GR1000263B - Μεθοδος παρασκευης αλατος της πενταμιδινης. - Google Patents
Μεθοδος παρασκευης αλατος της πενταμιδινης.Info
- Publication number
- GR1000263B GR1000263B GR880100751A GR880100751A GR1000263B GR 1000263 B GR1000263 B GR 1000263B GR 880100751 A GR880100751 A GR 880100751A GR 880100751 A GR880100751 A GR 880100751A GR 1000263 B GR1000263 B GR 1000263B
- Authority
- GR
- Greece
- Prior art keywords
- pentamidine
- salts
- aids
- preparating
- pentamidine salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/255—Tartaric acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/08—Acetic acid
- C07C53/10—Salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/08—Lactic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/10—Polyhydroxy carboxylic acids
- C07C59/105—Polyhydroxy carboxylic acids having five or more carbon atoms, e.g. aldonic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/265—Citric acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
'Αλατα της πενταμιδίνης, διαμορφώσεις που περιέχουν τέτοια άλατα και η χρήση τέτοιων αλάτων για την θεραπευτική ή προφυλακτική αγωγή του PNEUMOCYSTIS CARINII. Η γλυκονική και γαλακτική πενταμιδίνη ανεκαλύφθησαν και ευρέθησαν ότι έχουν μεγάλη διαλυτότητα εις ύδωρ ενώ παρέχουν δυναμικώς ολιγώτερο τοξικές εναλλακτικές λύσεις της ισεθειονικής πενταμιδίνης, ιδίως για χορήγηση υπό μορφή αερολύματος σε ασθενείς πάσχοντες από σύνδρομο επίκτητης ανοσολογικής ανεπάρκειας, AIDS ή σύνδρομο σχετιζόμενο με το AIDS, ARC. ω
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11828487A | 1987-11-06 | 1987-11-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GR1000263B true GR1000263B (el) | 1992-05-12 |
Family
ID=22377637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR880100751A GR1000263B (el) | 1987-11-06 | 1988-11-04 | Μεθοδος παρασκευης αλατος της πενταμιδινης. |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0315467A3 (el) |
JP (1) | JPH02150A (el) |
KR (1) | KR970008156B1 (el) |
CN (1) | CN1020897C (el) |
AU (1) | AU618762B2 (el) |
BR (1) | BR8805759A (el) |
CA (1) | CA1336003C (el) |
DK (1) | DK616088A (el) |
FI (1) | FI885020A (el) |
GR (1) | GR1000263B (el) |
IL (1) | IL88159A (el) |
IN (1) | IN168530B (el) |
MX (1) | MX13665A (el) |
NO (1) | NO171723C (el) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995013796A1 (en) * | 1993-11-16 | 1995-05-26 | Depotech Corporation | Vesicles with controlled release of actives |
JP2770970B2 (ja) * | 1987-04-09 | 1998-07-02 | フアイソンズ・ピーエルシー | ペンタミジンを含有する医薬組成物 |
US5366726A (en) * | 1987-12-23 | 1994-11-22 | The Regents Of The University Of California | Suppression of Pneumocystis carinii using aerosolized pentamidine treatment |
US5364615A (en) * | 1987-12-23 | 1994-11-15 | Regents Of The University Of California | Prophylaxis of pneumocystis carinii with aerosilized pentamidine |
US5807572A (en) * | 1988-02-18 | 1998-09-15 | Depotech Corporation | Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride |
EP0543770B1 (en) * | 1988-03-31 | 1997-08-13 | ORBISPHERE LABORATORIES (INC.), Wilmington, Succursale de Collonge-Bellerive | Ozone detection |
GB8903438D0 (en) * | 1989-02-15 | 1989-04-05 | May & Baker Ltd | New compositions of matter |
DE4108903A1 (de) * | 1990-08-06 | 1992-02-13 | Nattermann A & Cie | Pharmazeutisches produkt |
US5556637A (en) * | 1990-08-06 | 1996-09-17 | A. Nattermann & Cie. Gmbh | Water containing liposome system |
DE4122744C2 (de) * | 1990-08-06 | 1994-02-03 | Nattermann A & Cie | Wäßriges Liposomensystem und Verfahren zu seiner Herstellung |
DE4122661C2 (de) * | 1990-08-06 | 1996-07-11 | Nattermann A & Cie | Pharmazeutisches Produkt zur Behandlung von Pneumocystis-carinii-Pneumonie |
US6663885B1 (en) | 1993-03-15 | 2003-12-16 | A. Natterman & Cie Gmbh | Aqueous liposome system and a method for the preparation of such a liposome system |
JP4459303B2 (ja) * | 1995-09-19 | 2010-04-28 | セルラー サイエンセズ インコーポレイテッド | 炎症反応に起因する哺乳類の疾病の治療方法およびその組成物 |
KR100219601B1 (ko) * | 1996-05-15 | 1999-09-01 | 윤종용 | 인쇄면 판별영역을 갖는 ohp 및 승화형 열전사 프린터의 ohp 인쇄면 판별 방법 및 이에 적합한 장치 |
DE10149919A1 (de) * | 2001-10-10 | 2003-04-24 | Biosphings Ag | Neue Salze von Guanidinderivaten und pharmazeutische Zubereitungen daraus |
JP3972876B2 (ja) * | 2003-09-03 | 2007-09-05 | 日産自動車株式会社 | エンジンの燃料カット制御装置 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB575145A (en) * | 1944-02-23 | 1946-02-05 | May & Baker Ltd | Improvements in or relating to the preparation of amidine salts |
US2410796A (en) * | 1942-04-11 | 1946-11-05 | May & Baker Ltd | Soluble amidine salts |
US2425221A (en) * | 1942-07-27 | 1947-08-05 | May & Baker Ltd | Production of amidine salts |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU620025B2 (en) * | 1987-03-26 | 1992-02-13 | Sloan-Kettering Institute For Cancer Research | Method of preventing pneumocystis carinii pneumonia using pentamidine in an aerosol form |
-
1988
- 1988-10-24 IN IN876/CAL/88A patent/IN168530B/en unknown
- 1988-10-25 IL IL8815988A patent/IL88159A/en not_active IP Right Cessation
- 1988-10-28 AU AU24476/88A patent/AU618762B2/en not_active Ceased
- 1988-10-31 JP JP63277195A patent/JPH02150A/ja active Pending
- 1988-11-01 FI FI885020A patent/FI885020A/fi not_active Application Discontinuation
- 1988-11-02 NO NO884881A patent/NO171723C/no unknown
- 1988-11-04 BR BR888805759A patent/BR8805759A/pt not_active Application Discontinuation
- 1988-11-04 GR GR880100751A patent/GR1000263B/el unknown
- 1988-11-04 MX MX1366588A patent/MX13665A/es unknown
- 1988-11-04 EP EP19880310395 patent/EP0315467A3/en not_active Withdrawn
- 1988-11-04 DK DK616088A patent/DK616088A/da not_active Application Discontinuation
- 1988-11-04 CA CA000582326A patent/CA1336003C/en not_active Expired - Fee Related
- 1988-11-05 CN CN88107693A patent/CN1020897C/zh not_active Expired - Fee Related
- 1988-11-05 KR KR1019880014552A patent/KR970008156B1/ko not_active IP Right Cessation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2410796A (en) * | 1942-04-11 | 1946-11-05 | May & Baker Ltd | Soluble amidine salts |
US2425221A (en) * | 1942-07-27 | 1947-08-05 | May & Baker Ltd | Production of amidine salts |
GB575145A (en) * | 1944-02-23 | 1946-02-05 | May & Baker Ltd | Improvements in or relating to the preparation of amidine salts |
Non-Patent Citations (1)
Title |
---|
CLAIMS SEARCHED: ALL * |
Also Published As
Publication number | Publication date |
---|---|
NO884881L (no) | 1989-05-08 |
KR970008156B1 (ko) | 1997-05-21 |
AU2447688A (en) | 1989-05-11 |
EP0315467A2 (en) | 1989-05-10 |
IN168530B (el) | 1991-04-20 |
IL88159A (en) | 1994-04-12 |
FI885020A0 (fi) | 1988-11-01 |
AU618762B2 (en) | 1992-01-09 |
DK616088A (da) | 1989-05-07 |
FI885020A (fi) | 1989-05-07 |
NO171723B (no) | 1993-01-18 |
DK616088D0 (da) | 1988-11-04 |
EP0315467A3 (en) | 1990-09-26 |
JPH02150A (ja) | 1990-01-05 |
KR890007723A (ko) | 1989-07-05 |
MX13665A (es) | 1993-12-01 |
CN1033046A (zh) | 1989-05-24 |
NO884881D0 (no) | 1988-11-02 |
BR8805759A (pt) | 1989-07-25 |
NO171723C (no) | 1993-04-28 |
CA1336003C (en) | 1995-06-20 |
IL88159A0 (en) | 1989-06-30 |
CN1020897C (zh) | 1993-05-26 |
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