GB961342A - ªÏ-di-(pyridyl)-propane derivatives and a process for their production - Google Patents

ªÏ-di-(pyridyl)-propane derivatives and a process for their production

Info

Publication number
GB961342A
GB961342A GB4142661A GB4142661A GB961342A GB 961342 A GB961342 A GB 961342A GB 4142661 A GB4142661 A GB 4142661A GB 4142661 A GB4142661 A GB 4142661A GB 961342 A GB961342 A GB 961342A
Authority
GB
United Kingdom
Prior art keywords
general formula
represent hydrogen
different
same
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4142661A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH, Deutsche Gold und Silber Scheideanstalt filed Critical Degussa GmbH
Publication of GB961342A publication Critical patent/GB961342A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

The invention comprises compounds of the general formula: <FORM:0961342/C1/1> (wherein R1 and R2 are the same or different and represent hydrogen atoms or C1- 4 alkyl groups, Alk represents an alkylene radical containing 2 to 4 carbon atoms of which 1 or 2 carbon atoms form a chain between the NH group and the CH group linking the heterocyclic nuclei, R3 and R4 are the same or different and represent hydrogen atoms or C1- 4 alkyl groups, and R5 and R6 are the same or different and represent hydrogen or halogen atoms or hydroxyl or C1- 4 alkoxy groups) and acid addition salts thereof, and their preparation by reacting a compound of the general formula: <FORM:0961342/C1/2> with a compound of the general formula: <FORM:0961342/C1/3> in the presence of an alkaline condensation agent, optionally followed by acid addition salt formation. The compounds of the invention are central nervous system stimulants and have a coronary-dilating action.
GB4142661A 1960-11-18 1961-11-20 ªÏ-di-(pyridyl)-propane derivatives and a process for their production Expired GB961342A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DED0034752 1960-11-18

Publications (1)

Publication Number Publication Date
GB961342A true GB961342A (en) 1964-06-17

Family

ID=7042326

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4142661A Expired GB961342A (en) 1960-11-18 1961-11-20 ªÏ-di-(pyridyl)-propane derivatives and a process for their production

Country Status (4)

Country Link
BR (1) BR6134189D0 (en)
CH (1) CH414627A (en)
DE (1) DE1445019A1 (en)
GB (1) GB961342A (en)

Also Published As

Publication number Publication date
DE1445019A1 (en) 1968-12-12
CH414627A (en) 1966-06-15
BR6134189D0 (en) 1973-06-12

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