GR80827B - Phenobarbital enzyme inhibitors - Google Patents

Phenobarbital enzyme inhibitors

Info

Publication number
GR80827B
GR80827B GR80827A GR840180827A GR80827B GR 80827 B GR80827 B GR 80827B GR 80827 A GR80827 A GR 80827A GR 840180827 A GR840180827 A GR 840180827A GR 80827 B GR80827 B GR 80827B
Authority
GR
Greece
Prior art keywords
phenobarbital
enzyme inhibitors
inhibitors
enzyme
phenobarbital enzyme
Prior art date
Application number
GR80827A
Other languages
English (en)
Inventor
Flentge Arthur Charles
Herrin Raymond Thomas
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/548,743 external-priority patent/US4543412A/en
Priority claimed from US06/548,742 external-priority patent/US4559173A/en
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of GR80827B publication Critical patent/GR80827B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4071Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4075Esters with hydroxyalkyl compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532Seven-(or more) membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/6512Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
GR80827A 1983-11-04 1984-11-02 Phenobarbital enzyme inhibitors GR80827B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/548,743 US4543412A (en) 1983-11-04 1983-11-04 Phenobarbital enzyme inhibitors
US06/548,742 US4559173A (en) 1983-11-04 1983-11-04 N-substituted dibenz[b,f]azepine salts

Publications (1)

Publication Number Publication Date
GR80827B true GR80827B (en) 1985-03-05

Family

ID=27068936

Family Applications (1)

Application Number Title Priority Date Filing Date
GR80827A GR80827B (en) 1983-11-04 1984-11-02 Phenobarbital enzyme inhibitors

Country Status (10)

Country Link
EP (1) EP0141393B1 (el)
KR (1) KR900001620B1 (el)
AU (1) AU566518B2 (el)
CA (1) CA1224783A (el)
DE (1) DE3473456D1 (el)
DK (1) DK522884A (el)
ES (1) ES8700672A1 (el)
GR (1) GR80827B (el)
IE (1) IE58318B1 (el)
IL (1) IL73293A (el)

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US5414085A (en) * 1992-04-06 1995-05-09 Biosite Diagnostics, Inc. Barbiturate derivatives and protein and polypeptide barbiturate derivative conjugates and labels
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JP2015518854A (ja) 2012-05-23 2015-07-06 セリックスビオ プライヴェート リミテッド 多発性硬化症の治療のための組成物および方法
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US9765020B2 (en) 2012-05-23 2017-09-19 Cellix Bio Private Limited Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis
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US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
US9150557B1 (en) 2014-11-05 2015-10-06 Cellix Bio Private Limited Compositions and methods for the treatment of hyperglycemia
US9173877B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
US9290486B1 (en) 2014-11-05 2016-03-22 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy
US9284287B1 (en) 2014-11-05 2016-03-15 Cellix Bio Private Limited Compositions and methods for the suppression of carbonic anhydrase activity
US10208014B2 (en) 2014-11-05 2019-02-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
US9175008B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Prodrugs of anti-platelet agents
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use

Also Published As

Publication number Publication date
DK522884D0 (da) 1984-11-02
IL73293A0 (en) 1985-01-31
EP0141393A2 (en) 1985-05-15
AU566518B2 (en) 1987-10-22
ES537293A0 (es) 1986-10-16
EP0141393A3 (en) 1985-07-03
CA1224783A (en) 1987-07-28
KR900001620B1 (ko) 1990-03-17
EP0141393B1 (en) 1988-08-17
KR850004111A (ko) 1985-07-01
IL73293A (en) 1988-02-29
ES8700672A1 (es) 1986-10-16
IE58318B1 (en) 1993-09-08
AU3471284A (en) 1985-05-09
IE842828L (en) 1985-05-04
DE3473456D1 (en) 1988-09-22
DK522884A (da) 1985-05-05

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