GR900100769A - Ανατολείς ριβοζύμου. - Google Patents
Ανατολείς ριβοζύμου.Info
- Publication number
- GR900100769A GR900100769A GR900100769A GR900100769A GR900100769A GR 900100769 A GR900100769 A GR 900100769A GR 900100769 A GR900100769 A GR 900100769A GR 900100769 A GR900100769 A GR 900100769A GR 900100769 A GR900100769 A GR 900100769A
- Authority
- GR
- Greece
- Prior art keywords
- ribozyme
- based compound
- amino acid
- nucleic acid
- animal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Μέθοδος μειώσεως της "εντός ζώντος σώματος" δράσεως επί ενός ζώου της μολύνσεως από ένα οργανισμό ο οποίος έχει ένα ριβό- ζυμο που παρουσιάζει βιολογική δράση. Η μέθοδος αυτή περιλαμβάνει την παροχή μιας χημικής ενώσεως βασιζόμενης σε πυρηνικό οξύ ή σε αμινοξύ, η οποία αλληλεπιδρά ειδικώς με το ριβόζυμο. Η ένωσις η βασιζόμενη σε πυρηνικό οξύ ή σε αμινοξύ εισάγεται κατόπιν εντός του ζώου, κατά τρόπον ώστε να επιτρέπεται η επαφή της ενώσεως αυτής της βασιζόμενης σε πυρηνικό οξύ ή σε αμινοξύ με το ριβόζυμο, οπότε η βιολογική δράσις του ριβοζύμου θα μειώνεται ή θα εξουδετερώνεται. ω
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42770789A | 1989-10-26 | 1989-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR900100769A true GR900100769A (el) | 1992-03-20 |
Family
ID=23695928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR900100769A GR900100769A (el) | 1989-10-26 | 1990-10-24 | Ανατολείς ριβοζύμου. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0497820B1 (el) |
| JP (1) | JPH04505624A (el) |
| AT (1) | ATE139118T1 (el) |
| AU (1) | AU644115B2 (el) |
| CA (1) | CA2071534A1 (el) |
| DE (1) | DE69027441D1 (el) |
| GR (1) | GR900100769A (el) |
| IE (1) | IE903846A1 (el) |
| WO (1) | WO1991006302A1 (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ241311A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Rna sequence having trans-splicing activity, plant strains |
| NZ241310A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Trans-splicing ribozymes |
| EP0674707A4 (en) * | 1992-12-04 | 1998-01-14 | Apollon Inc | COMPOUNDS AND METHODS FOR THE TREATMENT OF LEUCOMA. |
| US6010904A (en) * | 1995-06-07 | 2000-01-04 | The General Hospital Corporation | Cell ablation using trans-splicing ribozymes |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4654326A (en) * | 1984-07-12 | 1987-03-31 | Yair Devash | Inhibition of plant viruses with oligonucleotides |
-
1990
- 1990-10-16 EP EP90915660A patent/EP0497820B1/en not_active Revoked
- 1990-10-16 AU AU66000/90A patent/AU644115B2/en not_active Ceased
- 1990-10-16 WO PCT/US1990/005945 patent/WO1991006302A1/en not_active Application Discontinuation
- 1990-10-16 AT AT90915660T patent/ATE139118T1/de not_active IP Right Cessation
- 1990-10-16 JP JP2514597A patent/JPH04505624A/ja active Pending
- 1990-10-16 CA CA002071534A patent/CA2071534A1/en not_active Abandoned
- 1990-10-16 DE DE69027441T patent/DE69027441D1/de not_active Expired - Lifetime
- 1990-10-24 GR GR900100769A patent/GR900100769A/el unknown
- 1990-10-25 IE IE384690A patent/IE903846A1/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4654326A (en) * | 1984-07-12 | 1987-03-31 | Yair Devash | Inhibition of plant viruses with oligonucleotides |
Non-Patent Citations (6)
| Title |
|---|
| BIOCHEMISTRY vol. 25, no. 16, 1986, pages 4473 - 4478 BASS, B. L. ET AL. 'Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the tetrahymena ribosomal ribonucleic acid precursor' * |
| EMBO JOURNAL vol. 7, no. 8, 1988, EYNSHAM, OXFORD GB pages 2523 - 2532 MUNROE, S.H. 'Antisense RNA inhibits splicing of pre-mRNA in vitro' * |
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA vol. 85, no. 2, January 1988, WASHINGTON US pages 519 - 523 KUHN, R.J. ET AL. 'Construction of a mutagenesis cartridge for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants' * |
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA vol. 86, no. 6, March 1989, WASHINGTON US pages 1831 - 1835 WU, H.-N. ET AL. 'Human hepatitis delta virus RNA subfragments contain an autocleavage activity' * |
| SCIENCE vol. 231, 1986, LANCASTER, PA US pages 470 - 475 ZAUG, A.J. & CECH, T.R. 'The intervening sequence RNA of tetrahymena is an enzyme' * |
| TRENDS IN BIOTECHNOLOGY vol. 8, no. 7, July 1990, CAMBRIDGE GB pages 174 - 178 COTTEN, M. 'The in vivo application of ribozymes' * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2071534A1 (en) | 1991-04-27 |
| AU6600090A (en) | 1991-05-31 |
| IE903846A1 (en) | 1991-05-08 |
| JPH04505624A (ja) | 1992-10-01 |
| WO1991006302A1 (en) | 1991-05-16 |
| EP0497820A1 (en) | 1992-08-12 |
| AU644115B2 (en) | 1993-12-02 |
| DE69027441D1 (en) | 1996-07-18 |
| ATE139118T1 (de) | 1996-06-15 |
| EP0497820B1 (en) | 1996-06-12 |
| EP0497820A4 (en) | 1993-05-05 |
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