GR990300043T1 - Lactoferrin variants and uses thereof - Google Patents
Lactoferrin variants and uses thereofInfo
- Publication number
- GR990300043T1 GR990300043T1 GR990300043T GR990300043T GR990300043T1 GR 990300043 T1 GR990300043 T1 GR 990300043T1 GR 990300043 T GR990300043 T GR 990300043T GR 990300043 T GR990300043 T GR 990300043T GR 990300043 T1 GR990300043 T1 GR 990300043T1
- Authority
- GR
- Greece
- Prior art keywords
- lactoferrin variants
- lactoferrin
- variants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1874796P | 1996-05-31 | 1996-05-31 | |
US08/866,544 US6111081A (en) | 1996-05-31 | 1997-05-30 | Lactoferrin variants and uses thereof |
PCT/US1997/009531 WO1997045136A1 (en) | 1996-05-31 | 1997-06-02 | Lactoferrin variants and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GR990300043T1 true GR990300043T1 (en) | 2000-01-31 |
Family
ID=26691448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR990300043T GR990300043T1 (en) | 1996-05-31 | 1997-06-02 | Lactoferrin variants and uses thereof |
Country Status (12)
Country | Link |
---|---|
US (1) | US6111081A (el) |
EP (1) | EP0959898A4 (el) |
JP (1) | JP2000511424A (el) |
KR (1) | KR20000016159A (el) |
AU (1) | AU707476B2 (el) |
CA (1) | CA2256453A1 (el) |
DE (1) | DE959898T1 (el) |
ES (1) | ES2140362T1 (el) |
GR (1) | GR990300043T1 (el) |
IL (1) | IL127319A (el) |
NZ (1) | NZ333215A (el) |
WO (1) | WO1997045136A1 (el) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL94183A (en) * | 1989-05-05 | 2003-09-17 | Baylor College Medicine | cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE |
JP2002515893A (ja) * | 1997-02-03 | 2002-05-28 | ファーミング インテレクチュアル プロパティ ビーブイ | ヒトラクトフェリンおよびその改変体の有用な特性 |
EP0979099B1 (en) * | 1997-04-10 | 2005-06-15 | Agennix, Inc. | Use of lactoferin in the treatment of allergen induced disorders |
US6399570B1 (en) * | 1999-02-05 | 2002-06-04 | Agennix, Inc. | Antimicrobial/endotoxin neutralizing polypeptide |
AU2002359949A1 (en) * | 2001-12-28 | 2003-07-24 | Nrl Pharma, Inc. | Compositions for improving lipid metabolism |
US20030213007A1 (en) * | 2002-03-27 | 2003-11-13 | Slattery Charles Wilbur | Human milk produced by human mammary tissue implanted in non-human host animals and uses thereof |
US20040082504A1 (en) | 2002-05-10 | 2004-04-29 | Atul Varadhachary | Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases |
AU2003233583A1 (en) * | 2002-05-24 | 2003-12-12 | Agennix Incorporated | Oral lactoferrin in the treatment of respiratory disorders |
ES2358645T3 (es) * | 2002-09-16 | 2011-05-12 | Agennix Incorporated | Composiciones de lactoferrina y métodos de tratamiento de la úlcera diabética. |
EP1581243A4 (en) * | 2002-12-06 | 2008-01-02 | Agennix Inc | ORAL LACTOFERRINE FOR THE TREATMENT OF SEPSIES |
US7592306B2 (en) * | 2002-12-10 | 2009-09-22 | Agennix, Inc. | Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease |
AU2002360677A1 (en) * | 2002-12-20 | 2004-07-29 | Ventria Bioscience | Lactoferrin protein with iron for treating iron deficiency and anemia |
US8105615B2 (en) * | 2003-06-06 | 2012-01-31 | Agennix Incorporated | Lactoferrin as an adjuvant in cancer vaccines |
US20040259770A1 (en) * | 2003-06-19 | 2004-12-23 | Rush University Medical Center | Method for determining leukocyte activation |
WO2005018542A2 (en) * | 2003-07-10 | 2005-03-03 | Agennix Incorporated | Use of lactoferrin in prophylaxis against infection and/or inflammation in immunosuppressed subjects |
US7183381B2 (en) * | 2004-10-26 | 2007-02-27 | Agennix, Inc. | Composition of lactoferrin related peptides and uses thereof |
NZ555163A (en) | 2007-05-14 | 2010-05-28 | Fonterra Co Operative Group | Methods of immune or hematological enhancement, inhibiting tumour formation or growth, and treating or preventing cancer, cancer symptoms, or the symptoms of cancer treatments |
BR112014026162A2 (pt) * | 2012-04-23 | 2017-10-03 | Nrl Pharma Inc | Proteína de fusão ou variante da mesma, molécula de ácido nucleico, vetor de expressão, célula hospedeira, animal não humano geneticamente modificado, planta geneticamente modificada, agente terapêutico para doenças melhoradas por lactoferrina, composição farmacêutica, e, método para preparar a proteína de fusão ou variante da mesma |
EP3533870A4 (en) | 2016-10-28 | 2020-04-08 | NRL Pharma, Inc. | LACTOFERRIN / ALBUMIN FUSION PROTEIN AND PRODUCTION METHOD THEREFOR |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5186117A (en) * | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
US4529561A (en) * | 1978-03-24 | 1985-07-16 | The Regents Of The University Of California | Method for producing liposomes in selected size range |
IN150740B (el) * | 1978-11-24 | 1982-12-04 | Hoffmann La Roche | |
GB2046092B (en) * | 1979-03-05 | 1983-11-02 | Toyama Chemical Co Ltd | Pharmaceutical composition containing a lysophospholid and a phospholipid |
US4634665A (en) * | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4394443A (en) * | 1980-12-18 | 1983-07-19 | Yale University | Method for cloning genes |
US4452747A (en) * | 1982-03-22 | 1984-06-05 | Klaus Gersonde | Method of and arrangement for producing lipid vesicles |
US4766075A (en) * | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
US4652639A (en) * | 1982-05-06 | 1987-03-24 | Amgen | Manufacture and expression of structural genes |
US4725442A (en) * | 1983-06-17 | 1988-02-16 | Haynes Duncan H | Microdroplets of water-insoluble drugs and injectable formulations containing same |
US4703008A (en) * | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
US4740461A (en) * | 1983-12-27 | 1988-04-26 | Genetics Institute, Inc. | Vectors and methods for transformation of eucaryotic cells |
US4710465A (en) * | 1984-04-19 | 1987-12-01 | Yale University | Junction-fragment DNA probes and probe clusters |
US5008050A (en) * | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
LU85479A1 (fr) * | 1984-07-25 | 1986-02-12 | Oleofina Sa | Compositions antibacteriennes de nourriture pour animaux et procede pour les preparer |
US4921706A (en) * | 1984-11-20 | 1990-05-01 | Massachusetts Institute Of Technology | Unilamellar lipid vesicles and method for their formation |
JPS61145200A (ja) * | 1984-12-19 | 1986-07-02 | Snow Brand Milk Prod Co Ltd | ウシラクトフェリンの分離精製法 |
US4886747A (en) * | 1985-03-22 | 1989-12-12 | Genentech, Inc. | Nucleic acid encoding TGF-β and its uses |
EP0206783A3 (en) * | 1985-06-20 | 1988-10-05 | The Salk Institute Biotechnology Industrial Associates, Inc. | Expression and secretion of polypeptides from saccharomyces cerevisiae |
FR2583676B1 (fr) * | 1985-06-24 | 1988-03-25 | Induplast Sa | Procede et appareils d'extrusion de structures alveolaires en matiere thermoplastique et structures ainsi obtenues |
US4959318A (en) * | 1985-06-27 | 1990-09-25 | Zymogenetics, Inc. | Expression of protein C |
US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US4737323A (en) * | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
US4965190A (en) * | 1986-07-31 | 1990-10-23 | Howard Hughes Medical Institute | Methods for the identification of mutations in the human phenylalanine hydroxylase gene using DNA probes |
US4920016A (en) * | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
US5009956A (en) * | 1987-02-24 | 1991-04-23 | Univ Minnesota | Phospholipase A2-resistant liposomes |
US5019508A (en) * | 1987-08-27 | 1991-05-28 | Biotechnology Research Partners, Ltd. | Synovial phospholipases |
EP0383779B2 (en) * | 1987-09-04 | 2000-05-31 | Novo Nordisk A/S | PROCESS FOR THE PRODUCTION OF PROTEIN PRODUCTS IN $i(ASPERGILLUS) AND PROMOTERS FOR USE IN $i(ASPERGILLUS) |
US5081227A (en) * | 1988-03-04 | 1992-01-14 | La Jolla Cancer Research Foundation | Germ cell alkaline phosphatase |
US4927637A (en) * | 1989-01-17 | 1990-05-22 | Liposome Technology, Inc. | Liposome extrusion method |
US4944948A (en) * | 1989-02-24 | 1990-07-31 | Liposome Technology, Inc. | EGF/Liposome gel composition and method |
US5571691A (en) * | 1989-05-05 | 1996-11-05 | Baylor College Of Medicine | Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms |
US5571697A (en) * | 1989-05-05 | 1996-11-05 | Baylor College Of Medicine Texas Medical Center | Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus |
US5155037A (en) * | 1989-08-04 | 1992-10-13 | The Texas A&M University System | Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems |
WO1991005045A1 (en) * | 1989-09-28 | 1991-04-18 | Granada Biosciences, Inc. | PORCINE LACTOFERRIN AMINO ACID AND cDNA SEQUENCE |
WO1991013982A1 (en) * | 1990-03-08 | 1991-09-19 | Ferrodynamics, Inc. | Genetically engineered human lactoferrin |
JP2818056B2 (ja) * | 1990-09-07 | 1998-10-30 | 森永乳業株式会社 | 抗菌性ペプチドおよび抗菌剤 |
US5166145A (en) * | 1990-09-10 | 1992-11-24 | Alza Corporation | Antiemetic therapy |
NZ245713A (en) * | 1992-02-10 | 1994-12-22 | Novopharm Ltd | Production of the antibiotic lovastatin from genetically engineered aspergillus strains |
ZA932568B (en) * | 1992-04-24 | 1993-11-12 | Baylor College Midecine A Non | Production of recombinant human lactoferrin |
US5571619A (en) * | 1994-05-24 | 1996-11-05 | Exxon Chemical Patents, Inc. | Fibers and oriented films of polypropylene higher α-olefin copolymers |
-
1997
- 1997-05-30 US US08/866,544 patent/US6111081A/en not_active Expired - Lifetime
- 1997-06-02 NZ NZ333215A patent/NZ333215A/xx not_active IP Right Cessation
- 1997-06-02 AU AU32271/97A patent/AU707476B2/en not_active Ceased
- 1997-06-02 KR KR1019980709727A patent/KR20000016159A/ko not_active Application Discontinuation
- 1997-06-02 JP JP09543045A patent/JP2000511424A/ja not_active Ceased
- 1997-06-02 WO PCT/US1997/009531 patent/WO1997045136A1/en not_active Application Discontinuation
- 1997-06-02 IL IL12731997A patent/IL127319A/en not_active IP Right Cessation
- 1997-06-02 EP EP97927932A patent/EP0959898A4/en not_active Withdrawn
- 1997-06-02 ES ES97927932T patent/ES2140362T1/es active Pending
- 1997-06-02 DE DE0959898T patent/DE959898T1/de active Pending
- 1997-06-02 CA CA002256453A patent/CA2256453A1/en not_active Abandoned
- 1997-06-02 GR GR990300043T patent/GR990300043T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE959898T1 (de) | 2000-05-04 |
CA2256453A1 (en) | 1997-12-04 |
AU3227197A (en) | 1998-01-05 |
EP0959898A1 (en) | 1999-12-01 |
KR20000016159A (ko) | 2000-03-25 |
WO1997045136A1 (en) | 1997-12-04 |
ES2140362T1 (es) | 2000-03-01 |
US6111081A (en) | 2000-08-29 |
EP0959898A4 (en) | 2002-08-14 |
NZ333215A (en) | 2000-05-26 |
IL127319A (en) | 2004-08-31 |
AU707476B2 (en) | 1999-07-08 |
JP2000511424A (ja) | 2000-09-05 |
IL127319A0 (en) | 1999-09-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1021185A4 (en) | DIHYDROPYRIMIDINE AND ITS USES. | |
GB2333453B (en) | Colostrinin and uses thereof | |
EP0894807A4 (en) | GPIb lipid complex and its applications | |
GB9620390D0 (en) | Substances and their uses | |
ZA9711141B (en) | Novel ketobenzamides and their use | |
IL122428A0 (en) | Minizymes and minribozymes and uses thereof | |
GR990300043T1 (en) | Lactoferrin variants and uses thereof | |
GB9625899D0 (en) | Substances and their uses | |
HUP9700446A3 (en) | Oilsuspension-concentrate and using thereof | |
GB9608130D0 (en) | Adam proteins and uses thereof | |
ZA96428B (en) | P-heteroatom-substituted phenols and uses thereof | |
GB9719046D0 (en) | Device and assembly | |
GB9609339D0 (en) | Device and assembly | |
PL331523A1 (en) | Azolotrizines and azolopyrimidines | |
IL121361A0 (en) | Aprotinin variants and their use | |
IL125548A0 (en) | Cardiotrophin and uses therefor | |
GB9423372D0 (en) | Proteins and their uses | |
GB2315463B (en) | Tags and components thereof | |
PL328334A1 (en) | Preparation and application thereof | |
EP0998578A4 (en) | SEL-10 AND USES OF SEL-10 | |
HUP9900068A3 (en) | Fuse-switch and/or fuse-disconnector | |
PL341293A1 (en) | Beta-lypothropin and application thereof | |
GB9624905D0 (en) | MNGEF and homologues thereof | |
GB2352176B (en) | Colostrinin and uses thereof | |
ZA959512B (en) | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhy-droxyureas |