DK116287B - Fremgangsmåde til fremstilling af 4-alkyl- eller 4-alkenyl-5-aryl-1,4-benzodiazepin-2-oner eller kvaternære ammoniumforbindelser eller salte deraf. - Google Patents

Fremgangsmåde til fremstilling af 4-alkyl- eller 4-alkenyl-5-aryl-1,4-benzodiazepin-2-oner eller kvaternære ammoniumforbindelser eller salte deraf.

Info

Publication number
DK116287B
DK116287B DK468762AA DK468762A DK116287B DK 116287 B DK116287 B DK 116287B DK 468762A A DK468762A A DK 468762AA DK 468762 A DK468762 A DK 468762A DK 116287 B DK116287 B DK 116287B
Authority
DK
Denmark
Prior art keywords
benzodiazepin
alkenyl
aryl
ones
salts
Prior art date
Application number
DK468762AA
Other languages
English (en)
Inventor
E Reeder
L Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US149527A external-priority patent/US3136815A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK116287B publication Critical patent/DK116287B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK468762AA 1961-11-02 1962-10-30 Fremgangsmåde til fremstilling af 4-alkyl- eller 4-alkenyl-5-aryl-1,4-benzodiazepin-2-oner eller kvaternære ammoniumforbindelser eller salte deraf. DK116287B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US149527A US3136815A (en) 1959-12-10 1961-11-02 Amino substituted benzophenone oximes and derivatives thereof

Publications (1)

Publication Number Publication Date
DK116287B true DK116287B (da) 1969-12-29

Family

ID=22530691

Family Applications (2)

Application Number Title Priority Date Filing Date
DK468862AA DK116365B (da) 1961-11-02 1962-10-30 Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater eller salte deraf.
DK468762AA DK116287B (da) 1961-11-02 1962-10-30 Fremgangsmåde til fremstilling af 4-alkyl- eller 4-alkenyl-5-aryl-1,4-benzodiazepin-2-oner eller kvaternære ammoniumforbindelser eller salte deraf.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK468862AA DK116365B (da) 1961-11-02 1962-10-30 Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater eller salte deraf.

Country Status (8)

Country Link
BE (2) BE624169A (da)
BR (1) BR6244259D0 (da)
CH (2) CH420176A (da)
DK (2) DK116365B (da)
ES (2) ES282087A1 (da)
FR (1) FR2979M (da)
GB (2) GB988634A (da)
SE (2) SE301980B (da)

Also Published As

Publication number Publication date
SE301980B (da) 1968-07-01
BE624168A (fr) 1963-04-29
CH420177A (de) 1966-09-15
GB988634A (en) 1965-04-07
DK116365B (da) 1970-01-05
SE302126B (da) 1968-07-08
BE624169A (fr) 1963-04-29
GB988635A (en) 1965-04-07
FR2979M (fr) 1964-12-07
DE1445865A1 (de) 1969-03-13
ES282087A1 (es) 1963-03-16
CH420176A (de) 1966-09-15
DE1445866A1 (de) 1969-03-13
BR6244259D0 (pt) 1973-05-24
ES282088A1 (es) 1963-03-16

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