GR63213B - 4-trifluormethylbenzoic acid derivatives and process of making the same and pharmaceutical compositions containing thereof - Google Patents
4-trifluormethylbenzoic acid derivatives and process of making the same and pharmaceutical compositions containing thereofInfo
- Publication number
- GR63213B GR63213B GR53603A GR770153603A GR63213B GR 63213 B GR63213 B GR 63213B GR 53603 A GR53603 A GR 53603A GR 770153603 A GR770153603 A GR 770153603A GR 63213 B GR63213 B GR 63213B
- Authority
- GR
- Greece
- Prior art keywords
- trifluormethylbenzoic
- making
- same
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- SWKPKONEIZGROQ-UHFFFAOYSA-N 4-trifluoromethylbenzoic acid Chemical class OC(=O)C1=CC=C(C(F)(F)F)C=C1 SWKPKONEIZGROQ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/694,523 US4096252A (en) | 1976-06-10 | 1976-06-10 | 4-Trifluoromethylbenzoic acid derivatives as thromboembolic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR63213B true GR63213B (en) | 1979-10-09 |
Family
ID=24789174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR53603A GR63213B (en) | 1976-06-10 | 1977-06-01 | 4-trifluormethylbenzoic acid derivatives and process of making the same and pharmaceutical compositions containing thereof |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US4096252A (el) |
| JP (1) | JPS5914007B2 (el) |
| AU (3) | AU2588077A (el) |
| BE (1) | BE855588A (el) |
| CA (1) | CA1090705A (el) |
| DE (2) | DE2641556A1 (el) |
| ES (1) | ES459855A1 (el) |
| FI (1) | FI771842A (el) |
| FR (1) | FR2354335A1 (el) |
| GB (1) | GB1588633A (el) |
| GR (1) | GR63213B (el) |
| IE (1) | IE45962B1 (el) |
| NL (1) | NL7706433A (el) |
| PT (1) | PT66637B (el) |
| ZA (1) | ZA773459B (el) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4397790A (en) * | 1980-12-03 | 1983-08-09 | Monsanto Company | Isophosphinolinone derivatives |
| DE3127237A1 (de) * | 1981-07-10 | 1983-01-20 | Hoechst Ag, 6000 Frankfurt | Magenvertraegliche arzneiformen von xanthinderivaten und verfahren zu ihrer herstellung |
| US4766389A (en) * | 1986-09-03 | 1988-08-23 | Extrude Hone Corporation | Capacitor array sensors tactile and proximity sensing and methods of use thereof |
| GB8927503D0 (en) * | 1989-12-04 | 1990-02-07 | Kronem Systems Inc | Enzyme-amplified lanthanide chelate luminescence |
| IT1243410B (it) * | 1990-12-17 | 1994-06-10 | Donegani Guido Ist | Procedimento per la funzionalizzazione di trifluorometilbenzeni |
| ES2136581B1 (es) * | 1998-05-27 | 2000-09-16 | Uriach & Cia Sa J | Uso de derivados del acido-2-hidroxi-4-trifluorometilbenzoico para la preparacion de medicamentos utiles para inhibir el factor de transcripcion nuclear nf-kb. |
| US6509377B1 (en) * | 1999-05-26 | 2003-01-21 | J. Uriach & Cia, S.A. | Use of a 2-hydroxy-4-trifluoromethylbenzoic acid derivatives as inhibitors of the activation of the nuclear transcription factor NF-κB |
| ES2154242B1 (es) * | 1999-09-03 | 2001-10-16 | Uriach & Cia Sa J | Nuevos sistemas polimericos biocompatibles portadores de triflusal o htb. |
| ES2190373B1 (es) * | 2001-12-07 | 2004-10-16 | J. URIACH & CIA, S.A. | Uso del acido 2-hidroxi- o 2-acetiloxi-4-trifluorometilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero. |
| KR100503267B1 (ko) * | 2002-09-17 | 2005-07-22 | (주)리드젠 | 2-아세틸옥시-4-트리플루오로메틸 벤조산의 제조 방법 |
| CN1308282C (zh) * | 2005-01-11 | 2007-04-04 | 山东师范大学 | 一种4－三氟甲基乙酰水杨酸的催化合成方法 |
| WO2009100534A1 (en) * | 2008-02-14 | 2009-08-20 | Kardiatech, Inc. | Combination therapy to treat vascular disorders |
| US20100069326A1 (en) * | 2008-02-14 | 2010-03-18 | Wasimul Haque | Combination Therapies to Treat Cardio- and Cerebro-Vascular Disorders |
| CN101695496A (zh) * | 2009-10-15 | 2010-04-21 | 苏春华 | 一种含有三氟柳和氯吡格雷的药物组合物 |
| ES2389348B1 (es) | 2011-04-05 | 2013-09-23 | Simbec Ibérica Sl | Polvo compuesto de triflusal, uso del mismo para granulados, comprimidos o sobres, procedimiento para la preparación de dicho polvo compuesto y uso de una o mas ciclodextrinas para estabilizar el triflusal. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE25085E (en) * | 1961-11-21 | Therapeutic use of ortho-carboxy-sub | ||
| CA621838A (en) * | 1961-06-13 | E. Fancher Otis | Salts of phosphosalicylic acid | |
| FR1174923A (fr) * | 1956-05-10 | 1959-03-18 | Ciba Geigy | Procédé de préparation de dérivés phosphorylés d'acides organiques hydroxylés |
| US3019253A (en) * | 1958-05-15 | 1962-01-30 | Pennsalt Chemicals Corp | Acetyl-4-trifluoromethyl salicylic acid |
-
1976
- 1976-06-10 US US05/694,523 patent/US4096252A/en not_active Expired - Lifetime
- 1976-09-15 DE DE19762641556 patent/DE2641556A1/de active Granted
- 1976-09-15 DE DE2661085A patent/DE2661085C2/de not_active Expired
- 1976-12-30 US US05/755,851 patent/US4110442A/en not_active Expired - Lifetime
-
1977
- 1977-06-01 GR GR53603A patent/GR63213B/el unknown
- 1977-06-03 CA CA279,838A patent/CA1090705A/en not_active Expired
- 1977-06-06 PT PT66637A patent/PT66637B/pt unknown
- 1977-06-07 ES ES459855A patent/ES459855A1/es not_active Expired
- 1977-06-07 AU AU25880/77A patent/AU2588077A/en not_active Expired - Fee Related
- 1977-06-08 ZA ZA00773459A patent/ZA773459B/xx unknown
- 1977-06-09 FR FR7717707A patent/FR2354335A1/fr active Granted
- 1977-06-10 NL NL7706433A patent/NL7706433A/xx not_active Application Discontinuation
- 1977-06-10 GB GB24415/77A patent/GB1588633A/en not_active Expired
- 1977-06-10 BE BE178361A patent/BE855588A/xx not_active IP Right Cessation
- 1977-06-10 JP JP52068731A patent/JPS5914007B2/ja not_active Expired
- 1977-06-10 IE IE1197/77A patent/IE45962B1/en not_active IP Right Cessation
- 1977-06-10 FI FI771842A patent/FI771842A/fi not_active Application Discontinuation
-
1986
- 1986-02-27 AU AU54156/86A patent/AU5415686A/en not_active Abandoned
-
1988
- 1988-12-22 AU AU27477/88A patent/AU2747788A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA1090705A (en) | 1980-12-02 |
| IE45962B1 (en) | 1983-01-12 |
| JPS5914007B2 (ja) | 1984-04-02 |
| US4110442A (en) | 1978-08-29 |
| PT66637B (en) | 1978-11-09 |
| ES459855A1 (es) | 1978-04-01 |
| AU5415686A (en) | 1986-07-31 |
| DE2641556A1 (de) | 1977-12-29 |
| US4096252A (en) | 1978-06-20 |
| DE2661085C2 (el) | 1988-04-07 |
| GB1588633A (en) | 1981-04-29 |
| IE45962L (en) | 1977-12-10 |
| NL7706433A (nl) | 1977-12-13 |
| FR2354335B1 (el) | 1982-11-12 |
| FI771842A (el) | 1977-12-11 |
| ZA773459B (en) | 1978-05-30 |
| FR2354335A1 (fr) | 1978-01-06 |
| AU2588077A (en) | 1978-12-14 |
| PT66637A (en) | 1977-07-01 |
| JPS52156831A (en) | 1977-12-27 |
| BE855588A (fr) | 1977-10-03 |
| DE2641556C2 (el) | 1988-12-29 |
| AU2747788A (en) | 1989-04-27 |
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