GR74394B - - Google Patents
Info
- Publication number
- GR74394B GR74394B GR60963A GR800160963A GR74394B GR 74394 B GR74394 B GR 74394B GR 60963 A GR60963 A GR 60963A GR 800160963 A GR800160963 A GR 800160963A GR 74394 B GR74394 B GR 74394B
- Authority
- GR
- Greece
- Prior art keywords
- alkyl
- cycloalkyl
- formula
- image
- pyrimido
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- AMBZNXNKAKZDHN-UHFFFAOYSA-N 3,10,12,14-tetrazatetracyclo[7.7.0.02,6.011,15]hexadeca-1,3,5,7,9,11,13,15-octaene Chemical class C1=C2N=CN=C2N=C2C=CC3=CC=NC3=C21 AMBZNXNKAKZDHN-UHFFFAOYSA-N 0.000 abstract 1
- 206010002660 Anoxia Diseases 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- -1 R2=H Chemical group 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7910653A FR2455039A1 (fr) | 1979-04-26 | 1979-04-26 | Pyrimido et imidazo-pyrido-indole-diones et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR74394B true GR74394B (cg-RX-API-DMAC7.html) | 1984-06-28 |
Family
ID=9224796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR60963A GR74394B (cg-RX-API-DMAC7.html) | 1979-04-26 | 1980-01-15 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4358451A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0018857B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS55145689A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE2253T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU528634B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1129854A (cg-RX-API-DMAC7.html) |
| DE (1) | DE3061648D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK16980A (cg-RX-API-DMAC7.html) |
| ES (1) | ES487713A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2455039A1 (cg-RX-API-DMAC7.html) |
| GR (1) | GR74394B (cg-RX-API-DMAC7.html) |
| IL (1) | IL59128A (cg-RX-API-DMAC7.html) |
| NO (1) | NO794271L (cg-RX-API-DMAC7.html) |
| PT (1) | PT70698A (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA80242B (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3246932A1 (de) * | 1982-12-16 | 1984-06-20 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte 5h-pyrimido(5,4-b)indole |
| JP4202250B2 (ja) | 2001-07-25 | 2008-12-24 | バイオマリン ファーマシューティカル インコーポレイテッド | 血液脳関門輸送を調節するための組成物および方法 |
| US7595311B2 (en) | 2002-05-24 | 2009-09-29 | Exelixis, Inc. | Azepinoindole derivatives as pharmaceutical agents |
| TWI329111B (en) | 2002-05-24 | 2010-08-21 | X Ceptor Therapeutics Inc | Azepinoindole and pyridoindole derivatives as pharmaceutical agents |
| CA2789097C (en) | 2005-04-28 | 2017-02-21 | Proteus Digital Health, Inc. | Pharma-informatics system |
| FR2901795A1 (fr) * | 2006-05-30 | 2007-12-07 | Fourtillan Snc | Derives de pyrimidino[1',6'-1,2]pyrido[3,4-b]indoles et leur utilisation en therapeutique |
| WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| AU2010216512B2 (en) | 2009-02-20 | 2016-06-30 | 2-Bbb Medicines B.V. | Glutathione-based drug delivery system |
| JP2012526144A (ja) | 2009-05-06 | 2012-10-25 | ラボラトリー スキン ケア インコーポレイテッド | 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法 |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1076114A (en) * | 1975-02-10 | 1980-04-22 | Mitsubishi Chemical Industries Limited | 1,5-alkylene-3-aryl hydantoin derivatives |
-
1979
- 1979-04-26 FR FR7910653A patent/FR2455039A1/fr active Granted
- 1979-12-27 NO NO794271A patent/NO794271L/no unknown
-
1980
- 1980-01-14 JP JP300380A patent/JPS55145689A/ja active Pending
- 1980-01-15 ZA ZA00800242A patent/ZA80242B/xx unknown
- 1980-01-15 US US06/112,238 patent/US4358451A/en not_active Expired - Lifetime
- 1980-01-15 CA CA343,698A patent/CA1129854A/en not_active Expired
- 1980-01-15 PT PT70698A patent/PT70698A/pt unknown
- 1980-01-15 ES ES487713A patent/ES487713A1/es not_active Expired
- 1980-01-15 AT AT80400050T patent/ATE2253T1/de not_active IP Right Cessation
- 1980-01-15 GR GR60963A patent/GR74394B/el unknown
- 1980-01-15 AU AU54630/80A patent/AU528634B2/en not_active Ceased
- 1980-01-15 DK DK16980A patent/DK16980A/da not_active Application Discontinuation
- 1980-01-15 IL IL59128A patent/IL59128A/xx unknown
- 1980-01-15 EP EP80400050A patent/EP0018857B1/fr not_active Expired
- 1980-01-15 DE DE8080400050T patent/DE3061648D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3061648D1 (en) | 1983-02-24 |
| EP0018857A1 (fr) | 1980-11-12 |
| DK16980A (da) | 1980-10-27 |
| ZA80242B (en) | 1980-12-31 |
| NO794271L (no) | 1980-10-28 |
| AU5463080A (en) | 1980-10-30 |
| IL59128A (en) | 1982-07-30 |
| US4358451A (en) | 1982-11-09 |
| ES487713A1 (es) | 1980-06-16 |
| AU528634B2 (en) | 1983-05-05 |
| FR2455039B1 (cg-RX-API-DMAC7.html) | 1983-05-13 |
| FR2455039A1 (fr) | 1980-11-21 |
| ATE2253T1 (de) | 1983-02-15 |
| CA1129854A (en) | 1982-08-17 |
| IL59128A0 (en) | 1980-05-30 |
| EP0018857B1 (fr) | 1983-01-19 |
| JPS55145689A (en) | 1980-11-13 |
| PT70698A (fr) | 1980-02-01 |
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