GB997475A - Improvements in or relating to sulphonamides - Google Patents
Improvements in or relating to sulphonamidesInfo
- Publication number
- GB997475A GB997475A GB3884961A GB3884961A GB997475A GB 997475 A GB997475 A GB 997475A GB 3884961 A GB3884961 A GB 3884961A GB 3884961 A GB3884961 A GB 3884961A GB 997475 A GB997475 A GB 997475A
- Authority
- GB
- United Kingdom
- Prior art keywords
- halo
- reducing
- nitro
- sulphamoyl
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention comprises compounds of the formula <FORM:0997475/C2/1> and acid addition salts thereof, wherein "Hal" represents a halogen atom, e.g. Cl, Br or F, and their preparation by diazotizing a 4-halo-3-sulphamoyl aniline, reducing by a method known to be capable of reducing a nitro compound to the corresponding amino compound, e.g. with stannous chloride and hydrochloric acid or with an alkali-metal bisulphite, and if desired, converting to an acid addition salt. 4 - Halo - 3 - sulphamoyl anilines used as starting materials are made by reducing the corresponding 3 - nitro - 6 - halo - benzenesulphonamide. 3 - Nitro - 6 - fluoro and 6 - iodobenzenesulphonamide are made by chlorosulphonating p - fluoro - or p - iodo - nitrobenzene and reacting the product with ammonia. Pharmaceutical preparations having diuretic or saliuretic activity comprises the above compounds of the invention and an inert carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1267660A CH383400A (en) | 1960-11-11 | 1960-11-11 | Process for the preparation of new hydrazine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB997475A true GB997475A (en) | 1965-07-07 |
Family
ID=4385352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3884961A Expired GB997475A (en) | 1960-11-11 | 1961-10-31 | Improvements in or relating to sulphonamides |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH383400A (en) |
ES (1) | ES271861A1 (en) |
GB (1) | GB997475A (en) |
-
1960
- 1960-11-11 CH CH1267660A patent/CH383400A/en unknown
-
1961
- 1961-10-31 GB GB3884961A patent/GB997475A/en not_active Expired
- 1961-11-09 ES ES0271861A patent/ES271861A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES271861A1 (en) | 1962-06-16 |
CH383400A (en) | 1964-10-31 |
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