GR20120100185A - Μεθοδος διερευνησης της παρουσιας ενδοκυτταριων μολυσματικων παραγοντων σε κυτταρα του σπερματος - Google Patents

Μεθοδος διερευνησης της παρουσιας ενδοκυτταριων μολυσματικων παραγοντων σε κυτταρα του σπερματος

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Publication number
GR20120100185A
GR20120100185A GR20120100185A GR20120100185A GR20120100185A GR 20120100185 A GR20120100185 A GR 20120100185A GR 20120100185 A GR20120100185 A GR 20120100185A GR 20120100185 A GR20120100185 A GR 20120100185A GR 20120100185 A GR20120100185 A GR 20120100185A
Authority
GR
Greece
Prior art keywords
exploration
infectious agents
endocellular
sperm cells
spermatozoids
Prior art date
Application number
GR20120100185A
Other languages
English (en)
Other versions
GR1008033B (el
Inventor
Βασιλειος Τσιλιβακος
Αγγελος Γκριτζαπης
Original Assignee
Βασιλειος Τσιλιβακος
Αγγελος Γκριτζαπης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Βασιλειος Τσιλιβακος, Αγγελος Γκριτζαπης filed Critical Βασιλειος Τσιλιβακος
Priority to GR20120100185A priority Critical patent/GR1008033B/el
Priority to CN201380023706.3A priority patent/CN104303059B/zh
Priority to PCT/GR2013/000016 priority patent/WO2013144662A1/en
Priority to AU2013239416A priority patent/AU2013239416A1/en
Priority to SG10201704802YA priority patent/SG10201704802YA/en
Priority to CA2868707A priority patent/CA2868707A1/en
Priority to US14/387,794 priority patent/US20150064691A1/en
Priority to KR20147029210A priority patent/KR20150042146A/ko
Priority to SG11201406096QA priority patent/SG11201406096QA/en
Priority to IN8201DEN2014 priority patent/IN2014DN08201A/en
Priority to EP13721796.4A priority patent/EP2831588A1/en
Priority to JP2015502463A priority patent/JP6301310B2/ja
Priority to MX2014011593A priority patent/MX2014011593A/es
Priority to RU2014141207A priority patent/RU2664734C2/ru
Publication of GR20120100185A publication Critical patent/GR20120100185A/el
Publication of GR1008033B publication Critical patent/GR1008033B/el
Priority to CL2014002584A priority patent/CL2014002584A1/es
Priority to IL234844A priority patent/IL234844A0/en
Priority to ZA2014/07818A priority patent/ZA201407818B/en
Priority to HK15101974.1A priority patent/HK1201579A1/xx
Priority to AU2018274968A priority patent/AU2018274968A1/en
Priority to AU2018275005A priority patent/AU2018275005A1/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56994—Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Η παρούσα εφεύρεση περιγράφει μέθοδο διερεύνησης παρουσίας χλαμυδίων, ιών και λοιπών μολυσματικών παραγόντων σε σπερματοζωάρια, με εξετάσεις που εφαρμόζονται με τη χρήση τεχνικής ανοσοφθορισμού σε συνδυασμό με κυτταρομετρία ροής. Η διερεύνηση αυτή γίνεται ενδοκυτταρικά, για μικροοργανισμούς ευρισκόμενους εντός των σπερματοζωαρίων με τη χρήση κατεργασίας χαλάρωσης του DNA, άλλως επίσης και για μικροοργανισμούς προσκολλημένους στην επιφάνεια των σπερματοζωαρίων.
GR20120100185A 2012-03-29 2012-03-29 Μεθοδος διερευνησης της παρουσιας ενδοκυτταριων μολυσματικων παραγοντων σε κυτταρα του σπερματος GR1008033B (el)

Priority Applications (20)

Application Number Priority Date Filing Date Title
GR20120100185A GR1008033B (el) 2012-03-29 2012-03-29 Μεθοδος διερευνησης της παρουσιας ενδοκυτταριων μολυσματικων παραγοντων σε κυτταρα του σπερματος
IN8201DEN2014 IN2014DN08201A (el) 2012-03-29 2013-03-29
MX2014011593A MX2014011593A (es) 2012-03-29 2013-03-29 Metodos de deteccion intracelular de agente infeccioso en celulas espermaticas.
AU2013239416A AU2013239416A1 (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
SG10201704802YA SG10201704802YA (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
CA2868707A CA2868707A1 (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
US14/387,794 US20150064691A1 (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
KR20147029210A KR20150042146A (ko) 2012-03-29 2013-03-29 정자 세포에서 세포내 감염제의 검출 방법
SG11201406096QA SG11201406096QA (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
CN201380023706.3A CN104303059B (zh) 2012-03-29 2013-03-29 检测精细胞中细胞内感染原的方法
EP13721796.4A EP2831588A1 (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
JP2015502463A JP6301310B2 (ja) 2012-03-29 2013-03-29 精細胞中の細胞内感染因子の検出方法
PCT/GR2013/000016 WO2013144662A1 (en) 2012-03-29 2013-03-29 Method of intracellular infectious agent detection in sperm cells
RU2014141207A RU2664734C2 (ru) 2012-03-29 2013-03-29 Способ обнаружения внутриклеточных возбудителей инфекции в клетках спермы
CL2014002584A CL2014002584A1 (es) 2012-03-29 2014-09-26 Método de detección de agentes infecciosos intracelulares en células espermáticas, que comprende inmunoflurescencia; y kit para llevar a cabo el método.
IL234844A IL234844A0 (en) 2012-03-29 2014-09-28 A method for identifying the cause of intercellular contamination in sperm cells
ZA2014/07818A ZA201407818B (en) 2012-03-29 2014-10-27 Method of intracellular infectious agent detection in sperm cells
HK15101974.1A HK1201579A1 (en) 2012-03-29 2015-02-27 Method of intracellular infectious agent detection in sperm cells
AU2018274968A AU2018274968A1 (en) 2012-03-29 2018-12-06 Method of intracellular infectious agent detection in sperm cells
AU2018275005A AU2018275005A1 (en) 2012-03-29 2018-12-07 Method of intracellular infectious agent detection in sperm cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20120100185A GR1008033B (el) 2012-03-29 2012-03-29 Μεθοδος διερευνησης της παρουσιας ενδοκυτταριων μολυσματικων παραγοντων σε κυτταρα του σπερματος

Publications (2)

Publication Number Publication Date
GR20120100185A true GR20120100185A (el) 2013-10-15
GR1008033B GR1008033B (el) 2013-11-18

Family

ID=48407746

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20120100185A GR1008033B (el) 2012-03-29 2012-03-29 Μεθοδος διερευνησης της παρουσιας ενδοκυτταριων μολυσματικων παραγοντων σε κυτταρα του σπερματος

Country Status (16)

Country Link
US (1) US20150064691A1 (el)
EP (1) EP2831588A1 (el)
JP (1) JP6301310B2 (el)
KR (1) KR20150042146A (el)
CN (1) CN104303059B (el)
AU (3) AU2013239416A1 (el)
CA (1) CA2868707A1 (el)
CL (1) CL2014002584A1 (el)
GR (1) GR1008033B (el)
HK (1) HK1201579A1 (el)
IL (1) IL234844A0 (el)
IN (1) IN2014DN08201A (el)
RU (1) RU2664734C2 (el)
SG (2) SG11201406096QA (el)
WO (1) WO2013144662A1 (el)
ZA (1) ZA201407818B (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10161850B2 (en) * 2015-03-23 2018-12-25 Intellicyt Corporation Evaluating biological material for unassociated virus-size particles with influenza virus epitope
CN105527430A (zh) * 2016-01-21 2016-04-27 广州锐达生物科技有限公司 一种直接检测肠道病毒71型和柯萨奇病毒a16型的试剂盒及其应用
CN111474339A (zh) * 2020-04-17 2020-07-31 浙江康佰裕生物科技有限公司 一种利用荧光标记痘病毒颗粒的方法及其应用
RU2738798C1 (ru) * 2020-08-31 2020-12-16 Василий Васильевич Ашапкин Способ количественного определения вирусного инфицирования сперматозоидов
CN115032391A (zh) * 2022-06-21 2022-09-09 成都思瑞多医疗科技有限公司 精子唾液酸酶1/3检测试剂盒及其制备方法、检测精子唾液酸酶1/3表达水平的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2306183A1 (en) * 1997-10-29 1999-05-06 Genentech, Inc. Wnt-1 induced secreted polypeptides: wisp-1, -2 and -3
GB0016920D0 (en) * 2000-07-10 2000-08-30 Univ Cambridge Tech Decondensation of DNA
GB0130947D0 (en) * 2001-12-24 2002-02-13 Lee Helen Improved sample preparation for the detection of infectious agents
JP4718459B2 (ja) * 2003-07-25 2011-07-06 メルク セローノ ソシエテ アノニム 雄性の精子染色体異常の減少のための卵胞刺激ホルモンの使用
WO2005116234A2 (en) * 2004-04-16 2005-12-08 University Of Massachusetts Detection and quantification of intracellular pathogens

Also Published As

Publication number Publication date
GR1008033B (el) 2013-11-18
IN2014DN08201A (el) 2015-05-01
US20150064691A1 (en) 2015-03-05
CN104303059B (zh) 2016-08-17
IL234844A0 (en) 2014-12-31
RU2014141207A (ru) 2016-05-27
SG10201704802YA (en) 2017-07-28
SG11201406096QA (en) 2014-10-30
HK1201579A1 (en) 2015-09-04
EP2831588A1 (en) 2015-02-04
RU2664734C2 (ru) 2018-08-22
WO2013144662A1 (en) 2013-10-03
AU2013239416A1 (en) 2014-10-16
CA2868707A1 (en) 2013-10-03
KR20150042146A (ko) 2015-04-20
ZA201407818B (en) 2016-05-25
CN104303059A (zh) 2015-01-21
AU2018275005A1 (en) 2019-01-03
JP6301310B2 (ja) 2018-03-28
CL2014002584A1 (es) 2015-06-19
JP2015513103A (ja) 2015-04-30
AU2018274968A1 (en) 2019-01-03

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Effective date: 20140102