GR3035603T3 - Mammals lacking expression of cd28 transgenic - Google Patents
Mammals lacking expression of cd28 transgenicInfo
- Publication number
- GR3035603T3 GR3035603T3 GR20010400449T GR20010400449T GR3035603T3 GR 3035603 T3 GR3035603 T3 GR 3035603T3 GR 20010400449 T GR20010400449 T GR 20010400449T GR 20010400449 T GR20010400449 T GR 20010400449T GR 3035603 T3 GR3035603 T3 GR 3035603T3
- Authority
- GR
- Greece
- Prior art keywords
- transgenic
- lacking expression
- mammals
- mammals lacking
- isoform
- Prior art date
Links
- 241000124008 Mammalia Species 0.000 title abstract 4
- 230000009261 transgenic effect Effects 0.000 title 1
- 108010029485 Protein Isoforms Proteins 0.000 abstract 2
- 102000001708 Protein Isoforms Human genes 0.000 abstract 2
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 abstract 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 abstract 1
- 108700019146 Transgenes Proteins 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70589—CD45
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0325—Animal model for autoimmune diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0381—Animal model for diseases of the hematopoietic system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Environmental Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Packaging For Recording Disks (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6776793A | 1993-05-26 | 1993-05-26 | |
PCT/US1994/005913 WO1994028123A1 (en) | 1993-05-26 | 1994-05-25 | Mammals lacking expression of cd28 transgenic |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3035603T3 true GR3035603T3 (en) | 2001-06-29 |
Family
ID=22078279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20010400449T GR3035603T3 (en) | 1993-05-26 | 2001-03-20 | Mammals lacking expression of cd28 transgenic |
Country Status (9)
Country | Link |
---|---|
US (3) | US6664107B1 (el) |
EP (1) | EP0701607B1 (el) |
AT (1) | ATE198621T1 (el) |
AU (1) | AU685811B2 (el) |
DE (1) | DE69426564T2 (el) |
ES (1) | ES2155474T3 (el) |
GR (1) | GR3035603T3 (el) |
PT (1) | PT701607E (el) |
WO (1) | WO1994028123A1 (el) |
Families Citing this family (87)
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US6264915B1 (en) | 1992-09-13 | 2001-07-24 | The President And Fellows Of Harvard College | Process for detecting potential carcinogens |
US6025183A (en) * | 1994-02-28 | 2000-02-15 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Transgenic animal assay system for anti-cholinesterase substances |
WO1995034640A1 (en) * | 1994-06-13 | 1995-12-21 | Henry Ford Health System | A novel neuronal-neonatal gene: neuronatin |
HUP9801629A3 (en) * | 1995-02-09 | 2000-10-30 | Icn Pharmaceuticals Inc Costa | Methods and compositions for regulation of cd28 expression |
US5777093A (en) * | 1995-05-16 | 1998-07-07 | Ramot-University Authority For Applied Research & Industrial Development Ltd. | cDNAs associated with ataxia-telangiectasia |
US5728807A (en) * | 1995-05-16 | 1998-03-17 | Ramot-University Authority For Applied Research And Industrial Development, Ltd. | Mutated proteins associated with ataxia-telangiectasia |
US5858661A (en) | 1995-05-16 | 1999-01-12 | Ramot-University Authority For Applied Research And Industrial Development | Ataxia-telangiectasia gene and its genomic organization |
US6140309A (en) * | 1996-03-12 | 2000-10-31 | University Of South Florida | Vasoactive effects and free radical generation by β-amyloid peptides |
US20060021070A1 (en) * | 1996-04-01 | 2006-01-26 | University of Massachusetts, a Public Institution of Higher Education of the Commonwealth of MA | Production of chimeric bovine or porcine animals using cultured inner cell mass |
US7223849B1 (en) | 1996-07-01 | 2007-05-29 | Genesense Technologies Inc. | Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth |
US7390891B1 (en) | 1996-11-15 | 2008-06-24 | Amgen Inc. | Polynucleotides encoding a telomerase component TP2 |
US5919656A (en) * | 1996-11-15 | 1999-07-06 | Amgen Canada Inc. | Genes encoding telomerase protein 1 |
AU4964097A (en) * | 1996-11-15 | 1998-06-10 | Sumitomo Pharmaceuticals Company, Limited | Novel semaphorin genes (i) |
US7071171B1 (en) | 1996-12-20 | 2006-07-04 | Board Of Regents The University Of Texas System | Unique dendritic cell-associated c-type lectins, dectin-1 and dectin-2 compositions and uses thereof |
US6046158A (en) * | 1996-12-20 | 2000-04-04 | Board Of Regents The University Of Texas Systems | Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof |
US5817912A (en) * | 1997-01-16 | 1998-10-06 | B.M.R.A. Corporation B.V. | Transgenic mice with disrupted NPY Y1 receptor genes |
AU9110798A (en) | 1997-08-21 | 1999-03-08 | Quark Biotech, Inc. | Hypoxia-regulated genes |
US7973156B2 (en) | 1997-08-21 | 2011-07-05 | Quark Pharmaceuticals Inc. | Hypoxia-regulated genes |
WO1999035279A1 (en) | 1998-01-12 | 1999-07-15 | Georgetown University Medical Center | G protein-related kinase mutants in essential hypertension |
US6893838B1 (en) | 1998-04-07 | 2005-05-17 | Genetics Institute Llc | DADD, death activator death domain protein |
US6492138B1 (en) * | 1998-05-21 | 2002-12-10 | Amgen Canada Inc. | Polynucleotides encoding a novel SHC-binding protein |
US5973119A (en) * | 1998-06-05 | 1999-10-26 | Amgen Inc. | Cyclin E genes and proteins |
US6344541B1 (en) | 1998-09-25 | 2002-02-05 | Amgen Inc. | DKR polypeptides |
WO2000058479A1 (en) | 1999-03-26 | 2000-10-05 | Amgen Inc. | Beta secretase genes and polypeptides |
ATE377077T1 (de) | 1999-04-28 | 2007-11-15 | Genetics Inst Llc | Humane gil-19/ae289 proteine und dafür kodierende polynukleotide |
US6787318B1 (en) | 1999-06-01 | 2004-09-07 | Roskamp Research Institute, Llc | Assay for evaluating the therapeutic effectiveness of agents in reducing Alzheimer's disease pathology |
US6875582B1 (en) | 1999-08-19 | 2005-04-05 | Omniscience Pharmaceuticals, Inc. | Methods and targets of antibiotic resistance |
US7459540B1 (en) | 1999-09-07 | 2008-12-02 | Amgen Inc. | Fibroblast growth factor-like polypeptides |
US7408047B1 (en) * | 1999-09-07 | 2008-08-05 | Amgen Inc. | Fibroblast growth factor-like polypeptides |
US6900043B1 (en) | 1999-09-21 | 2005-05-31 | Amgen Inc. | Phosphatases which activate map kinase pathways |
US7638324B2 (en) | 2000-04-06 | 2009-12-29 | Burnham Institute For Medical Research | Bcl-G polypeptides, encoding nucleic acids and methods of use |
US20040034192A1 (en) * | 2000-01-06 | 2004-02-19 | Seishi Kato | Human proteins having hyprophobic domains and dnas encoding these proteins |
WO2001053323A2 (en) | 2000-01-24 | 2001-07-26 | Ramot University Authority For Applied Research & Industrial Development Ltd. | Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby |
TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
EP1276500B1 (en) | 2000-03-13 | 2011-06-08 | Cornell Research Foundation, Inc. | Blocking leukocyte emigration and inflammation by interfering with cd99/hec2 |
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US7514239B2 (en) | 2000-03-28 | 2009-04-07 | Amgen Inc. | Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof |
US6686180B2 (en) * | 2000-04-04 | 2004-02-03 | Baxter International Inc. | Method for the production of bacterial toxins |
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ES2317917T3 (es) | 2000-06-28 | 2009-05-01 | Amgen Inc. | Moleculas de receptor de linfopoyetina estromal timica y sus usos de las mismas. |
HUP0300810A2 (hu) | 2000-07-20 | 2003-08-28 | M.G.V.S. Ltd. | Mesterséges értranszplantátum, valamint ennek létrehozása és alkalmazása |
US20040037828A1 (en) | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
US20050239125A1 (en) * | 2000-09-06 | 2005-10-27 | Hodge Timothy A | Methods for genotype screening |
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US7737124B2 (en) | 2001-09-13 | 2010-06-15 | California Institute Of Technology | Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell |
US7195916B2 (en) * | 2001-09-13 | 2007-03-27 | California Institute Of Technology | Method for expression of small antiviral RNA molecules within a cell |
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US20040023910A1 (en) * | 2001-09-28 | 2004-02-05 | Zhiming Zhang | Use of cyr61 in the treatment and diagnosis of human uterine leiomyomas |
AU2002358947A1 (en) | 2001-12-05 | 2003-06-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nanoparticles containing polymeric nucleic acid homologs, pharmaceutical compositions and articles of manufacture containing same and methods of use thereof |
EP1329506A1 (en) * | 2002-01-18 | 2003-07-23 | Cypro S.A. | Method to quantify in vivo RNA levels |
US6992176B2 (en) | 2002-02-13 | 2006-01-31 | Technion Research & Development Foundation Ltd. | Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease |
US7662924B2 (en) * | 2002-02-22 | 2010-02-16 | The Board Of Trustees Of The University Of Illinois | Beta chain-associated regulator of apoptosis |
AU2003217693A1 (en) * | 2002-02-22 | 2003-09-09 | Board Of Trustees Of The University Of Illinois | Beta chain-associated regulator of apoptosis |
CN103275058B (zh) | 2003-08-06 | 2016-02-24 | 西诺米克斯公司 | 调味剂、味道调节剂、促味剂、味觉增强剂、鲜味剂或甜味剂和/或增强剂及其用途 |
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CN101437539B (zh) * | 2005-07-05 | 2013-10-02 | 康奈尔研究基金会(有限公司) | 通过干扰cd99l2阻断白细胞迁出和炎症 |
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US8129334B2 (en) | 2006-03-31 | 2012-03-06 | The Regents Of The University Of California | Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory |
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US8153116B2 (en) | 2006-07-11 | 2012-04-10 | University Of Connecticut | Use of conditional plasmodium strains lacking an essential gene in malaria vaccination |
US8128921B2 (en) * | 2006-07-11 | 2012-03-06 | University Of Connecticut | Use of conditional plasmodium strains lacking nutrient transporters in malaria vaccination |
US8454948B2 (en) | 2006-09-14 | 2013-06-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
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US7943590B2 (en) | 2007-03-16 | 2011-05-17 | Multi-Gene Vascular Systems Ltd. | Compositions and methods for treating ophthalmic disorders |
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US8093043B2 (en) * | 2008-06-04 | 2012-01-10 | New York University | β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis |
EP2324044A4 (en) | 2008-08-04 | 2012-04-25 | Univ Miami | STING (INTERFERON GENE STIMULATOR), A REGULATOR OF INDIAN IMMUNE RESPONSES |
EA201990619A1 (ru) | 2008-10-10 | 2019-07-31 | Амген Инк. | Fgf21 мутанты и их применение |
AU2010246038A1 (en) | 2009-05-05 | 2011-12-01 | Amgen Inc. | FGF21 mutants and uses thereof |
US8188040B2 (en) | 2009-05-05 | 2012-05-29 | Amgen Inc. | FGF21 mutants and uses thereof |
AU2010262927A1 (en) * | 2009-06-17 | 2012-01-19 | Amgen Inc. | Chimeric FGF19 polypeptides and uses thereof |
AU2010326024A1 (en) * | 2009-12-02 | 2012-07-05 | Amgen Inc. | Binding proteins that bind to human FGFR1c, human beta-Klotho and both human FGFR1c and human beta-Klotho |
UA109888C2 (uk) | 2009-12-07 | 2015-10-26 | ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ | |
CA2796055A1 (en) | 2010-04-15 | 2011-10-20 | Amgen Inc. | Human fgf receptor and .beta.-klotho binding proteins |
EP2582396A4 (en) | 2010-06-15 | 2014-01-01 | Medgenics Medical Israel Ltd | REMEDY FORMULATIONS WITH LONG-TERM EFFECT |
WO2013091130A1 (zh) * | 2011-12-19 | 2013-06-27 | 中国农业大学 | 猪cd28受体,编码其的基因及其应用 |
WO2015059701A1 (en) | 2013-10-24 | 2015-04-30 | Medgenics Medical Israel Ltd. | Micro-organs providing sustained delivery of a therapeutic polypeptide and methods of use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2235992A (en) | 1991-06-14 | 1993-01-12 | Genpharm International, Inc. | Transgenic immunodeficient non-human animals |
AU2661692A (en) | 1991-09-19 | 1993-04-27 | President And Fellows Of Harvard College | Transgenic mhc class i and class ii antigen-deficient mammals |
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1994
- 1994-02-02 US US08/191,225 patent/US6664107B1/en not_active Expired - Fee Related
- 1994-05-25 PT PT94917481T patent/PT701607E/pt unknown
- 1994-05-25 EP EP94917481A patent/EP0701607B1/en not_active Expired - Lifetime
- 1994-05-25 AT AT94917481T patent/ATE198621T1/de not_active IP Right Cessation
- 1994-05-25 WO PCT/US1994/005913 patent/WO1994028123A1/en active IP Right Grant
- 1994-05-25 AU AU69187/94A patent/AU685811B2/en not_active Ceased
- 1994-05-25 ES ES94917481T patent/ES2155474T3/es not_active Expired - Lifetime
- 1994-05-25 DE DE69426564T patent/DE69426564T2/de not_active Expired - Fee Related
-
1995
- 1995-05-26 US US08/451,691 patent/US5557032A/en not_active Expired - Fee Related
- 1995-09-14 US US08/528,363 patent/US5616491A/en not_active Expired - Lifetime
-
2001
- 2001-03-20 GR GR20010400449T patent/GR3035603T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69426564D1 (de) | 2001-02-15 |
US5557032A (en) | 1996-09-17 |
AU685811B2 (en) | 1998-01-29 |
EP0701607A1 (en) | 1996-03-20 |
US5616491A (en) | 1997-04-01 |
WO1994028123A1 (en) | 1994-12-08 |
US6664107B1 (en) | 2003-12-16 |
AU6918794A (en) | 1994-12-20 |
ES2155474T3 (es) | 2001-05-16 |
EP0701607B1 (en) | 2001-01-10 |
DE69426564T2 (de) | 2001-05-31 |
PT701607E (pt) | 2001-05-31 |
ATE198621T1 (de) | 2001-01-15 |
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