GB971615A - Mandelic acid esters and process for preparing them - Google Patents
Mandelic acid esters and process for preparing themInfo
- Publication number
- GB971615A GB971615A GB13942/63A GB1394263A GB971615A GB 971615 A GB971615 A GB 971615A GB 13942/63 A GB13942/63 A GB 13942/63A GB 1394263 A GB1394263 A GB 1394263A GB 971615 A GB971615 A GB 971615A
- Authority
- GB
- United Kingdom
- Prior art keywords
- mandelic acid
- pharmaceutical preparations
- acid addition
- preparing
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QBYIENPQHBMVBV-HFEGYEGKSA-N (2R)-2-hydroxy-2-phenylacetic acid Chemical class O[C@@H](C(O)=O)c1ccccc1.O[C@@H](C(O)=O)c1ccccc1 QBYIENPQHBMVBV-HFEGYEGKSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 formyloxy, acetyloxy Chemical group 0.000 abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF36554A DE1240881B (de) | 1962-04-14 | 1962-04-14 | Verfahren zur Herstellung von basischen Mandelsaeureestern und deren Saeureadditionssalzen |
| DEF0036552 | 1962-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB971615A true GB971615A (en) | 1964-09-30 |
Family
ID=25975296
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13942/63A Expired GB971615A (en) | 1962-04-14 | 1963-04-08 | Mandelic acid esters and process for preparing them |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3330858A (en:Method) |
| AT (1) | AT242121B (en:Method) |
| BE (1) | BE631090A (en:Method) |
| BR (1) | BR6348375D0 (en:Method) |
| CH (1) | CH439312A (en:Method) |
| DE (1) | DE1240881B (en:Method) |
| DK (1) | DK105533C (en:Method) |
| FI (1) | FI40805B (en:Method) |
| FR (2) | FR2842M (en:Method) |
| GB (1) | GB971615A (en:Method) |
| NL (2) | NL291268A (en:Method) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661625A (en) * | 1985-12-02 | 1987-04-28 | Mallinckkodt, Inc. | Synthesis and purification of d-propoxyphene hydrochloride |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1282238A (fr) * | 1959-12-28 | 1962-01-19 | Hoechst Ag | Nouveaux propanols aminés et alcénylamines et leur préparation |
-
0
- BE BE631090D patent/BE631090A/xx unknown
- NL NL133043D patent/NL133043C/xx active
- NL NL291268D patent/NL291268A/xx unknown
-
1962
- 1962-04-14 DE DEF36554A patent/DE1240881B/de active Pending
-
1963
- 1963-04-01 US US269725A patent/US3330858A/en not_active Expired - Lifetime
- 1963-04-08 GB GB13942/63A patent/GB971615A/en not_active Expired
- 1963-04-10 DK DK172063AA patent/DK105533C/da active
- 1963-04-10 BR BR148375/63A patent/BR6348375D0/pt unknown
- 1963-04-10 FI FI0726/63A patent/FI40805B/fi active
- 1963-04-10 CH CH456063A patent/CH439312A/de unknown
- 1963-04-12 AT AT302363A patent/AT242121B/de active
- 1963-07-11 FR FR941112A patent/FR2842M/fr active Active
- 1963-07-11 FR FR941111A patent/FR2841M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AT242121B (de) | 1965-08-25 |
| US3330858A (en) | 1967-07-11 |
| CH439312A (de) | 1967-07-15 |
| BE631090A (en:Method) | |
| FR2841M (fr) | 1964-10-12 |
| FR2842M (fr) | 1964-10-12 |
| DK105533C (da) | 1966-10-10 |
| FI40805B (en:Method) | 1969-02-28 |
| NL291268A (en:Method) | |
| DE1240881B (de) | 1967-05-24 |
| BR6348375D0 (pt) | 1973-08-14 |
| NL133043C (en:Method) |
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