GB996207A - Improved vitamin a compositions - Google Patents
Improved vitamin a compositionsInfo
- Publication number
- GB996207A GB996207A GB3978/63A GB397863A GB996207A GB 996207 A GB996207 A GB 996207A GB 3978/63 A GB3978/63 A GB 3978/63A GB 397863 A GB397863 A GB 397863A GB 996207 A GB996207 A GB 996207A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- ester
- fatty acid
- compositions
- sorbitan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Dispersing compositions comprise (1) a polyoxyethylene derivative of a monoester of sorbitan with a higher fatty acid having from 16 to 18 carbon atoms and (2) a lower polyethylene glycol having an average molecular weight in the range of from 200 to 600, the ratio by weight of said polyoxyethylene ester (1) to said glycol, (2) being from 4 : 3 to 9 : 1 respectively. Suitable sorbitan ester derivatives are the polyoxyethylene derivatives of sorbitan monopalmitate, sorbitan monooleate and sorbitan monostearate. Polyethylene glycols specified are those having average molecular weight of 200, 300, 400 and 600. The dispersing compositions are used for preparing rapidly water-dispersible Vitamin A fatty acid ester compositions (see Division A5).ALSO:A stable, readily water-dispersible Vitamin A ester composition comprises a Vitamin A higher fatty acid ester, wherein the acyl moiety of the ester has at least eight carbon atoms, and in admixture therewith and as dispersing agent therefor a mixture of (1) a polyoxyethylene derivative of a monoester of sorbitan with a higher fatty acid having from 16 to 18 carbon atoms and (2) a lower polyethylene glycol having an average molecular weight that is in the range of 200 to 600, said Vitamin A ester being present in said composition up to 20% by weight of the total and the ratio by weight of (1) to (2) being from 4 : 3 to 9 : 1 when said Vitamin A concentration is below 10% and from 4 : 3 to 5 : 1 when said Vitamin A concentration is at least 10%. The preferred Vitamin A esters are Vitamin A palmitate, Vitamin A corn oil fatty acid esters and Vitamin A coconut oil fatty acid esters. Sweetening and flavouring agents and preservatives such as methyl and propyl paraben may be added to the compositions. The compositions are used to form stable, aqueous Vitamin A solutions and may also be employed in the form of gelatine capsules, and in aqueous dispersions containing also water-soluble vitamins.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18374762A | 1962-03-30 | 1962-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB996207A true GB996207A (en) | 1965-06-23 |
Family
ID=22674128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3978/63A Expired GB996207A (en) | 1962-03-30 | 1963-01-31 | Improved vitamin a compositions |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH429411A (en) |
| FR (1) | FR2960M (en) |
| GB (1) | GB996207A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4170229A (en) * | 1978-01-16 | 1979-10-09 | Dominion Pharmacal, Inc. | Method for improved health care of hair and scalp using a vitamin A aqueous emulsion |
| CN106667920A (en) * | 2016-12-29 | 2017-05-17 | 陕西科技大学 | Vitamin A nanoparticle and preparation method thereof |
| CN115515566A (en) * | 2020-02-11 | 2022-12-23 | 艾德文治疗公司 | Compositions of vitamin A palmitate, processes for their preparation, uses and methods including them |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422127A (en) * | 1992-12-21 | 1995-06-06 | Bristol-Myers Squibb Company | Nutritional compositions containing vitamin D esters |
| US6248354B1 (en) * | 1999-03-04 | 2001-06-19 | Allergan Sales, Inc. | Capsule system |
-
1963
- 1963-01-30 FR FR923223A patent/FR2960M/en active Active
- 1963-01-31 GB GB3978/63A patent/GB996207A/en not_active Expired
- 1963-03-07 CH CH289563A patent/CH429411A/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4170229A (en) * | 1978-01-16 | 1979-10-09 | Dominion Pharmacal, Inc. | Method for improved health care of hair and scalp using a vitamin A aqueous emulsion |
| CN106667920A (en) * | 2016-12-29 | 2017-05-17 | 陕西科技大学 | Vitamin A nanoparticle and preparation method thereof |
| CN115515566A (en) * | 2020-02-11 | 2022-12-23 | 艾德文治疗公司 | Compositions of vitamin A palmitate, processes for their preparation, uses and methods including them |
Also Published As
| Publication number | Publication date |
|---|---|
| CH429411A (en) | 1967-01-31 |
| FR2960M (en) | 1964-11-30 |
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