GB988635A - Novel benzodiazepine derivatives and a process for the manufacture thereof - Google Patents

Novel benzodiazepine derivatives and a process for the manufacture thereof

Info

Publication number
GB988635A
GB988635A GB40976/62A GB4097662A GB988635A GB 988635 A GB988635 A GB 988635A GB 40976/62 A GB40976/62 A GB 40976/62A GB 4097662 A GB4097662 A GB 4097662A GB 988635 A GB988635 A GB 988635A
Authority
GB
United Kingdom
Prior art keywords
general formula
acid addition
pharmaceutical preparations
manufacture
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB40976/62A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US149527A external-priority patent/US3136815A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB988635A publication Critical patent/GB988635A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB40976/62A 1961-11-02 1962-10-30 Novel benzodiazepine derivatives and a process for the manufacture thereof Expired GB988635A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US149527A US3136815A (en) 1959-12-10 1961-11-02 Amino substituted benzophenone oximes and derivatives thereof

Publications (1)

Publication Number Publication Date
GB988635A true GB988635A (en) 1965-04-07

Family

ID=22530691

Family Applications (2)

Application Number Title Priority Date Filing Date
GB40975/62A Expired GB988634A (en) 1961-11-02 1962-10-30 Novel benzodiazepine derivatives and a process for the manufacture thereof
GB40976/62A Expired GB988635A (en) 1961-11-02 1962-10-30 Novel benzodiazepine derivatives and a process for the manufacture thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB40975/62A Expired GB988634A (en) 1961-11-02 1962-10-30 Novel benzodiazepine derivatives and a process for the manufacture thereof

Country Status (8)

Country Link
BE (2) BE624169A (de)
BR (1) BR6244259D0 (de)
CH (2) CH420176A (de)
DK (2) DK116365B (de)
ES (2) ES282087A1 (de)
FR (1) FR2979M (de)
GB (2) GB988634A (de)
SE (2) SE301980B (de)

Also Published As

Publication number Publication date
SE301980B (de) 1968-07-01
BE624168A (fr) 1963-04-29
DK116287B (da) 1969-12-29
CH420177A (de) 1966-09-15
GB988634A (en) 1965-04-07
DK116365B (da) 1970-01-05
SE302126B (de) 1968-07-08
BE624169A (fr) 1963-04-29
FR2979M (fr) 1964-12-07
DE1445865A1 (de) 1969-03-13
ES282087A1 (es) 1963-03-16
CH420176A (de) 1966-09-15
DE1445866A1 (de) 1969-03-13
BR6244259D0 (pt) 1973-05-24
ES282088A1 (es) 1963-03-16

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