GR35150B - Τελειοποιησεις εις η εν σχεσει προς μεθοδον παρασκευης αντιβιοτικων. - Google Patents
Τελειοποιησεις εις η εν σχεσει προς μεθοδον παρασκευης αντιβιοτικων.Info
- Publication number
- GR35150B GR35150B GR670135150A GR670135150A GR35150B GR 35150 B GR35150 B GR 35150B GR 670135150 A GR670135150 A GR 670135150A GR 670135150 A GR670135150 A GR 670135150A GR 35150 B GR35150 B GR 35150B
- Authority
- GR
- Greece
- Prior art keywords
- reaction
- salt
- acid
- acid addition
- acylamidocef
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229940088710 antibiotic agent Drugs 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 6
- 238000006243 chemical reaction Methods 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 5
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 4
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N thiocyanic acid Chemical compound SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 229960003237 betaine Drugs 0.000 abstract 2
- TWBYWOBDOCUKOW-UHFFFAOYSA-N isonicotinic acid Chemical compound OC(=O)C1=CC=NC=C1 TWBYWOBDOCUKOW-UHFFFAOYSA-N 0.000 abstract 2
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 229910000043 hydrogen iodide Inorganic materials 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000012071 phase Substances 0.000 abstract 1
- 239000000049 pigment Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000012429 reaction media Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1571966A GB1171603A (en) | 1966-04-07 | 1966-04-07 | Improvements in or relating to cephalosporins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR35150B true GR35150B (el) | 1968-08-21 |
Family
ID=10064258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR670135150A GR35150B (el) | 1966-04-07 | 1967-04-04 | Τελειοποιησεις εις η εν σχεσει προς μεθοδον παρασκευης αντιβιοτικων. |
Country Status (10)
| Country | Link |
|---|---|
| AT (1) | AT287189B (da) |
| BE (1) | BE696775A (da) |
| CH (1) | CH504472A (da) |
| DE (1) | DE1695015C3 (da) |
| DK (1) | DK136609C (da) |
| ES (1) | ES339028A1 (da) |
| GB (1) | GB1171603A (da) |
| GR (1) | GR35150B (da) |
| NL (1) | NL6704945A (da) |
| SE (1) | SE370080B (da) |
-
1966
- 1966-04-07 GB GB1571966A patent/GB1171603A/en not_active Expired
-
1967
- 1967-04-04 GR GR670135150A patent/GR35150B/el unknown
- 1967-04-07 NL NL6704945A patent/NL6704945A/xx unknown
- 1967-04-07 ES ES339028A patent/ES339028A1/es not_active Expired
- 1967-04-07 CH CH494767A patent/CH504472A/de not_active IP Right Cessation
- 1967-04-07 DE DE1967G0049776 patent/DE1695015C3/de not_active Expired
- 1967-04-07 BE BE696775D patent/BE696775A/xx not_active IP Right Cessation
- 1967-04-07 DK DK195867A patent/DK136609C/da not_active IP Right Cessation
- 1967-04-07 AT AT333467A patent/AT287189B/de active
- 1967-04-07 SE SE489467A patent/SE370080B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1695015B2 (de) | 1977-09-22 |
| DE1695015A1 (de) | 1972-03-09 |
| AT287189B (de) | 1971-01-11 |
| DK136609C (da) | 1978-04-10 |
| NL6704945A (da) | 1967-10-09 |
| GB1171603A (en) | 1969-11-26 |
| BE696775A (da) | 1967-10-09 |
| DE1695015C3 (de) | 1978-05-03 |
| CH504472A (de) | 1971-03-15 |
| DK136609B (da) | 1977-10-31 |
| ES339028A1 (es) | 1968-07-01 |
| SE370080B (da) | 1974-09-30 |
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