GB985610A - New sulphanilamide derivatives and processes for their production - Google Patents
New sulphanilamide derivatives and processes for their productionInfo
- Publication number
- GB985610A GB985610A GB48504/62A GB4850462A GB985610A GB 985610 A GB985610 A GB 985610A GB 48504/62 A GB48504/62 A GB 48504/62A GB 4850462 A GB4850462 A GB 4850462A GB 985610 A GB985610 A GB 985610A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyrimidine
- amino
- trichloro
- dimethoxy
- chlorine atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- FDDDEECHVMSUSB-UHFFFAOYSA-N sulfanilamide Chemical class NC1=CC=C(S(N)(=O)=O)C=C1 FDDDEECHVMSUSB-UHFFFAOYSA-N 0.000 title abstract 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 4
- -1 acetylamino, benzylideneamino Chemical group 0.000 abstract 4
- 125000003277 amino group Chemical group 0.000 abstract 3
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 3
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- QUSNBJAOOMFDIB-UHFFFAOYSA-N Ethylamine Chemical compound CCN QUSNBJAOOMFDIB-UHFFFAOYSA-N 0.000 abstract 2
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLUPDMFOQRYWOO-UHFFFAOYSA-N 2,4,5-trichloro-6-methylsulfanylpyrimidine Chemical compound CSC1=NC(Cl)=NC(Cl)=C1Cl XLUPDMFOQRYWOO-UHFFFAOYSA-N 0.000 abstract 1
- GLDNZPLPEYLLNS-UHFFFAOYSA-N 2,5,6-trichloropyrimidin-4-amine Chemical compound NC1=NC(Cl)=NC(Cl)=C1Cl GLDNZPLPEYLLNS-UHFFFAOYSA-N 0.000 abstract 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 1
- BFSVOASYOCHEOV-UHFFFAOYSA-N 2-diethylaminoethanol Chemical compound CCN(CC)CCO BFSVOASYOCHEOV-UHFFFAOYSA-N 0.000 abstract 1
- VDLIXJPAQJWACS-UHFFFAOYSA-N 4,5,6-trichloro-2-methoxypyrimidine Chemical compound COC1=NC(Cl)=C(Cl)C(Cl)=N1 VDLIXJPAQJWACS-UHFFFAOYSA-N 0.000 abstract 1
- GRDXCFKBQWDAJH-UHFFFAOYSA-N 4-acetamidobenzenesulfonyl chloride Chemical compound CC(=O)NC1=CC=C(S(Cl)(=O)=O)C=C1 GRDXCFKBQWDAJH-UHFFFAOYSA-N 0.000 abstract 1
- CUYLTSVFIINTNY-UHFFFAOYSA-N 5-chloro-2,4-dimethoxy-6-methylsulfanylpyrimidine Chemical compound CSC1=NC(=NC(=C1Cl)OC)OC CUYLTSVFIINTNY-UHFFFAOYSA-N 0.000 abstract 1
- QTYYTSYTVAHWNK-UHFFFAOYSA-N 5-chloro-2,4-dimethoxy-6-methylsulfonylpyrimidine Chemical compound CS(=O)(=O)C1=NC(=NC(=C1Cl)OC)OC QTYYTSYTVAHWNK-UHFFFAOYSA-N 0.000 abstract 1
- QYSNPJBHHFSLFG-UHFFFAOYSA-N 5-chloro-2,6-dimethoxypyrimidin-4-amine Chemical compound COC1=NC(N)=C(Cl)C(OC)=N1 QYSNPJBHHFSLFG-UHFFFAOYSA-N 0.000 abstract 1
- NZRZAYFIPTYEAV-UHFFFAOYSA-N 5-chloro-4-hydroxy-2-methoxy-1H-pyrimidin-6-one Chemical compound ClC=1C(=NC(=NC1O)OC)O NZRZAYFIPTYEAV-UHFFFAOYSA-N 0.000 abstract 1
- KHBQMWCZKVMBLN-UHFFFAOYSA-N Benzenesulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1 KHBQMWCZKVMBLN-UHFFFAOYSA-N 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- SRSXLGNVWSONIS-UHFFFAOYSA-N benzenesulfonic acid Chemical compound OS(=O)(=O)C1=CC=CC=C1 SRSXLGNVWSONIS-UHFFFAOYSA-N 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000000973 chemotherapeutic effect Effects 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000011777 magnesium Substances 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- WYYGKEQESDLJCE-UHFFFAOYSA-N n-ethylethanamine;morpholine Chemical compound CCNCC.C1COCCN1 WYYGKEQESDLJCE-UHFFFAOYSA-N 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- OYRRZWATULMEPF-UHFFFAOYSA-N pyrimidin-4-amine Chemical compound NC1=CC=NC=N1 OYRRZWATULMEPF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B43/00—Preparation of azo dyes from other azo compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1512261A CH394218A (de) | 1961-12-29 | 1961-12-29 | Verfahren zur Herstellung von neuen Sulfanilamiden |
Publications (1)
Publication Number | Publication Date |
---|---|
GB985610A true GB985610A (en) | 1965-03-10 |
Family
ID=4406523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB48504/62A Expired GB985610A (en) | 1961-12-29 | 1962-12-21 | New sulphanilamide derivatives and processes for their production |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE626639A (enrdf_load_stackoverflow) |
CH (1) | CH394218A (enrdf_load_stackoverflow) |
DE (1) | DE1233404B (enrdf_load_stackoverflow) |
ES (2) | ES283769A1 (enrdf_load_stackoverflow) |
FR (2) | FR1499106A (enrdf_load_stackoverflow) |
GB (1) | GB985610A (enrdf_load_stackoverflow) |
NL (2) | NL287276A (enrdf_load_stackoverflow) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE926131C (de) * | 1951-06-24 | 1955-04-07 | Nordmark Werke Gmbh | Verfahren zur Herstellung von 4-(p-Aminobenzolsulfoyl)-amino-2-alkyl-6-alkoxypyrimidinen |
-
0
- NL NL121629D patent/NL121629C/xx active
- NL NL287276D patent/NL287276A/xx unknown
- BE BE626639D patent/BE626639A/xx unknown
-
1961
- 1961-12-29 CH CH1512261A patent/CH394218A/de unknown
-
1962
- 1962-12-21 GB GB48504/62A patent/GB985610A/en not_active Expired
- 1962-12-28 FR FR919955A patent/FR1499106A/fr not_active Expired
- 1962-12-28 DE DEG36745A patent/DE1233404B/de active Pending
- 1962-12-28 ES ES283769A patent/ES283769A1/es not_active Expired
- 1962-12-28 ES ES283770A patent/ES283770A1/es not_active Expired
-
1963
- 1963-03-27 FR FR929403A patent/FR2777M/fr active Active
Also Published As
Publication number | Publication date |
---|---|
ES283769A1 (es) | 1963-07-01 |
NL121629C (enrdf_load_stackoverflow) | |
BE626639A (enrdf_load_stackoverflow) | |
NL287276A (enrdf_load_stackoverflow) | |
ES283770A1 (es) | 1963-07-01 |
DE1233404B (de) | 1967-02-02 |
CH394218A (de) | 1965-06-30 |
FR2777M (fr) | 1964-09-07 |
FR1499106A (fr) | 1967-10-27 |
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