GR34667B - Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων. - Google Patents
Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων.Info
- Publication number
- GR34667B GR34667B GR670134667A GR670134667A GR34667B GR 34667 B GR34667 B GR 34667B GR 670134667 A GR670134667 A GR 670134667A GR 670134667 A GR670134667 A GR 670134667A GR 34667 B GR34667 B GR 34667B
- Authority
- GR
- Greece
- Prior art keywords
- cat
- alkylamino
- alkoxy
- preparation
- substituted
- Prior art date
Links
- 150000001735 carboxylic acids Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- -1 (5-trifluoromethylphenoxy)(4-chlorophenyl)acetyl halide Chemical class 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/50—Y being a hydrogen or an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
- C07C275/10—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58393766A | 1966-10-03 | 1966-10-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR34667B true GR34667B (el) | 1968-06-05 |
Family
ID=24335223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR670134667A GR34667B (el) | 1966-10-03 | 1967-09-22 | Μεθοδος δια την παρασκευην εστερων και αμιδιων των καρβοξυλικων οξεων. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3517050A (cg-RX-API-DMAC7.html) |
| AT (2) | AT279590B (cg-RX-API-DMAC7.html) |
| BE (1) | BE704574A (cg-RX-API-DMAC7.html) |
| BR (1) | BR6793319D0 (cg-RX-API-DMAC7.html) |
| CH (1) | CH512422A (cg-RX-API-DMAC7.html) |
| CS (1) | CS170496B2 (cg-RX-API-DMAC7.html) |
| CY (1) | CY650A (cg-RX-API-DMAC7.html) |
| DE (1) | DE1643460A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK120955B (cg-RX-API-DMAC7.html) |
| ES (1) | ES345582A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI48064C (cg-RX-API-DMAC7.html) |
| FR (2) | FR1573841A (cg-RX-API-DMAC7.html) |
| GB (1) | GB1182007A (cg-RX-API-DMAC7.html) |
| GR (1) | GR34667B (cg-RX-API-DMAC7.html) |
| MY (1) | MY7300079A (cg-RX-API-DMAC7.html) |
| NL (1) | NL149484B (cg-RX-API-DMAC7.html) |
| NO (1) | NO121787B (cg-RX-API-DMAC7.html) |
| SE (1) | SE332182B (cg-RX-API-DMAC7.html) |
| YU (1) | YU32921B (cg-RX-API-DMAC7.html) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3923855A (en) * | 1972-07-13 | 1975-12-02 | Merck & Co Inc | 2-sulfonyloxyethyl 3-trifluoromethylphenoxy-4{40 -chlorophenyl acetate |
| US4110351A (en) * | 1973-04-02 | 1978-08-29 | Richardson-Merrell Inc. | Hypolipidemic agents RO- or RS- substituted furoic acids, esters and salts |
| DK115374A (cg-RX-API-DMAC7.html) | 1974-03-04 | 1975-11-03 | Byk Gulden Lomberg Chem Fab | |
| IL48707A0 (en) * | 1974-12-30 | 1976-02-29 | Synthelabo | Novel phenylacetic acid derivatives,their preparation and pharmaceutical compositions containing them |
| FR2424247A2 (fr) * | 1978-04-27 | 1979-11-23 | Science Union & Cie | Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention |
| US4250191A (en) * | 1978-11-30 | 1981-02-10 | Edwards K David | Preventing renal failure |
| US7576131B2 (en) * | 1999-06-04 | 2009-08-18 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| US6262118B1 (en) * | 1999-06-04 | 2001-07-17 | Metabolex, Inc. | Use of (-) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes and hyperlipidemia |
| US6624194B1 (en) | 1999-06-04 | 2003-09-23 | Metabolex, Inc. | Use of (−) (3-trihalomethylphenoxy) (4-halophenyl) acetic acid derivatives for treatment of insulin resistance, type 2 diabetes, hyperlipidemia and hyperuricemia |
| JP2004521124A (ja) * | 2001-02-09 | 2004-07-15 | メルク エンド カムパニー インコーポレーテッド | 糖尿病および脂質障害用の２−アリールオキシ−２−アリールアルカン酸類 |
| US7199259B2 (en) * | 2003-06-20 | 2007-04-03 | Metabolex, Inc. | Resolution of α-(phenoxy)phenylacetic acid derivatives |
| CN100525757C (zh) * | 2003-06-20 | 2009-08-12 | 麦它波莱克斯股份有限公司 | α-(苯氧基)苯乙酸衍生物的拆分 |
| MXPA05013981A (es) * | 2003-06-20 | 2006-03-02 | Metabolex Inc | Resolucion de derivados de acido a- (fenoxi) fenilacetico. |
| USD492579S1 (en) | 2003-10-15 | 2004-07-06 | The Gates Corporation | Pulley |
| CN1922143A (zh) | 2004-02-18 | 2007-02-28 | 麦它波莱克斯股份有限公司 | 作为抗糖尿病药的α－(三氟甲基－取代的芳氧基、芳基氨基、芳硫基或芳基甲基)－三氟甲基－取代的苯乙酸和衍生物 |
| BRPI0511510A (pt) * | 2004-05-25 | 2007-12-26 | Metabolex Inc | composto, sais, solvatos, hidratos e pró-drogas farmaceuticamente aceitáveis do mesmo, composição, e, métodos para modular um receptor ativado com proliferador de peroxisoma, para tratar doença, para modular resistência à insulina, para tratar um ou mais fatores de risco para doença cardiovascular, para diminuir nìveis de fibrinogênio, para diminiuir ldlc, para suprimir apetite, e para modular nìveis de leptina em um indivìduo |
| EP1749000A4 (en) * | 2004-05-25 | 2009-12-30 | Metabolex Inc | BICYCLIC SUBSTITUTED TRIAZOLE AS PPAR MODULATORS AND METHOD FOR THE PRODUCTION THEREOF |
| US8288438B2 (en) | 2005-03-21 | 2012-10-16 | Metabolex, Inc. | Methods for avoiding edema in the treatment or prevention of PPARγ-responsive diseases, including cancer |
| US7432394B2 (en) * | 2005-09-23 | 2008-10-07 | Metabolex, Inc. | Resolution of α-(phenoxy) phenylacetic acid derivatives with naphthyl-alkylamines |
| US7714131B2 (en) * | 2005-09-23 | 2010-05-11 | Metabolex, Inc. | Process for the stereoselective preparation of (−)-halofenate and derivatives thereof |
| WO2009121940A1 (en) * | 2008-04-03 | 2009-10-08 | Janssen Pharmaceutica Nv | Process for the preparation of (-)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester |
| US9023856B2 (en) | 2011-11-04 | 2015-05-05 | Cymabay Therapeutics, Inc. | Methods for treating hyperuricemia in patients with gout using halofenate or halogenic acid and a second urate-lowering agent |
| US9060987B2 (en) | 2011-11-04 | 2015-06-23 | Cymabay Therapeutics, Inc. | Methods for treating gout flares |
| EP2847152A4 (en) * | 2012-05-10 | 2016-03-23 | Cellix Bio Private Ltd | COMPOSITIONS AND METHOD FOR THE TREATMENT OF METABOLIC SYNDROME |
| CA2901353A1 (en) * | 2013-01-18 | 2014-07-24 | Cymabay Therapeutics, Inc. | Dcc mediated coupling for halofenate manufacture |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES251290A1 (es) * | 1958-08-21 | 1960-04-01 | Parke Davis & Co | Un procedimiento para la producciën de alcohilaminas arilsustituidas |
-
1966
- 1966-10-03 US US583937A patent/US3517050A/en not_active Expired - Lifetime
-
1967
- 1967-09-14 NL NL676712584A patent/NL149484B/xx unknown
- 1967-09-20 CS CS6703A patent/CS170496B2/cs unknown
- 1967-09-20 NO NO169792A patent/NO121787B/no unknown
- 1967-09-21 YU YU1851/67A patent/YU32921B/xx unknown
- 1967-09-22 FI FI672535A patent/FI48064C/fi active
- 1967-09-22 GR GR670134667A patent/GR34667B/el unknown
- 1967-09-26 DK DK477867AA patent/DK120955B/da unknown
- 1967-09-26 BR BR193319/67A patent/BR6793319D0/pt unknown
- 1967-09-27 SE SE13273/67A patent/SE332182B/xx unknown
- 1967-09-27 GB GB44020/67A patent/GB1182007A/en not_active Expired
- 1967-09-29 AT AT888067A patent/AT279590B/de not_active IP Right Cessation
- 1967-09-29 ES ES345582A patent/ES345582A1/es not_active Expired
- 1967-10-02 DE DE19671643460 patent/DE1643460A1/de not_active Withdrawn
- 1967-10-02 BE BE704574D patent/BE704574A/xx unknown
- 1967-10-02 CH CH1369767A patent/CH512422A/de not_active IP Right Cessation
- 1967-10-02 FR FR1573841D patent/FR1573841A/fr not_active Expired
- 1967-10-03 AT AT03550/69A patent/AT282617B/de not_active IP Right Cessation
- 1967-12-29 FR FR134252A patent/FR8372M/fr not_active Expired
-
1972
- 1972-07-12 CY CY65072A patent/CY650A/xx unknown
-
1973
- 1973-12-31 MY MY197379A patent/MY7300079A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1643460A1 (de) | 1971-01-28 |
| NL149484B (nl) | 1976-05-17 |
| ES345582A1 (es) | 1970-02-01 |
| CY650A (en) | 1972-07-12 |
| FR8372M (cg-RX-API-DMAC7.html) | 1971-02-22 |
| GB1182007A (en) | 1970-02-25 |
| FR1573841A (cg-RX-API-DMAC7.html) | 1969-07-11 |
| FI48064C (fi) | 1974-06-10 |
| DK120955B (da) | 1971-08-09 |
| AT279590B (de) | 1970-03-10 |
| BR6793319D0 (pt) | 1973-05-24 |
| YU185167A (en) | 1975-06-30 |
| CH512422A (de) | 1971-09-15 |
| CS170496B2 (cg-RX-API-DMAC7.html) | 1976-08-27 |
| NO121787B (cg-RX-API-DMAC7.html) | 1971-04-13 |
| MY7300079A (en) | 1973-12-31 |
| YU32921B (en) | 1975-12-31 |
| US3517050A (en) | 1970-06-23 |
| NL6712584A (cg-RX-API-DMAC7.html) | 1968-04-04 |
| BE704574A (cg-RX-API-DMAC7.html) | 1968-04-02 |
| FI48064B (cg-RX-API-DMAC7.html) | 1974-02-28 |
| SE332182B (cg-RX-API-DMAC7.html) | 1971-02-01 |
| AT282617B (de) | 1970-07-10 |
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