ATE2253T1 - Pyrimido und imidazo-pyrido-indol-dione, ihre herstellung und therapeutische verwendung. - Google Patents

Pyrimido und imidazo-pyrido-indol-dione, ihre herstellung und therapeutische verwendung.

Info

Publication number
ATE2253T1
ATE2253T1 AT80400050T AT80400050T ATE2253T1 AT E2253 T1 ATE2253 T1 AT E2253T1 AT 80400050 T AT80400050 T AT 80400050T AT 80400050 T AT80400050 T AT 80400050T AT E2253 T1 ATE2253 T1 AT E2253T1
Authority
AT
Austria
Prior art keywords
alkyl
pyrimido
imidazo
diones
pyrido
Prior art date
Application number
AT80400050T
Other languages
English (en)
Inventor
Istvan Koletar Gabor
Jonathan Frost
Regis Dupont
Patrick Lardenois
Claude Morel
Henry Najer
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of ATE2253T1 publication Critical patent/ATE2253T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT80400050T 1979-04-26 1980-01-15 Pyrimido und imidazo-pyrido-indol-dione, ihre herstellung und therapeutische verwendung. ATE2253T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7910653A FR2455039A1 (fr) 1979-04-26 1979-04-26 Pyrimido et imidazo-pyrido-indole-diones et leur application en therapeutique
EP80400050A EP0018857B1 (de) 1979-04-26 1980-01-15 Pyrimido und Imidazo-pyrido-indol-dione, ihre Herstellung und therapeutische Verwendung

Publications (1)

Publication Number Publication Date
ATE2253T1 true ATE2253T1 (de) 1983-02-15

Family

ID=9224796

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80400050T ATE2253T1 (de) 1979-04-26 1980-01-15 Pyrimido und imidazo-pyrido-indol-dione, ihre herstellung und therapeutische verwendung.

Country Status (15)

Country Link
US (1) US4358451A (de)
EP (1) EP0018857B1 (de)
JP (1) JPS55145689A (de)
AT (1) ATE2253T1 (de)
AU (1) AU528634B2 (de)
CA (1) CA1129854A (de)
DE (1) DE3061648D1 (de)
DK (1) DK16980A (de)
ES (1) ES487713A1 (de)
FR (1) FR2455039A1 (de)
GR (1) GR74394B (de)
IL (1) IL59128A (de)
NO (1) NO794271L (de)
PT (1) PT70698A (de)
ZA (1) ZA80242B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3246932A1 (de) * 1982-12-16 1984-06-20 Schering AG, 1000 Berlin und 4709 Bergkamen Substituierte 5h-pyrimido(5,4-b)indole
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
FR2901795A1 (fr) * 2006-05-30 2007-12-07 Fourtillan Snc Derives de pyrimidino[1',6'-1,2]pyrido[3,4-b]indoles et leur utilisation en therapeutique
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1076114A (en) * 1975-02-10 1980-04-22 Mitsubishi Chemical Industries Limited 1,5-alkylene-3-aryl hydantoin derivatives

Also Published As

Publication number Publication date
AU528634B2 (en) 1983-05-05
IL59128A0 (en) 1980-05-30
ZA80242B (en) 1980-12-31
GR74394B (de) 1984-06-28
FR2455039A1 (fr) 1980-11-21
FR2455039B1 (de) 1983-05-13
EP0018857B1 (de) 1983-01-19
ES487713A1 (es) 1980-06-16
EP0018857A1 (de) 1980-11-12
CA1129854A (en) 1982-08-17
JPS55145689A (en) 1980-11-13
NO794271L (no) 1980-10-28
IL59128A (en) 1982-07-30
US4358451A (en) 1982-11-09
PT70698A (fr) 1980-02-01
DK16980A (da) 1980-10-27
AU5463080A (en) 1980-10-30
DE3061648D1 (en) 1983-02-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee