GB948071A - New heterocyclic compounds - Google Patents

New heterocyclic compounds

Info

Publication number
GB948071A
GB948071A GB15048/59A GB1504859A GB948071A GB 948071 A GB948071 A GB 948071A GB 15048/59 A GB15048/59 A GB 15048/59A GB 1504859 A GB1504859 A GB 1504859A GB 948071 A GB948071 A GB 948071A
Authority
GB
United Kingdom
Prior art keywords
group
tetrahydropyridine
trifluoromethylphenyl
prepared
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB15048/59A
Other languages
English (en)
Inventor
William Robert Wragg
Anthony Stanley Fenton Ash
Andrew Malcolm Creighton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Priority to GB15048/59A priority Critical patent/GB948071A/en
Priority to FR825458A priority patent/FR1421208A/fr
Priority to CH493160A priority patent/CH404664A/fr
Priority to FR836260A priority patent/FR223M/fr
Priority to US132551A priority patent/US3209006A/en
Priority to FR905189A priority patent/FR86403E/fr
Priority to FR907494A priority patent/FR39F/fr
Publication of GB948071A publication Critical patent/GB948071A/en
Priority to NL6501492A priority patent/NL6501492A/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB15048/59A 1959-05-01 1959-05-01 New heterocyclic compounds Expired GB948071A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB15048/59A GB948071A (en) 1959-05-01 1959-05-01 New heterocyclic compounds
FR825458A FR1421208A (enExample) 1959-05-01 1960-04-27
CH493160A CH404664A (fr) 1959-05-01 1960-04-29 Procédé de préparation de nouveaux composés hétérocycliques
FR836260A FR223M (fr) 1959-05-01 1960-08-19 Nouveaux composés hétérocycliques, et composition pharmaceutiques qui les continent.
US132551A US3209006A (en) 1959-05-01 1961-08-21 Phenylpiperidine and phenyltetrahydropyridine compounds
FR905189A FR86403E (fr) 1959-05-01 1962-07-26 Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
FR907494A FR39F (fr) 1959-05-01 1962-08-22 Nouveaux composés hétérocycliques et compositions pharmaceutiques qui les contiennent.
NL6501492A NL6501492A (enExample) 1959-05-01 1965-02-05

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB15048/59A GB948071A (en) 1959-05-01 1959-05-01 New heterocyclic compounds

Publications (1)

Publication Number Publication Date
GB948071A true GB948071A (en) 1964-01-29

Family

ID=10052124

Family Applications (1)

Application Number Title Priority Date Filing Date
GB15048/59A Expired GB948071A (en) 1959-05-01 1959-05-01 New heterocyclic compounds

Country Status (5)

Country Link
US (1) US3209006A (enExample)
CH (1) CH404664A (enExample)
FR (1) FR1421208A (enExample)
GB (1) GB948071A (enExample)
NL (1) NL6501492A (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060176A1 (fr) * 1981-03-11 1982-09-15 Sanofi S.A. Trifluorométhylphényltétrahydropyridines substituées à activité anorexigène, un procédé de préparation et compositions pharmaceutiques
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
WO1991008200A1 (en) * 1989-12-01 1991-06-13 Richter Gedeon Vegyészeti Gyár Rt. Novel tetrahydropyridine derivatives, a process for their preparation and pharmaceutical compositions containing such compounds as active agents
EP0372776A3 (en) * 1988-12-02 1991-10-23 Pfizer Inc. Arylpiperidine derivatives
JP2002526493A (ja) * 1998-09-23 2002-08-20 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・（エス．セー．エール．アー．エス） 新規なアミジン誘導体、その製造方法、その医薬としての使用及びこれを含有する医薬組成物

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3329683A (en) * 1963-05-23 1967-07-04 Yoshitomi Pharmaceutical N((4, 4-substituted piperidino) lower alkyl)iminodibenzyl compounds
US3407256A (en) * 1963-05-23 1968-10-22 Yoshitomi Seiyaku Kogyo Kk Psychotherapeutic compositions of n((4,4-substituted piperidino) lower alkyl) iminodibenzyl compounds
US3310566A (en) * 1963-11-18 1967-03-21 American Home Prod Substituted 4-piperidino-butyrophenone oximes
US3424755A (en) * 1964-03-09 1969-01-28 Rolf Denss 4-piperidine-p-fluorobutyrophenones and related compounds
GB1060160A (en) * 1964-08-05 1967-03-01 Allen & Hanburys Ltd 4-phenylpiperidine derivatives
US3476762A (en) * 1966-12-27 1969-11-04 Aldrich Chem Co Inc 4' - dimethylamino - 4 - (4 - hydroxy-4-phenyl piperidino)butyrophenones and 4 - (4-phenyl-4-hydroxy - piperidino)-1,1-ethylenedioxy - 1 - (4 - dimethylaminophenyl)butanes
US3511915A (en) * 1967-01-24 1970-05-12 Geigy Chem Corp Method of producing an antitussive effect
US3423406A (en) * 1967-05-08 1969-01-21 Ciba Geigy Corp N-alkenyl-3-aralkyl-alkyleneimines
US3509166A (en) * 1968-01-15 1970-04-28 American Cyanamid Co Tetrahydro-pyridine derivatives of benzamide
US3865944A (en) * 1972-02-10 1975-02-11 Stauffer Chemical Co Tetrahydropyridine insect repellent
JPS5755714B2 (enExample) * 1972-03-18 1982-11-25
JPS5922702B2 (ja) * 1975-07-17 1984-05-28 住友化学工業株式会社 新規オルト−ニトロブチロフエノン誘導体の製造法
JPS5922703B2 (ja) * 1975-07-18 1984-05-28 住友化学工業株式会社 オルト−アミノブチロフエノン誘導体の新規な製造法
JPS5756474B2 (enExample) * 1973-05-26 1982-11-30
JPS5083376A (enExample) * 1973-11-28 1975-07-05
DE2718405A1 (de) * 1977-04-26 1978-11-02 Boehringer Sohn Ingelheim Neue n- eckige klammer auf 1-(3-benzoylpropyl)-4-piperidyl eckige klammer zu -sulfonsaeureamide und verfahren zu deren herstellung
AU3366389A (en) * 1988-03-25 1989-10-16 Marion Laboratories, Inc. Piperidine ring modified phencyclidine analogs as anticonvulsants
CA2071897A1 (en) * 1989-12-28 1991-06-29 Richard A. Glennon Sigma receptor ligands and the use thereof
HU209573B (en) * 1990-12-13 1994-08-29 Richter Gedeon Vegyeszet Process for producing of 1,2,3,6-tetrahydropyridine derivatives and pharmaceutical compositions comprising these substances
GB9100505D0 (en) 1991-01-10 1991-02-20 Shell Int Research Piperidine derivatives
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
US5364867A (en) * 1992-11-30 1994-11-15 Sterling Winthrop Inc. 4-phenylpiperdine agents for treating cns disorders
AU7177694A (en) * 1993-06-23 1995-01-17 Cambridge Neuroscience, Inc. Sigma receptor ligands and the use thereof
EP2667805B1 (en) 2011-01-28 2023-04-05 The General Hospital Corporation Apparatus and method for tissue biopsy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2973365A (en) * 1959-04-09 1961-02-28 Paul A J Janssen 1-aroylalkyl-4-aryl-1, 2, 3, 6-tetrahydropyridines
US3080372A (en) * 1960-03-25 1963-03-05 Res Lab Dr C Janssen 1-aroylalkyl-4-arylpiperidine derivatives

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0060176A1 (fr) * 1981-03-11 1982-09-15 Sanofi S.A. Trifluorométhylphényltétrahydropyridines substituées à activité anorexigène, un procédé de préparation et compositions pharmaceutiques
FR2501682A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant
US4472408A (en) * 1981-03-11 1984-09-18 Sanofi Substituted trifluoromethylphenyltetrahydropyridines having an anorectic activity
US4602024A (en) * 1981-03-11 1986-07-22 Sanofi Substituted trifluoromethylphenyltetrahydropyridines having a cyano substituent and an anorectic activity, a process for preparing same and pharmaceutical compositions
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
EP0101381A1 (fr) * 1982-08-16 1984-02-22 Sanofi S.A. Trifluorométhylphényltétrahydropyridines à activité anorexigène, un procédé de préparation et compositions pharmaceutiques
EP0372776A3 (en) * 1988-12-02 1991-10-23 Pfizer Inc. Arylpiperidine derivatives
WO1991008200A1 (en) * 1989-12-01 1991-06-13 Richter Gedeon Vegyészeti Gyár Rt. Novel tetrahydropyridine derivatives, a process for their preparation and pharmaceutical compositions containing such compounds as active agents
JP2002526493A (ja) * 1998-09-23 2002-08-20 ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・（エス．セー．エール．アー．エス） 新規なアミジン誘導体、その製造方法、その医薬としての使用及びこれを含有する医薬組成物

Also Published As

Publication number Publication date
NL6501492A (enExample) 1965-06-25
US3209006A (en) 1965-09-28
FR1421208A (enExample) 1965-12-17
CH404664A (fr) 1965-12-31

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