GB981092A - Pharmaceutical compositions containing quaternary ammonium compounds - Google Patents

Pharmaceutical compositions containing quaternary ammonium compounds

Info

Publication number
GB981092A
GB981092A GB2195060A GB2195060A GB981092A GB 981092 A GB981092 A GB 981092A GB 2195060 A GB2195060 A GB 2195060A GB 2195060 A GB2195060 A GB 2195060A GB 981092 A GB981092 A GB 981092A
Authority
GB
United Kingdom
Prior art keywords
quaternary ammonium
ammonium compounds
pharmaceutical compositions
cation
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2195060A
Inventor
Frederick Charles Copp
Geoffrey George Coker
Albert Reginald Elphick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB2195060A priority Critical patent/GB981092A/en
Publication of GB981092A publication Critical patent/GB981092A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Quaternary ammonium compounds having a cation of general formula <FORM:0981092/C2/1> wherein R1 and R2 are methyl, ethyl or 2-hydroxyethyl groups, are prepared by quaternization of an appropriate tertiary amine (which may be prepared in situ from secondary or primary amines), optionally followed by double decomposition of the salts.ALSO:Pharmaceutical compositions comprise quaternary ammonium compounds containing a cation of general formula <FORM:0981092/A5-A6/1> wherein R1 and R2 are each a methyl, ethyl or 2-hydroxyethyl group and pharmaceutically acceptable carriers in discrete units each containing a predetermined amount or concentration of the drug. Compositions in general are described in the form of tablets, powders, granules, capsules, cachets, syrups, suspensions, emulsions, solutions, suppositories and pessaries. The compounds depress sympathetic nerve function.
GB2195060A 1960-06-23 1960-06-23 Pharmaceutical compositions containing quaternary ammonium compounds Expired GB981092A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2195060A GB981092A (en) 1960-06-23 1960-06-23 Pharmaceutical compositions containing quaternary ammonium compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2195060A GB981092A (en) 1960-06-23 1960-06-23 Pharmaceutical compositions containing quaternary ammonium compounds

Publications (1)

Publication Number Publication Date
GB981092A true GB981092A (en) 1965-01-20

Family

ID=10171483

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2195060A Expired GB981092A (en) 1960-06-23 1960-06-23 Pharmaceutical compositions containing quaternary ammonium compounds

Country Status (1)

Country Link
GB (1) GB981092A (en)

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