GR3025872T3 - Orally active derivatives of 1,3,5(10)-estratriene - Google Patents

Orally active derivatives of 1,3,5(10)-estratriene

Info

Publication number
GR3025872T3
GR3025872T3 GR980400045T GR980400045T GR3025872T3 GR 3025872 T3 GR3025872 T3 GR 3025872T3 GR 980400045 T GR980400045 T GR 980400045T GR 980400045 T GR980400045 T GR 980400045T GR 3025872 T3 GR3025872 T3 GR 3025872T3
Authority
GR
Greece
Prior art keywords
estratriene
orally active
active derivatives
beta
estratrienes
Prior art date
Application number
GR980400045T
Other languages
English (en)
Inventor
Hyun K Kim
Richard P Blye
Gabriel Bialy
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of GR3025872T3 publication Critical patent/GR3025872T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR980400045T 1993-09-17 1998-01-12 Orally active derivatives of 1,3,5(10)-estratriene GR3025872T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/122,853 US5554603A (en) 1993-09-17 1993-09-17 Orally active derivatives of 1,3,5(10)-estratriene
PCT/US1994/010393 WO1995007925A1 (en) 1993-09-17 1994-09-15 Orally active derivatives of 1,3,5(10)-estratriene

Publications (1)

Publication Number Publication Date
GR3025872T3 true GR3025872T3 (en) 1998-04-30

Family

ID=22405185

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400045T GR3025872T3 (en) 1993-09-17 1998-01-12 Orally active derivatives of 1,3,5(10)-estratriene

Country Status (11)

Country Link
US (1) US5554603A (el)
EP (1) EP0719276B1 (el)
JP (1) JP3993228B2 (el)
AT (1) ATE160573T1 (el)
AU (1) AU700576B2 (el)
CA (1) CA2171740C (el)
DE (1) DE69407057T2 (el)
DK (1) DK0719276T3 (el)
ES (1) ES2110258T3 (el)
GR (1) GR3025872T3 (el)
WO (1) WO1995007925A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548491B2 (en) * 1997-12-24 2003-04-15 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6503896B1 (en) 1997-12-24 2003-01-07 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6054446A (en) * 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
DE19906159A1 (de) * 1999-02-09 2000-08-10 Schering Ag 16-Hydroxyestratriene als selektiv wirksame Estrogene
AU2004237574A1 (en) * 2003-03-13 2004-11-18 Nitromed, Inc. Nitrosated and nitrosylated compounds, compositions and methods of use
WO2005116047A2 (en) * 2004-05-27 2005-12-08 Migenix Corp. 2-substituted 17-imino estrogen compounds for cytoprotection
WO2009111574A2 (en) * 2008-03-05 2009-09-11 Evestra, Inc. BISMETHYLENE-17α CARBOLACTONES AND RELATED USES
US20090269403A1 (en) * 2008-04-24 2009-10-29 Shaked Ze Ev Oral contraceptive dosage forms and methods of making such dosage forms
US8222237B2 (en) * 2008-11-25 2012-07-17 Evestra, Inc. Progestational 3-(6,6-ethylene-17B-hydroxy-3-oxo-17A-pregna-4-ene-17A-yl)propionic acid G-lactones
KR101828619B1 (ko) * 2010-03-28 2018-02-12 이브스트라, 인코포레이티드 질 내 약물 전달 장치

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1074493A (en) * 1963-06-12 1967-07-05 Roussel Uclaf Novel estrane derivatives and processes for preparing them
FR5241M (el) * 1966-02-24 1967-07-17
NL135316C (el) * 1966-11-18
US3980681A (en) * 1969-11-21 1976-09-14 Peter Job Sykes Process for the preparation of 11-β-nitro-oxysteroids
GB1332784A (en) * 1969-11-21 1973-10-03 Glaxo Lab Ltd Nitrates of steroid 11 beta-ols
US4705783A (en) * 1985-06-25 1987-11-10 Sri International 9α, 11β-substituted and 11β-substituted estranes

Also Published As

Publication number Publication date
DK0719276T3 (da) 1998-08-10
DE69407057T2 (de) 1998-04-09
EP0719276A1 (en) 1996-07-03
ATE160573T1 (de) 1997-12-15
ES2110258T3 (es) 1998-02-01
US5554603A (en) 1996-09-10
AU700576B2 (en) 1999-01-07
JP3993228B2 (ja) 2007-10-17
DE69407057D1 (de) 1998-01-08
EP0719276B1 (en) 1997-11-26
CA2171740C (en) 2005-07-26
CA2171740A1 (en) 1995-03-23
WO1995007925A1 (en) 1995-03-23
JPH09505802A (ja) 1997-06-10
AU7728494A (en) 1995-04-03

Similar Documents

Publication Publication Date Title
AU5278899A (en) 14,15-cyclopropanosteroids of the 19-norandrostane series, method for the production thereof and pharmaceutical preparations containing said compounds
IL87885A (en) Pharmaceutical compositions having antiprogestational and anti-estrogenic activities for the treatment of hormone- dependent tumors
GEP20033094B (en) Steroid Sulphatase Inhibitors
NL300017I1 (nl) Gesubstitueerde androsta-1,4-dieen-3,17-dionen, alsmede farmaceutische preparaten die dergelijke verbindingen bevatten.
MY114889A (en) 1-phenyl-3-dimethylamino-propane derivatives having pharmacological activity
CA2069483A1 (en) Steroid sulphatase inhibitors
HU9603584D0 (en) Sterol derivatives which applicable for regulation of meiosis
AU3020892A (en) Ethylenically unsaturated bile acid derivatives, processes for their preparation and precursors
WO1997004788A3 (en) Use of calendula glycosides for the treatment of psoriasis
GR3025872T3 (en) Orally active derivatives of 1,3,5(10)-estratriene
HRP930957A2 (en) Novel biologically active eburnamenine derivatives, maceutical compositions containing them and process for aring the same
EP0136569A3 (en) Isoflavone derivatives, their production and use
ZA934036B (en) Novel steroids with pregnane skeleton, pharmaceutical compositions containing them and process for preparing same.
GR3023311T3 (en) 17B-(3-Furyl) and 17B-(4-pyridazinyl)-5beta,14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same
MY110149A (en) Compounds for the treatment of neurodegenerative disorders
HUP9702480A3 (en) New polymorphous form of doxazosin-mesylate (form. i.), process for it's preparation and pharmaceutical compositions containing the same
ZA973289B (en) Steroids, their use as medicaments, their preparation process, the intermediates of this process and the compositions containing them.
AU6913087A (en) Treatment of menopausal symptoms
GR3031118T3 (en) Novel seco-D steroids active in the cardiovascular system and pharmaceutical compositions containing same
AU7101994A (en) Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose
HUP9702479A3 (en) New polymorphous form of doxazosin-mesylate (form ii.), process for it's preparation and pharmaceutical compositions containing the same
MY115795A (en) Substituted benzenesulfonylureas and -thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them
IL129627A0 (en) Novel CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
IL129625A0 (en) Novel (-)-enantionmers of CIS-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes
AU4513099A (en) Cycloalkyl-carboxylic acid esters of 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha.-methyltestosterone)