GB997475A - Improvements in or relating to sulphonamides - Google Patents

Improvements in or relating to sulphonamides

Info

Publication number
GB997475A
GB997475A GB3884961A GB3884961A GB997475A GB 997475 A GB997475 A GB 997475A GB 3884961 A GB3884961 A GB 3884961A GB 3884961 A GB3884961 A GB 3884961A GB 997475 A GB997475 A GB 997475A
Authority
GB
United Kingdom
Prior art keywords
halo
reducing
nitro
sulphamoyl
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3884961A
Inventor
Ernst Jucker
Adolf J Lindenmann
John Gmuender
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent Ltd
Sandoz AG
Original Assignee
Sandoz Patent Ltd
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Patent Ltd, Sandoz AG filed Critical Sandoz Patent Ltd
Publication of GB997475A publication Critical patent/GB997475A/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention comprises compounds of the formula <FORM:0997475/C2/1> and acid addition salts thereof, wherein "Hal" represents a halogen atom, e.g. Cl, Br or F, and their preparation by diazotizing a 4-halo-3-sulphamoyl aniline, reducing by a method known to be capable of reducing a nitro compound to the corresponding amino compound, e.g. with stannous chloride and hydrochloric acid or with an alkali-metal bisulphite, and if desired, converting to an acid addition salt. 4 - Halo - 3 - sulphamoyl anilines used as starting materials are made by reducing the corresponding 3 - nitro - 6 - halo - benzenesulphonamide. 3 - Nitro - 6 - fluoro and 6 - iodobenzenesulphonamide are made by chlorosulphonating p - fluoro - or p - iodo - nitrobenzene and reacting the product with ammonia. Pharmaceutical preparations having diuretic or saliuretic activity comprises the above compounds of the invention and an inert carrier.
GB3884961A 1960-11-11 1961-10-31 Improvements in or relating to sulphonamides Expired GB997475A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1267660A CH383400A (en) 1960-11-11 1960-11-11 Process for the preparation of new hydrazine derivatives

Publications (1)

Publication Number Publication Date
GB997475A true GB997475A (en) 1965-07-07

Family

ID=4385352

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3884961A Expired GB997475A (en) 1960-11-11 1961-10-31 Improvements in or relating to sulphonamides

Country Status (3)

Country Link
CH (1) CH383400A (en)
ES (1) ES271861A1 (en)
GB (1) GB997475A (en)

Also Published As

Publication number Publication date
ES271861A1 (en) 1962-06-16
CH383400A (en) 1964-10-31

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