GB9624817D0 - Metalloproteinase inhibitors - Google Patents

Metalloproteinase inhibitors

Info

Publication number
GB9624817D0
GB9624817D0 GBGB9624817.4A GB9624817A GB9624817D0 GB 9624817 D0 GB9624817 D0 GB 9624817D0 GB 9624817 A GB9624817 A GB 9624817A GB 9624817 D0 GB9624817 D0 GB 9624817D0
Authority
GB
United Kingdom
Prior art keywords
metalloproteinase inhibitors
metalloproteinase
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9624817.4A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vernalis R&D Ltd
Original Assignee
British Biotech Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharmaceuticals Ltd filed Critical British Biotech Pharmaceuticals Ltd
Priority to GBGB9624817.4A priority Critical patent/GB9624817D0/en
Publication of GB9624817D0 publication Critical patent/GB9624817D0/en
Priority to EP97945960A priority patent/EP0944597A1/fr
Priority to AU51282/98A priority patent/AU5128298A/en
Priority to PCT/GB1997/003258 priority patent/WO1998023588A1/fr
Priority to JP52443398A priority patent/JP2001509790A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GBGB9624817.4A 1996-11-28 1996-11-28 Metalloproteinase inhibitors Pending GB9624817D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GBGB9624817.4A GB9624817D0 (en) 1996-11-28 1996-11-28 Metalloproteinase inhibitors
EP97945960A EP0944597A1 (fr) 1996-11-28 1997-11-27 Inhibiteurs de metalloproteinases
AU51282/98A AU5128298A (en) 1996-11-28 1997-11-27 Metalloproteinase inhibitors
PCT/GB1997/003258 WO1998023588A1 (fr) 1996-11-28 1997-11-27 Inhibiteurs de metalloproteinases
JP52443398A JP2001509790A (ja) 1996-11-28 1997-11-27 金属タンパク質分解酵素阻害剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9624817.4A GB9624817D0 (en) 1996-11-28 1996-11-28 Metalloproteinase inhibitors

Publications (1)

Publication Number Publication Date
GB9624817D0 true GB9624817D0 (en) 1997-01-15

Family

ID=10803657

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9624817.4A Pending GB9624817D0 (en) 1996-11-28 1996-11-28 Metalloproteinase inhibitors

Country Status (5)

Country Link
EP (1) EP0944597A1 (fr)
JP (1) JP2001509790A (fr)
AU (1) AU5128298A (fr)
GB (1) GB9624817D0 (fr)
WO (1) WO1998023588A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001019796A1 (fr) * 1999-09-16 2001-03-22 Axys Pharmaceuticals, Inc. Composes et compositions pharmaceutiques utilises comme inhibiteurs de la cathepsine s
JP2004523506A (ja) 2000-12-22 2004-08-05 アクシス・ファーマシューティカルズ・インコーポレイテッド カテプシン阻害剤としての新規な化合物と組成物
US7030116B2 (en) 2000-12-22 2006-04-18 Aventis Pharmaceuticals Inc. Compounds and compositions as cathepsin inhibitors
MXPA04002282A (es) 2001-09-14 2005-03-07 Axis Pharmaceutical Inc Nuevos compuestos y preparaciones como inhibidores de la catepsina.
RU2004117877A (ru) 2001-11-14 2006-01-10 Авентис Фармасьютикалз Инк. (Us) Олигопептиды и композиции, содержащие их, в качестве ингибиторов катепсина s
EP1586559A1 (fr) * 2004-04-13 2005-10-19 Cephalon, Inc. Dérivés biarylméthanesulfides, -sulfinyles et -sulfonyles
US7449481B2 (en) 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9323165D0 (en) * 1993-11-10 1994-01-05 Chiros Ltd Compounds
JP3787605B2 (ja) * 1994-10-05 2006-06-21 ダーウィン・ディスカバリー・リミテッド ペプチジル化合物および金属プロテアーゼのインヒビターとしてのその治療的使用
DE69627483T2 (de) * 1995-05-10 2004-04-01 Darwin Discovery Ltd., Slough Peptidartige stoffe, die metalloproteinasen und die tnf-freisetzung hemmen, und ihre therapeutische verwendung
GB9514867D0 (en) * 1995-07-20 1995-09-20 British Biotech Pharm Metalloproteinase inhibitors
GB9607120D0 (en) * 1996-04-04 1996-06-12 Chiroscience Ltd Compounds

Also Published As

Publication number Publication date
JP2001509790A (ja) 2001-07-24
WO1998023588A1 (fr) 1998-06-04
AU5128298A (en) 1998-06-22
EP0944597A1 (fr) 1999-09-29

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