GR3034079T3 - Method for preparing 3-amino-2-chloro-4-alkylpyridine or -4-arylpyridine. - Google Patents
Method for preparing 3-amino-2-chloro-4-alkylpyridine or -4-arylpyridine.Info
- Publication number
- GR3034079T3 GR3034079T3 GR20000401771T GR20000401771T GR3034079T3 GR 3034079 T3 GR3034079 T3 GR 3034079T3 GR 20000401771 T GR20000401771 T GR 20000401771T GR 20000401771 T GR20000401771 T GR 20000401771T GR 3034079 T3 GR3034079 T3 GR 3034079T3
- Authority
- GR
- Greece
- Prior art keywords
- pct
- chloro
- amino
- preparing
- arylpyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4341033 | 1993-12-02 | ||
| PCT/EP1994/003988 WO1995015314A1 (de) | 1993-12-02 | 1994-12-01 | Verfahren zur herstellung von 3-amino-2-chlor-4-alkyl- bzw. 4-aryl-pyridin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3034079T3 true GR3034079T3 (en) | 2000-11-30 |
Family
ID=6503969
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20000401771T GR3034079T3 (en) | 1993-12-02 | 2000-07-31 | Method for preparing 3-amino-2-chloro-4-alkylpyridine or -4-arylpyridine. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5686618A (el) |
| EP (1) | EP0682655B1 (el) |
| JP (1) | JP3516454B2 (el) |
| AT (1) | ATE192437T1 (el) |
| CA (1) | CA2155214C (el) |
| DE (2) | DE4442808A1 (el) |
| DK (1) | DK0682655T3 (el) |
| ES (1) | ES2147601T3 (el) |
| GR (1) | GR3034079T3 (el) |
| PT (1) | PT682655E (el) |
| WO (1) | WO1995015314A1 (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136982A (en) * | 1999-01-22 | 2000-10-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Synthesis of 3-amino-2-chloro-4-methylpyridine from acetone and ethyl cyanoacetate |
| EP1064265B8 (en) * | 1999-01-22 | 2004-10-13 | Boehringer Ingelheim Pharmaceuticals Inc. | Synthesis of 3-amino-2-chloro-4-methylpyridine from malononitrile and acetone |
| US6399781B1 (en) | 2000-10-10 | 2002-06-04 | Boehringer Ingelheim Chemicals, Inc. | Process for making 3-amino-2-chloro-4-methylpyridine |
| CN114835714A (zh) * | 2022-04-01 | 2022-08-02 | 上海蓝乐鸟实业有限公司 | 一种托法替尼的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200522A (en) * | 1991-06-11 | 1993-04-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for preparing 3-amino-2-chloro-4-alkylpyridines |
| AU652656B2 (en) * | 1991-06-11 | 1994-09-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the preparation of 3-amino-2-chloro-4-alkylpyridines |
-
1994
- 1994-12-01 WO PCT/EP1994/003988 patent/WO1995015314A1/de active IP Right Grant
- 1994-12-01 JP JP51539895A patent/JP3516454B2/ja not_active Expired - Lifetime
- 1994-12-01 US US08/495,551 patent/US5686618A/en not_active Expired - Lifetime
- 1994-12-01 CA CA002155214A patent/CA2155214C/en not_active Expired - Lifetime
- 1994-12-01 DE DE4442808A patent/DE4442808A1/de not_active Ceased
- 1994-12-01 EP EP95902106A patent/EP0682655B1/de not_active Expired - Lifetime
- 1994-12-01 DK DK95902106T patent/DK0682655T3/da active
- 1994-12-01 ES ES95902106T patent/ES2147601T3/es not_active Expired - Lifetime
- 1994-12-01 DE DE59409324T patent/DE59409324D1/de not_active Expired - Lifetime
- 1994-12-01 PT PT95902106T patent/PT682655E/pt unknown
- 1994-12-01 AT AT95902106T patent/ATE192437T1/de active
-
2000
- 2000-07-31 GR GR20000401771T patent/GR3034079T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0682655B1 (de) | 2000-05-03 |
| WO1995015314A1 (de) | 1995-06-08 |
| ES2147601T3 (es) | 2000-09-16 |
| EP0682655A1 (de) | 1995-11-22 |
| DE59409324D1 (de) | 2000-06-08 |
| CA2155214C (en) | 2005-03-29 |
| US5686618A (en) | 1997-11-11 |
| JP3516454B2 (ja) | 2004-04-05 |
| CA2155214A1 (en) | 1995-06-08 |
| ATE192437T1 (de) | 2000-05-15 |
| JPH08506361A (ja) | 1996-07-09 |
| DE4442808A1 (de) | 1995-06-08 |
| DK0682655T3 (da) | 2000-08-07 |
| PT682655E (pt) | 2000-08-31 |
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