GR1004660B - Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους - Google Patents

Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους

Info

Publication number
GR1004660B
GR1004660B GR20030100275A GR2003100275A GR1004660B GR 1004660 B GR1004660 B GR 1004660B GR 20030100275 A GR20030100275 A GR 20030100275A GR 2003100275 A GR2003100275 A GR 2003100275A GR 1004660 B GR1004660 B GR 1004660B
Authority
GR
Greece
Prior art keywords
advanced
pharmaceutical compositions
alendronate sodium
preparation methods
sodium trihydrate
Prior art date
Application number
GR20030100275A
Other languages
English (en)
Inventor
Original Assignee
������������, �������� ��� ����������� �������� �������� ��� �.�. ��������-������������ �.�.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������������, �������� ��� ����������� �������� �������� ��� �.�. ��������-������������ �.�. filed Critical ������������, �������� ��� ����������� �������� �������� ��� �.�. ��������-������������ �.�.
Priority to GR20030100275A priority Critical patent/GR1004660B/el
Priority to DE602004016419T priority patent/DE602004016419D1/de
Priority to AT04386021T priority patent/ATE407680T1/de
Priority to EP04386021A priority patent/EP1491199B1/en
Priority to PT04386021T priority patent/PT1491199E/pt
Priority to ES04386021T priority patent/ES2314358T3/es
Publication of GR1004660B publication Critical patent/GR1004660B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

παρούσα εφεύρεση βρίσκει εφαρμογή στην τυποποίηση δισκίων, που περιλαμβάνουν μια θεραπευτικώς δραστική ποσότητα τριϋδρικού αλλεννδρονικού νατρίου (τριϋδρικού μετά νατρίου άλατος του 4-άμινο-1-υδροξυβουτυλιδενο-1,1-διφωσφονικού οξέος) ως δραστικό συστατκό και spray dried μαλτόζη ή μαννιτόλη σε συνδυασμό με crospovidone και στεατικό ασβέστιο, καθώς και μία μέθοδο για την παρασκευήτους με διαδικασία ξηρής κοκκοποίησης. ΰ
GR20030100275A 2003-06-25 2003-06-25 Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους GR1004660B (el)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GR20030100275A GR1004660B (el) 2003-06-25 2003-06-25 Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους
DE602004016419T DE602004016419D1 (de) 2003-06-25 2004-06-17 Pharmazeutische Zubereitung von Alendronat Natrium Trihydrat und Verfahren deren Herstellung
AT04386021T ATE407680T1 (de) 2003-06-25 2004-06-17 Pharmazeutische zubereitung von alendronat natrium trihydrat und verfahren deren herstellung
EP04386021A EP1491199B1 (en) 2003-06-25 2004-06-17 Pharmaceutical compositions of alendronate sodium trihydrate and process for the preparation thereof
PT04386021T PT1491199E (pt) 2003-06-25 2004-06-17 Composições farmacêuticas de alendronato de sódio tri-hidratado e processo para a sua preparação
ES04386021T ES2314358T3 (es) 2003-06-25 2004-06-17 Composiciones farmaceuticas de alendronato sodico trihidratado y procedimiento para la preparacion de las mismas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20030100275A GR1004660B (el) 2003-06-25 2003-06-25 Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους

Publications (1)

Publication Number Publication Date
GR1004660B true GR1004660B (el) 2004-08-25

Family

ID=33187103

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20030100275A GR1004660B (el) 2003-06-25 2003-06-25 Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους

Country Status (6)

Country Link
EP (1) EP1491199B1 (el)
AT (1) ATE407680T1 (el)
DE (1) DE602004016419D1 (el)
ES (1) ES2314358T3 (el)
GR (1) GR1004660B (el)
PT (1) PT1491199E (el)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006046100A1 (en) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Pharmaceutical composition of alendronic acid

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0616794D0 (en) 2006-08-24 2006-10-04 Arrow Int Ltd Solid dosage form

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2254060C (en) * 1996-05-17 2007-05-01 Merck & Co., Inc. Effervescent bisphosphonate formulation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006046100A1 (en) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Pharmaceutical composition of alendronic acid

Also Published As

Publication number Publication date
EP1491199A1 (en) 2004-12-29
ES2314358T3 (es) 2009-03-16
DE602004016419D1 (de) 2008-10-23
PT1491199E (pt) 2008-12-12
EP1491199B1 (en) 2008-09-10
ATE407680T1 (de) 2008-09-15

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Effective date: 20170109