GR3018691T3 - Amino acids, peptides or derivatives thereof coupled to fats - Google Patents

Amino acids, peptides or derivatives thereof coupled to fats

Info

Publication number
GR3018691T3
GR3018691T3 GR960400092T GR960400092T GR3018691T3 GR 3018691 T3 GR3018691 T3 GR 3018691T3 GR 960400092 T GR960400092 T GR 960400092T GR 960400092 T GR960400092 T GR 960400092T GR 3018691 T3 GR3018691 T3 GR 3018691T3
Authority
GR
Greece
Prior art keywords
peptides
derivatives
amino acids
derivative
fats
Prior art date
Application number
GR960400092T
Other languages
English (en)
Inventor
Robert George Whittaker
Original Assignee
Commw Scient Ind Res Org
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commw Scient Ind Res Org filed Critical Commw Scient Ind Res Org
Publication of GR3018691T3 publication Critical patent/GR3018691T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fats And Perfumes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR960400092T 1989-12-22 1996-01-17 Amino acids, peptides or derivatives thereof coupled to fats GR3018691T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPJ803589 1989-12-22
PCT/AU1990/000599 WO1991009837A1 (en) 1989-12-22 1990-12-19 Amino acids, peptides or derivatives thereof coupled to fats

Publications (1)

Publication Number Publication Date
GR3018691T3 true GR3018691T3 (en) 1996-04-30

Family

ID=3774435

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960400092T GR3018691T3 (en) 1989-12-22 1996-01-17 Amino acids, peptides or derivatives thereof coupled to fats

Country Status (7)

Country Link
EP (1) EP0506748B1 (el)
AT (1) ATE131471T1 (el)
DE (1) DE69024230T2 (el)
DK (1) DK0506748T3 (el)
ES (1) ES2084150T3 (el)
GR (1) GR3018691T3 (el)
WO (1) WO1991009837A1 (el)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206027A (en) * 1990-09-13 1993-04-27 Fuji Photo Film Co., Ltd. Amphipathic compound and liposome comprising the same
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
CA2114125A1 (en) * 1991-07-26 1993-02-18 Wayne G. Reilly Self-adjuvanting peptide vaccine delivery system and production thereof
SE9302296D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab Amino acid supplement
US5792786A (en) 1993-08-02 1998-08-11 Commonwealth Scientific And Industrial Research Organisation Non-steroidal anti-inflammatory fatty acid conjugates and their therapeutic use thereof
HU224350B1 (hu) 1993-08-09 2005-08-29 Société de Conseils de Recherches et d'ApplicationScientifiques, S.A.S. Á Gyógyhatású peptidszármazékok
DE4437502A1 (de) * 1993-12-02 1995-06-08 Basf Ag Hirudin-Konjugate aus Hirudin und lipophilen Verbindungen
AUPM747694A0 (en) * 1994-08-16 1994-09-08 Commonwealth Scientific And Industrial Research Organisation Delivery of nucleic acids and peptides
US5952499A (en) * 1995-01-16 1999-09-14 Commonwealth Scientific And Industrial Research Organisation Therapeutic compound-fatty acid conjugates
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
AUPN741696A0 (en) * 1996-01-05 1996-01-25 Commonwealth Scientific And Industrial Research Organisation Delivery of nucleic acids ii
DE19605175A1 (de) 1996-02-13 1997-08-14 Sourovoi Andrej Dr Lipidverbindungen und deren Verwendung
US6239108B1 (en) 1996-07-11 2001-05-29 Biogen, Inc. Cell adhesion inhibitors
EP0914605B1 (en) 1996-07-25 2007-05-30 Biogen Idec MA Inc. Molecular model for vla-4 inhibitors
US6686350B1 (en) 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
AUPP051497A0 (en) * 1997-11-24 1997-12-18 University Of Melbourne, The Antimicrobial peptides
CZ298413B6 (cs) 1998-05-28 2007-09-26 Biogen Idec Ma Inc. Beta-Alaninový derivát, farmaceutická kompozice tento derivát obsahující a použití tohoto derivátu pro prípravu léciva
EP1741428A3 (en) 1999-08-13 2007-05-09 Biogen Idec MA, Inc. Cell adhesion inhibitors
US6875743B1 (en) 2000-11-28 2005-04-05 Biogen, Inc. Cell adhesion inhibitors
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CA2550581C (en) 2003-12-19 2013-04-16 The University Of Melbourne Antimicrobial composition comprising a peptide derived from k-casein and a divalent cation
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004398A1 (en) * 1984-04-03 1985-10-10 Takeda Chemical Industries, Ltd. Lipid derivatives
WO1986004894A1 (en) * 1985-02-15 1986-08-28 Takeda Chemical Industries, Ltd. Lipid derivatives
US4751219A (en) * 1985-02-05 1988-06-14 Nederlandse Centrale Organisatie Voor Toegepast-Natuur-Wetenschappelijk Onderzoek Synthetic glycolipides, a process for the preparation thereof and several uses for these synthetic glycolipides
DE3627924A1 (de) 1986-08-18 1988-03-03 Henkel Kgaa Verwendung von aminofettsaeureamiden als vernetzungsmittel
DE3801587A1 (de) * 1988-01-21 1989-08-03 Hoechst Ag Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
WO1989007109A1 (en) * 1988-02-01 1989-08-10 The Upjohn Company Renin inhibiting peptides with polar end groups
GB2217319A (en) * 1988-04-19 1989-10-25 Synpharm Ltd Racemic and optically active fatty amino acids, their homo- abd hetero-oligomers and conjugates, the process of their production, their pharmaceutical composi

Also Published As

Publication number Publication date
EP0506748A4 (en) 1992-12-02
AU649242B2 (en) 1994-05-19
EP0506748A1 (en) 1992-10-07
DE69024230D1 (de) 1996-01-25
DE69024230T2 (de) 1996-05-02
WO1991009837A1 (en) 1991-07-11
ES2084150T3 (es) 1996-05-01
DK0506748T3 (da) 1996-01-22
EP0506748B1 (en) 1995-12-13
AU7033691A (en) 1991-07-24
ATE131471T1 (de) 1995-12-15

Similar Documents

Publication Publication Date Title
GR3018691T3 (en) Amino acids, peptides or derivatives thereof coupled to fats
BR9107206A (pt) Processo para produzir uma variante de proteina que evoca uma resposta imunogenica diminuida em animais,produtos obtidos,composicao e uso
MX9403570A (es) Conjugados de farmaco-ligando, proceso para su preparacion y composicionesfarmaceuticas que los incluyen.
SG47430A1 (en) Pharmaceutical and other dosage forms
BG103335A (en) Application of fumaric acid derivatives
HK1021741A1 (en) Modulators of beta-amyloid peptide aggregation comprising d-amino acids
SE9100799D0 (sv) Recombinant human factor viii derivatives
WO2000012542A3 (en) Cytotoxic lactoferrin derivatives modified by bulky or lipophilic moieties
MX9703642A (es) Metodos para el tratamiento de esclerosis multiple utilizando analogos de peptido en la posicion 91 de la proteina basica de mielina humana.
GB9019919D0 (en) Purification of proteins
DK0953576T3 (da) Aktivt hedgehog-proteinkonjugat, fremgangsmåde til fremstilling heraf og anvendelse
NO971621L (no) Keratinocyttvekstfaktoranaloger
ES2196187T3 (es) Conjugados peptidicos derivados de las hormonas timicas, su utilizacion a titulo de medicamento y composiciones que los contienen.
DE3568048D1 (en) Process for the synthesis of peptides
BG97123A (bg) Производни на човешка, стимулирана от жлъчните соли, липаза и фармацевтични състави на тяхна основа
FI883589A0 (fi) Menetelmä tyydyttämättömien aminohappoyhdisteiden valmistamiseksi
DE3370026D1 (en) Biologically active conjugates and their preparation and use
DE69005451D1 (de) Somatotropinanaloge.
ES2084348T3 (es) N-((4,5-dihidroxi- y 4,5,8-trihidroxi-9,10-dihidro-9,10-dioxo-2-antracen-il)carbonil)aminoacidos utiles en la terapia de afecciones osteoarticulares.
JPS643161A (en) (2-cyano-2-oxyiminoacetyl)-amino acid derivative
ATE86260T1 (de) Peptid-molekuele, wirksam gegen gram-positive keime.
NZ511747A (en) Regulatory/unfolding peptides of ezrin
GB8806571D0 (en) Supports for proteins & amino acids
AU542310B2 (en) Glicentin related purified peptide having 30 amino acids
KR910004663A (ko) 정신-약리학적 펩티드