GR1007725B - Μεθοδος δια την παρασκευη υδροχλωρικης ντουλοξετινης υψηλης καθαροτητας - Google Patents
Μεθοδος δια την παρασκευη υδροχλωρικης ντουλοξετινης υψηλης καθαροτηταςInfo
- Publication number
- GR1007725B GR1007725B GR20110100599A GR20110100599A GR1007725B GR 1007725 B GR1007725 B GR 1007725B GR 20110100599 A GR20110100599 A GR 20110100599A GR 20110100599 A GR20110100599 A GR 20110100599A GR 1007725 B GR1007725 B GR 1007725B
- Authority
- GR
- Greece
- Prior art keywords
- preparation
- highly pure
- duloxetine hydrochloride
- pure duloxetine
- duloxetine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Η παρούσα εφεύρεση αφορά βελτιωμένη μέθοδο παρασκευής Ντουλοξετίνης και φαρμακευτικά αποδεκτών αλάτων ή παραγώγων αυτής και συγκεκριμένα μια μέθοδο για μαζική παραγωγή υδροχλωρικής Ντουλοξετίνης με υψηλή απόδοση και υψηλή εναντιομερική και χημική καθαρότητα.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20110100599A GR1007725B (el) | 2011-10-17 | 2011-10-17 | Μεθοδος δια την παρασκευη υδροχλωρικης ντουλοξετινης υψηλης καθαροτητας |
IN1022KON2014 IN2014KN01022A (el) | 2011-10-17 | 2012-10-16 | |
CN201280051251.1A CN103958494A (zh) | 2011-10-17 | 2012-10-16 | 高纯度盐酸度洛西汀的制备方法 |
PCT/EP2012/004312 WO2013056809A1 (en) | 2011-10-17 | 2012-10-16 | Process for the preparation of highly pure duloxetine hydrochloride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR20110100599A GR1007725B (el) | 2011-10-17 | 2011-10-17 | Μεθοδος δια την παρασκευη υδροχλωρικης ντουλοξετινης υψηλης καθαροτητας |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1007725B true GR1007725B (el) | 2012-10-18 |
Family
ID=47071219
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20110100599A GR1007725B (el) | 2011-10-17 | 2011-10-17 | Μεθοδος δια την παρασκευη υδροχλωρικης ντουλοξετινης υψηλης καθαροτητας |
Country Status (4)
Country | Link |
---|---|
CN (1) | CN103958494A (el) |
GR (1) | GR1007725B (el) |
IN (1) | IN2014KN01022A (el) |
WO (1) | WO2013056809A1 (el) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2060559A1 (en) * | 2007-11-19 | 2009-05-20 | Cadila Pharmaceuticals Limited | Process for the preparation of enantiomerically pure 3-hydroxy-3-arylpropylamines and their optical stereoisomers |
WO2010003942A2 (en) * | 2008-07-07 | 2010-01-14 | Krka, D.D. Novo Mesto | Preparation of duloxetine and its pharmaceutically acceptable salts by the use of asymmetric transfer hydrogenation process |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR880007433A (ko) | 1986-12-22 | 1988-08-27 | 메리 앤 터커 | 3-아릴옥시-3-치환된 프로판아민 |
US7538232B2 (en) * | 2006-01-19 | 2009-05-26 | Eli Lilly And Company | Process for the asymmetric synthesis of duloxetine |
WO2009074883A2 (en) | 2007-11-06 | 2009-06-18 | Medichem, S.A. | Improved process for preparing duloxetine |
-
2011
- 2011-10-17 GR GR20110100599A patent/GR1007725B/el active IP Right Grant
-
2012
- 2012-10-16 IN IN1022KON2014 patent/IN2014KN01022A/en unknown
- 2012-10-16 WO PCT/EP2012/004312 patent/WO2013056809A1/en active Application Filing
- 2012-10-16 CN CN201280051251.1A patent/CN103958494A/zh active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2060559A1 (en) * | 2007-11-19 | 2009-05-20 | Cadila Pharmaceuticals Limited | Process for the preparation of enantiomerically pure 3-hydroxy-3-arylpropylamines and their optical stereoisomers |
WO2010003942A2 (en) * | 2008-07-07 | 2010-01-14 | Krka, D.D. Novo Mesto | Preparation of duloxetine and its pharmaceutically acceptable salts by the use of asymmetric transfer hydrogenation process |
Also Published As
Publication number | Publication date |
---|---|
IN2014KN01022A (el) | 2015-10-09 |
CN103958494A (zh) | 2014-07-30 |
WO2013056809A1 (en) | 2013-04-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PG | Patent granted |
Effective date: 20121122 |