GR970300046T1 - Nucleic acid encoding neuropeptide y/peptide yy (y2) receptors and uses thereof - Google Patents
Nucleic acid encoding neuropeptide y/peptide yy (y2) receptors and uses thereofInfo
- Publication number
- GR970300046T1 GR970300046T1 GR970300046T GR970300046T GR970300046T1 GR 970300046 T1 GR970300046 T1 GR 970300046T1 GR 970300046 T GR970300046 T GR 970300046T GR 970300046 T GR970300046 T GR 970300046T GR 970300046 T1 GR970300046 T1 GR 970300046T1
- Authority
- GR
- Greece
- Prior art keywords
- receptors
- peptide
- nucleic acid
- acid encoding
- encoding neuropeptide
- Prior art date
Links
- 101710151321 Melanostatin Proteins 0.000 title 1
- 102400000064 Neuropeptide Y Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/192,288 US5545549A (en) | 1994-02-03 | 1994-02-03 | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
| PCT/US1995/001469 WO1995021245A1 (en) | 1994-02-03 | 1995-02-03 | Nucleic acid encoding neuropeptide y/peptide yy (y2) receptors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR970300046T1 true GR970300046T1 (en) | 1997-12-31 |
Family
ID=22709058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR970300046T GR970300046T1 (en) | 1994-02-03 | 1997-12-31 | Nucleic acid encoding neuropeptide y/peptide yy (y2) receptors and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US5545549A (el) |
| EP (1) | EP0802972A4 (el) |
| JP (1) | JPH09509314A (el) |
| AU (1) | AU697271B2 (el) |
| CA (1) | CA2159217A1 (el) |
| DE (1) | DE802972T1 (el) |
| ES (1) | ES2107398T1 (el) |
| GR (1) | GR970300046T1 (el) |
| WO (1) | WO1995021245A1 (el) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545549A (en) * | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
| JPH10508486A (ja) * | 1994-11-07 | 1998-08-25 | メルク エンド カンパニー インコーポレーテッド | 修飾神経ペプチドｙレセプター |
| US5602024A (en) * | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
| US5989920A (en) | 1994-12-02 | 1999-11-23 | Synaptic Pharmaceutical Corporation | Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5 |
| US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| DE69739366D1 (de) | 1996-03-01 | 2009-05-28 | Euroscreen Sa | Aktive und inactive CC-Chemokinrezeptoren und Nukleinsäuremoleküle, die für diesen Rezeptor kodieren |
| US5919901A (en) * | 1996-04-08 | 1999-07-06 | Bayer Corporation | Neuropeptide Y receptor Y5 and nucleic acid sequences |
| US5965392A (en) * | 1996-04-08 | 1999-10-12 | Bayer Corporation | Neuropeptide Y receptor Y5 and nucleic acid sequences |
| US6355478B1 (en) * | 1996-06-17 | 2002-03-12 | Eli Lilly And Company | Rhesus monkey neuropeptide Y Y2 receptor |
| US5908830A (en) * | 1996-10-31 | 1999-06-01 | Merck & Co., Inc. | Combination therapy for the treatment of diabetes and obesity |
| US5817912A (en) * | 1997-01-16 | 1998-10-06 | B.M.R.A. Corporation B.V. | Transgenic mice with disrupted NPY Y1 receptor genes |
| US6713265B1 (en) | 1997-06-04 | 2004-03-30 | Synaptic Pharmaceutical Corporation | Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) |
| US5916869A (en) * | 1997-06-13 | 1999-06-29 | North Carolina State University | Method of treating birds in ovo |
| US6031090A (en) * | 1998-08-07 | 2000-02-29 | Smithkline Beecham Corporation | Molecular cloning of a 7TM receptor (GPR31A) |
| US7070955B2 (en) * | 1998-08-10 | 2006-07-04 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| ATE314371T1 (de) | 1998-11-10 | 2006-01-15 | Merck & Co Inc | Spiro-indole als y5-rezeptor antagonisten |
| US7745216B2 (en) * | 1999-02-10 | 2010-06-29 | Curis, Inc. | Methods and reagents for treating glucose metabolic disorders |
| US6221660B1 (en) | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
| CA2387711A1 (en) * | 1999-08-27 | 2001-03-08 | Takeda Chemical Industries, Ltd. | Novel g protein-coupled receptor protein and dna thereof |
| AU2001232900A1 (en) * | 2000-01-20 | 2001-07-31 | Michael Amling | Methods and compositions for control of bone formation via modulation of neuropeptide y activity |
| CN1568195B (zh) * | 2000-12-14 | 2011-03-02 | 安米林药品公司 | 用于治疗代谢性疾病的肽yy及肽yy激动剂 |
| DE10116829A1 (de) * | 2001-04-04 | 2002-11-14 | Nascacell Gmbh | Neuropeptid bindende Nukleinsäuren |
| GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| WO2003026591A2 (en) | 2001-09-24 | 2003-04-03 | Imperial College Innovations Ltd. | Modification of feeding behavior |
| US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
| SE0200531D0 (sv) * | 2002-02-22 | 2002-02-22 | Avaris Ab | Novel biomolecular complexes, method for their production and use |
| WO2003088904A2 (en) * | 2002-04-15 | 2003-10-30 | The Regents Of The University Of California | Screening and therapeutic methods for treating circadian rhythm disorders |
| ATE494002T1 (de) * | 2002-06-14 | 2011-01-15 | Amylin Pharmaceuticals Inc | Prävention und/oder behandlung von colitis ulcerosa mit pyy oder pyyä3-36ü |
| US20040006004A1 (en) * | 2002-06-27 | 2004-01-08 | Markku Koulu | Method for prevention and treatment of diseases or disorders related to excessive formation of vascular tissue or blood vessels |
| US20040254131A1 (en) * | 2003-06-16 | 2004-12-16 | Markku Koulu | Method for prevention or treatment of diseases or disorders related to excessive formation of vascular tissue or blood vessels |
| GB0300571D0 (en) * | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
| EP1583549A4 (en) * | 2003-01-17 | 2006-10-04 | Sod Conseils Rech Applic | YY PEPTIDE ANALOGS |
| EP1789440A4 (en) | 2004-02-11 | 2008-03-12 | Amylin Pharmaceuticals Inc | REASONS FOR THE FAMILY OF PANCREATIC POLYPEPTIDES AND POLYPEPTIDES CONTAINING THEM |
| US20070270339A1 (en) * | 2004-04-23 | 2007-11-22 | Serono, Inc. | Use of GPCR54 Ligands for the Treatment of Infertility |
| US20080014172A1 (en) * | 2004-05-28 | 2008-01-17 | Applied Research Systems Ars Holding N.V. | Use of Il-17 in the Treatment of Fertility-Related Disorders |
| WO2006036770A2 (en) * | 2004-09-24 | 2006-04-06 | Merck & Co., Inc. | Combination therapy for the treatment of obesity |
| US20090317376A1 (en) * | 2005-06-06 | 2009-12-24 | Georgetown University Medical School | Compositions And Methods For Lipo Modeling |
| CA2611446A1 (en) * | 2005-06-09 | 2006-12-14 | Banyu Pharmaceutical Co., Ltd. | Npy y2 agonist for use as therapeutic agent for disease accompanied by diarrhea |
| GB0511986D0 (en) * | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| TWI428346B (zh) * | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5026685A (en) * | 1988-07-15 | 1991-06-25 | The Salk Institute For Biological Studies | NPY peptide analogs |
| US5328899A (en) * | 1988-07-15 | 1994-07-12 | The Salk Institute For Biological Studies | NPY peptide analogs |
| ZA896376B (en) * | 1988-08-26 | 1990-05-30 | Merrell Dow Pharma | Neuropeptide y agonists |
| ZA896374B (en) * | 1988-08-26 | 1990-05-30 | Merrell Dow Pharma | Neuropeptide y antagonists |
| ZA911364B (en) | 1990-03-29 | 1992-10-28 | Gregory Lyons Beaumont | Anti-bird netting |
| EP0448765B1 (de) * | 1990-03-30 | 1994-08-17 | HEUMANN PHARMA GMBH & CO | Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels mit NPY-antagonistischer Wirkung |
| SE9002278L (sv) * | 1990-06-28 | 1991-12-29 | Perstorp Ab | Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel |
| EP0668910B1 (en) * | 1991-11-06 | 1999-05-26 | Garvan Institute Of Medical Research | Human neuropeptide y-y1 receptor |
| GB9213215D0 (en) * | 1992-06-20 | 1992-08-05 | Wellcome Found | Peptides |
| JPH06116284A (ja) * | 1992-10-02 | 1994-04-26 | Yamanouchi Pharmaceut Co Ltd | 新規ペプチド |
| ES2118372T3 (es) * | 1992-11-17 | 1998-09-16 | Icos Corp | Nuevos receptores siete transmembrana v28. |
| FR2701480B1 (fr) * | 1993-02-15 | 1995-05-24 | Sanofi Elf | Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant. |
| NZ265452A (en) * | 1993-03-29 | 1997-09-22 | Univ Cincinnati | Analogues of peptide yy, dimers and pharmaceutical compositions |
| AU7174494A (en) * | 1993-06-18 | 1995-01-17 | University Of Cincinnati, The | Neuropeptide y antagonists and agonists |
| US5516653A (en) * | 1993-12-28 | 1996-05-14 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof |
| US5545549A (en) * | 1994-02-03 | 1996-08-13 | Synaptic Pharmaceutical Corporation | DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof |
| CA2134428A1 (en) * | 1994-10-26 | 1996-04-27 | Albert Tseng | Neuropeptide y y2 agonist peptides |
| JPH10508486A (ja) * | 1994-11-07 | 1998-08-25 | メルク エンド カンパニー インコーポレーテッド | 修飾神経ペプチドｙレセプター |
| US5602024A (en) * | 1994-12-02 | 1997-02-11 | Synaptic Pharmaceutical Corporation | DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof |
| US5621079A (en) * | 1995-02-03 | 1997-04-15 | Merck & Co., Inc. | Neuropeptide Y receptor |
| AUPN646795A0 (en) * | 1995-11-09 | 1995-11-30 | Garvan Institute Of Medical Research | Neuropeptide Y-Y5 receptor |
| US5965392A (en) * | 1996-04-08 | 1999-10-12 | Bayer Corporation | Neuropeptide Y receptor Y5 and nucleic acid sequences |
| US6355478B1 (en) * | 1996-06-17 | 2002-03-12 | Eli Lilly And Company | Rhesus monkey neuropeptide Y Y2 receptor |
-
1994
- 1994-02-03 US US08/192,288 patent/US5545549A/en not_active Expired - Lifetime
-
1995
- 1995-02-03 JP JP7520786A patent/JPH09509314A/ja active Pending
- 1995-02-03 EP EP95909481A patent/EP0802972A4/en not_active Ceased
- 1995-02-03 DE DE0802972T patent/DE802972T1/de active Pending
- 1995-02-03 AU AU17432/95A patent/AU697271B2/en not_active Ceased
- 1995-02-03 WO PCT/US1995/001469 patent/WO1995021245A1/en not_active Application Discontinuation
- 1995-02-03 ES ES95909481T patent/ES2107398T1/es active Pending
- 1995-02-03 CA CA002159217A patent/CA2159217A1/en not_active Abandoned
- 1995-02-03 US US08/687,355 patent/US5989834A/en not_active Expired - Fee Related
-
1997
- 1997-12-31 GR GR970300046T patent/GR970300046T1/el unknown
-
1999
- 1999-09-29 US US09/407,367 patent/US6420532B1/en not_active Expired - Fee Related
-
2002
- 2002-07-02 US US10/188,619 patent/US20030162944A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2159217A1 (en) | 1995-08-10 |
| WO1995021245A1 (en) | 1995-08-10 |
| US5989834A (en) | 1999-11-23 |
| US6420532B1 (en) | 2002-07-16 |
| EP0802972A1 (en) | 1997-10-29 |
| US20030162944A1 (en) | 2003-08-28 |
| EP0802972A4 (en) | 1998-04-01 |
| AU697271B2 (en) | 1998-10-01 |
| DE802972T1 (de) | 1998-02-19 |
| US5545549A (en) | 1996-08-13 |
| ES2107398T1 (es) | 1997-12-01 |
| JPH09509314A (ja) | 1997-09-22 |
| AU1743295A (en) | 1995-08-21 |
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