ja) 2000-09-05
IL127319A0 (en) 1999-09-22

Similar Documents

Publication Publication Date Title
EP1021185A4 (en) DIHYDROPYRIMIDINE AND ITS USES.
GB2333453B (en) Colostrinin and uses thereof
EP0894807A4 (en) GPIb lipid complex and its applications
GB9620390D0 (en) Substances and their uses
ZA9711141B (en) Novel ketobenzamides and their use
IL122428A0 (en) Minizymes and minribozymes and uses thereof
GR990300043T1 (en) Lactoferrin variants and uses thereof
GB9625899D0 (en) Substances and their uses
HUP9700446A3 (en) Oilsuspension-concentrate and using thereof
GB9608130D0 (en) Adam proteins and uses thereof
ZA96428B (en) P-heteroatom-substituted phenols and uses thereof
GB9719046D0 (en) Device and assembly
GB9609339D0 (en) Device and assembly
PL331523A1 (en) Azolotrizines and azolopyrimidines
IL121361A0 (en) Aprotinin variants and their use
IL125548A0 (en) Cardiotrophin and uses therefor
GB9423372D0 (en) Proteins and their uses
GB2315463B (en) Tags and components thereof
PL328334A1 (en) Preparation and application thereof
EP0998578A4 (en) SEL-10 AND USES OF SEL-10
HUP9900068A3 (en) Fuse-switch and/or fuse-disconnector
PL341293A1 (en) Beta-lypothropin and application thereof
GB9624905D0 (en) MNGEF and homologues thereof
GB2352176B (en) Colostrinin and uses thereof
ZA959512B (en) Aryloxycycloalkenyl and aryloxyiminocycloalkenylhy-droxyureas