GB985635A - Guanidine derivatives and process for their production - Google Patents
Guanidine derivatives and process for their productionInfo
- Publication number
- GB985635A GB985635A GB31478/63A GB3147863A GB985635A GB 985635 A GB985635 A GB 985635A GB 31478/63 A GB31478/63 A GB 31478/63A GB 3147863 A GB3147863 A GB 3147863A GB 985635 A GB985635 A GB 985635A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- cyanomethyl
- aminoethyl
- propylamines
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002357 guanidines Chemical class 0.000 title abstract 2
- 229940083094 guanine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000006557 (C2-C5) alkylene group Chemical group 0.000 abstract 1
- CSKIVKHMWJBLAM-UHFFFAOYSA-N 2-[methyl(3-phenylpropyl)amino]acetonitrile Chemical compound N#CCN(C)CCCC1=CC=CC=C1 CSKIVKHMWJBLAM-UHFFFAOYSA-N 0.000 abstract 1
- CEESDXDKUVUUSO-UHFFFAOYSA-N CC(CC1=CC=CC=C1)N(C)CCN Chemical class CC(CC1=CC=CC=C1)N(C)CCN CEESDXDKUVUUSO-UHFFFAOYSA-N 0.000 abstract 1
- ZPGIJFIOAHGKGH-UHFFFAOYSA-N CN(CCN)CCCC1=C(Cl)C=CC=C1 Chemical class CN(CCN)CCCC1=C(Cl)C=CC=C1 ZPGIJFIOAHGKGH-UHFFFAOYSA-N 0.000 abstract 1
- ZLZCZYJZUVGDGR-UHFFFAOYSA-N N'-[3-(2-bromophenyl)propyl]-N'-methylethane-1,2-diamine Chemical class NCCN(C)CCCC1=C(C=CC=C1)Br ZLZCZYJZUVGDGR-UHFFFAOYSA-N 0.000 abstract 1
- JZNKLPVTSOPVNQ-UHFFFAOYSA-N N'-[3-(4-chlorophenyl)propyl]-N'-methylethane-1,2-diamine Chemical class NCCN(C)CCCC1=CC=C(C=C1)Cl JZNKLPVTSOPVNQ-UHFFFAOYSA-N 0.000 abstract 1
- VCFOIXZNCULVIA-UHFFFAOYSA-N N'-[3-(4-methoxyphenyl)propyl]-N'-methylethane-1,2-diamine Chemical class COC1=CC=C(CCCN(C)CCN)C=C1 VCFOIXZNCULVIA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 125000002795 guanidino group Chemical group C(N)(=N)N* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- CPCHVLBDLZEKTD-UHFFFAOYSA-N n'-(2-phenylethyl)ethane-1,2-diamine Chemical class NCCNCCC1=CC=CC=C1 CPCHVLBDLZEKTD-UHFFFAOYSA-N 0.000 abstract 1
- GKISERHGRUXARH-UHFFFAOYSA-N n'-ethyl-n'-(3-phenylpropyl)ethane-1,2-diamine Chemical class NCCN(CC)CCCC1=CC=CC=C1 GKISERHGRUXARH-UHFFFAOYSA-N 0.000 abstract 1
- MVJJQXOQJKAJDN-UHFFFAOYSA-N n'-methyl-n'-(3-phenylpropyl)ethane-1,2-diamine Chemical compound NCCN(C)CCCC1=CC=CC=C1 MVJJQXOQJKAJDN-UHFFFAOYSA-N 0.000 abstract 1
- UAVVEFHZIGDBJF-UHFFFAOYSA-N n'-methyl-n'-(3-phenylpropyl)propane-1,3-diamine Chemical class NCCCN(C)CCCC1=CC=CC=C1 UAVVEFHZIGDBJF-UHFFFAOYSA-N 0.000 abstract 1
- MLHBZVFOTDJTPK-UHFFFAOYSA-N n-methyl-3-phenylpropan-1-amine Chemical compound CNCCCC1=CC=CC=C1 MLHBZVFOTDJTPK-UHFFFAOYSA-N 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003141 primary amines Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9136/62A SE321464B (enExample) | 1962-08-23 | 1962-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB985635A true GB985635A (en) | 1965-03-10 |
Family
ID=20275920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31478/63A Expired GB985635A (en) | 1962-08-23 | 1963-08-09 | Guanidine derivatives and process for their production |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3211789A (enExample) |
| AT (1) | AT244347B (enExample) |
| DK (1) | DK113496B (enExample) |
| FI (1) | FI40282B (enExample) |
| GB (1) | GB985635A (enExample) |
| SE (1) | SE321464B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0330629A3 (en) * | 1988-02-24 | 1990-10-31 | Consiglio Nazionale Delle Ricerche | Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4680300A (en) * | 1985-01-10 | 1987-07-14 | Syntex (U.S.A.) Inc. | Anti-inflammatory guanidines |
| IL89997A0 (en) * | 1988-04-25 | 1989-12-15 | Lilly Co Eli | Propanamine derivatives |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2672029A (en) * | 1952-03-18 | 1954-03-16 | Gen Motors Corp | Removable unit in refrigerating apparatus |
| US2851457A (en) * | 1956-04-09 | 1958-09-09 | Searle & Co | Amidinoalkylbenzothiazinones and processes |
| US2903453A (en) * | 1956-10-09 | 1959-09-08 | Lakeside Lab Inc | Quaternary ammonium salts of aminoalcohol esters of n-alkylpiperidine carboxylic acids |
| US2951078A (en) * | 1957-08-21 | 1960-08-30 | Lakeside Lab Inc | 2-(aminoalkylamino)-methylpyrrolidines |
| US2881175A (en) * | 1958-04-25 | 1959-04-07 | Upjohn Co | 1,1 bis (p-amino phenyl) alkanones |
| US3027370A (en) * | 1958-06-20 | 1962-03-27 | Geigy Ag J R | Derivatives of guanidine |
| US3006913A (en) * | 1959-06-10 | 1961-10-31 | Ciba Pharm Prod Inc | Process for preparing (n,n-alkylene-imino)-lower alkyl-guanidines |
| US2928829A (en) * | 1959-08-31 | 1960-03-15 | Ciba Pharm Prod Inc | Alkyleneimino-lower alkyl-guanidines |
-
1962
- 1962-08-23 SE SE9136/62A patent/SE321464B/xx unknown
- 1962-12-27 US US247553A patent/US3211789A/en not_active Expired - Lifetime
-
1963
- 1963-08-09 GB GB31478/63A patent/GB985635A/en not_active Expired
- 1963-08-09 DK DK381663AA patent/DK113496B/da unknown
- 1963-08-19 FI FI1588/63A patent/FI40282B/fi active
- 1963-08-23 AT AT678863A patent/AT244347B/de active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0330629A3 (en) * | 1988-02-24 | 1990-10-31 | Consiglio Nazionale Delle Ricerche | Guanidine derivatives having hypotensive activity, composition containing them, and process for obtaining them |
Also Published As
| Publication number | Publication date |
|---|---|
| SE321464B (enExample) | 1970-03-09 |
| US3211789A (en) | 1965-10-12 |
| FI40282B (enExample) | 1968-09-02 |
| AT244347B (de) | 1965-12-27 |
| DK113496B (da) | 1969-03-31 |
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