DE69024230T2 - An fette gebundene aminosäuren, peptide oder deren derivate - Google Patents
An fette gebundene aminosäuren, peptide oder deren derivateInfo
- Publication number
- DE69024230T2 DE69024230T2 DE69024230T DE69024230T DE69024230T2 DE 69024230 T2 DE69024230 T2 DE 69024230T2 DE 69024230 T DE69024230 T DE 69024230T DE 69024230 T DE69024230 T DE 69024230T DE 69024230 T2 DE69024230 T2 DE 69024230T2
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- amino acids
- derivative
- fats
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fats And Perfumes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPJ803589 | 1989-12-22 | ||
PCT/AU1990/000599 WO1991009837A1 (en) | 1989-12-22 | 1990-12-19 | Amino acids, peptides or derivatives thereof coupled to fats |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69024230D1 DE69024230D1 (de) | 1996-01-25 |
DE69024230T2 true DE69024230T2 (de) | 1996-05-02 |
Family
ID=3774435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69024230T Expired - Fee Related DE69024230T2 (de) | 1989-12-22 | 1990-12-19 | An fette gebundene aminosäuren, peptide oder deren derivate |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0506748B1 (de) |
AT (1) | ATE131471T1 (de) |
DE (1) | DE69024230T2 (de) |
DK (1) | DK0506748T3 (de) |
ES (1) | ES2084150T3 (de) |
GR (1) | GR3018691T3 (de) |
WO (1) | WO1991009837A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5206027A (en) * | 1990-09-13 | 1993-04-27 | Fuji Photo Film Co., Ltd. | Amphipathic compound and liposome comprising the same |
US5554728A (en) * | 1991-07-23 | 1996-09-10 | Nexstar Pharmaceuticals, Inc. | Lipid conjugates of therapeutic peptides and protease inhibitors |
CA2114125A1 (en) * | 1991-07-26 | 1993-02-18 | Wayne G. Reilly | Self-adjuvanting peptide vaccine delivery system and production thereof |
SE9302296D0 (sv) * | 1993-07-02 | 1993-07-02 | Kabi Pharmacia Ab | Amino acid supplement |
US5792786A (en) * | 1993-08-02 | 1998-08-11 | Commonwealth Scientific And Industrial Research Organisation | Non-steroidal anti-inflammatory fatty acid conjugates and their therapeutic use thereof |
ES2229045T3 (es) * | 1993-08-09 | 2005-04-16 | Sod Conseils Rech Applic | Derivados de peptidos terapeuticos. |
DE4437502A1 (de) * | 1993-12-02 | 1995-06-08 | Basf Ag | Hirudin-Konjugate aus Hirudin und lipophilen Verbindungen |
AUPM747694A0 (en) * | 1994-08-16 | 1994-09-08 | Commonwealth Scientific And Industrial Research Organisation | Delivery of nucleic acids and peptides |
US5952499A (en) * | 1995-01-16 | 1999-09-14 | Commonwealth Scientific And Industrial Research Organisation | Therapeutic compound-fatty acid conjugates |
US6248713B1 (en) | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
AUPN741696A0 (en) * | 1996-01-05 | 1996-01-25 | Commonwealth Scientific And Industrial Research Organisation | Delivery of nucleic acids ii |
DE19605175A1 (de) * | 1996-02-13 | 1997-08-14 | Sourovoi Andrej Dr | Lipidverbindungen und deren Verwendung |
US6239108B1 (en) | 1996-07-11 | 2001-05-29 | Biogen, Inc. | Cell adhesion inhibitors |
US6686350B1 (en) | 1996-07-25 | 2004-02-03 | Biogen, Inc. | Cell adhesion inhibitors |
DK0914605T3 (da) | 1996-07-25 | 2007-09-10 | Biogen Idec Inc | Molekylemodel for VLA-4-inhibitorer |
AUPP051497A0 (en) * | 1997-11-24 | 1997-12-18 | University Of Melbourne, The | Antimicrobial peptides |
PL198189B1 (pl) | 1998-05-28 | 2008-06-30 | Biogen Idec Ma | (R)-N-{[4-{[(2-metylofenyloamino)-karbonylo]amino}fenylo]acetylo}-L-prolilo-3-metylo]-ß-alanina, jej zastosowanie i kompozycja farmaceutyczna ją zawierająca |
JP2003506491A (ja) | 1999-08-13 | 2003-02-18 | バイオジェン インコーポレイテッド | 細胞接着インヒビター |
US6875743B1 (en) | 2000-11-28 | 2005-04-05 | Biogen, Inc. | Cell adhesion inhibitors |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US8106152B2 (en) | 2003-12-19 | 2012-01-31 | Dairy Australia Limited | Antimicrobial composition |
US7196112B2 (en) | 2004-07-16 | 2007-03-27 | Biogen Idec Ma Inc. | Cell adhesion inhibitors |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986004894A1 (en) * | 1985-02-15 | 1986-08-28 | Takeda Chemical Industries, Ltd. | Lipid derivatives |
WO1985004398A1 (en) * | 1984-04-03 | 1985-10-10 | Takeda Chemical Industries, Ltd. | Lipid derivatives |
US4751219A (en) * | 1985-02-05 | 1988-06-14 | Nederlandse Centrale Organisatie Voor Toegepast-Natuur-Wetenschappelijk Onderzoek | Synthetic glycolipides, a process for the preparation thereof and several uses for these synthetic glycolipides |
DE3627924A1 (de) | 1986-08-18 | 1988-03-03 | Henkel Kgaa | Verwendung von aminofettsaeureamiden als vernetzungsmittel |
DE3801587A1 (de) * | 1988-01-21 | 1989-08-03 | Hoechst Ag | Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung |
EP0397779A1 (de) | 1988-02-01 | 1990-11-22 | The Upjohn Company | Renin inhibierende peptide mit polaren endgruppen |
GB2217319A (en) * | 1988-04-19 | 1989-10-25 | Synpharm Ltd | Racemic and optically active fatty amino acids, their homo- abd hetero-oligomers and conjugates, the process of their production, their pharmaceutical composi |
-
1990
- 1990-12-19 WO PCT/AU1990/000599 patent/WO1991009837A1/en active IP Right Grant
- 1990-12-19 AT AT91901249T patent/ATE131471T1/de not_active IP Right Cessation
- 1990-12-19 ES ES91901249T patent/ES2084150T3/es not_active Expired - Lifetime
- 1990-12-19 DK DK91901249.2T patent/DK0506748T3/da active
- 1990-12-19 EP EP91901249A patent/EP0506748B1/de not_active Expired - Lifetime
- 1990-12-19 DE DE69024230T patent/DE69024230T2/de not_active Expired - Fee Related
-
1996
- 1996-01-17 GR GR960400092T patent/GR3018691T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3018691T3 (en) | 1996-04-30 |
EP0506748A4 (en) | 1992-12-02 |
ES2084150T3 (es) | 1996-05-01 |
AU7033691A (en) | 1991-07-24 |
DE69024230D1 (de) | 1996-01-25 |
EP0506748B1 (de) | 1995-12-13 |
DK0506748T3 (da) | 1996-01-22 |
WO1991009837A1 (en) | 1991-07-11 |
AU649242B2 (en) | 1994-05-19 |
ATE131471T1 (de) | 1995-12-15 |
EP0506748A1 (de) | 1992-10-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |