GB961516A - New n-diphenylalkyl-norgranatane derivatives - Google Patents
New n-diphenylalkyl-norgranatane derivativesInfo
- Publication number
- GB961516A GB961516A GB4015/63A GB401563A GB961516A GB 961516 A GB961516 A GB 961516A GB 4015/63 A GB4015/63 A GB 4015/63A GB 401563 A GB401563 A GB 401563A GB 961516 A GB961516 A GB 961516A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- norgranatane
- condensing
- diphenylalkyl
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises compounds of formula: <FORM:0961516/C1/1> wherein X is a hydrogen atom or a hydroxyl group, and Z is a straight or branched-chain alkylene radical having 1 to 4 carbon atoms, acid addition salts thereof, and their preparation by (a) condensing an amine of formula: <FORM:0961516/C1/2> with acetone dicarboxylic acid and glutaric dialdehyde and reducing the pseudopelletierin derivative thus formed, or (b) condensing a halo ketone of formula C6H5 CO-Z-Hal with norgranatane, reacting the N-benzoyl derivative thus obtained with a phenyl magnesium halide or a phenyl-alkali metal compound, and, if desired, dehydrating and hydrogenating the product. The compounds of the invention have anti-tussive properties.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1962B0065780 DE1162847B (en) | 1962-02-02 | 1962-02-02 | Process for the preparation of N-diphenylalkyl-norgranatane and -nortropane derivatives. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB961516A true GB961516A (en) | 1964-06-24 |
Family
ID=6974904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4015/63A Expired GB961516A (en) | 1962-02-02 | 1963-01-31 | New n-diphenylalkyl-norgranatane derivatives |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE627904A (en) |
| CH (2) | CH420167A (en) |
| DE (1) | DE1162847B (en) |
| GB (1) | GB961516A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1219943B (en) * | 1964-06-30 | 1966-06-30 | Boehringer & Soehne Gmbh | Process for the preparation of esters of N- (hydroxyalkyl) -nortropanes or -norgranatanes and their salts |
-
1962
- 1962-02-02 DE DE1962B0065780 patent/DE1162847B/en active Pending
-
1963
- 1963-01-31 GB GB4015/63A patent/GB961516A/en not_active Expired
- 1963-01-31 CH CH931866A patent/CH420167A/en unknown
- 1963-01-31 CH CH118363A patent/CH419141A/en unknown
- 1963-02-01 BE BE627904A patent/BE627904A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH420167A (en) | 1966-09-15 |
| BE627904A (en) | 1963-08-01 |
| CH419141A (en) | 1966-08-31 |
| DE1162847B (en) | 1964-02-13 |
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