GB9313913D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
GB9313913D0
GB9313913D0 GB939313913A GB9313913A GB9313913D0 GB 9313913 D0 GB9313913 D0 GB 9313913D0 GB 939313913 A GB939313913 A GB 939313913A GB 9313913 A GB9313913 A GB 9313913A GB 9313913 D0 GB9313913 D0 GB 9313913D0
Authority
GB
United Kingdom
Prior art keywords
novel compounds
novel
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB939313913A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Priority to GB939313913A priority Critical patent/GB9313913D0/en
Publication of GB9313913D0 publication Critical patent/GB9313913D0/en
Priority to AT94921638T priority patent/ATE149163T1/de
Priority to CA002166624A priority patent/CA2166624A1/en
Priority to DE69401823T priority patent/DE69401823T2/de
Priority to PCT/EP1994/002148 priority patent/WO1995001976A1/en
Priority to AU72283/94A priority patent/AU7228394A/en
Priority to JP7503812A priority patent/JPH08512299A/ja
Priority to EP94921638A priority patent/EP0707581B1/en
Priority to CN94193185A priority patent/CN1129937A/zh
Priority to MA23564A priority patent/MA23254A1/fr
Priority to IL11020494A priority patent/IL110204A0/xx
Priority to ZA944807A priority patent/ZA944807B/xx
Priority to APAP/P/1994/000653A priority patent/AP463A/en
Priority to TW083106150A priority patent/TW297023B/zh
Priority to US08/717,957 priority patent/US5834494A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Eyeglasses (AREA)
GB939313913A 1993-07-06 1993-07-06 Novel compounds Pending GB9313913D0 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GB939313913A GB9313913D0 (en) 1993-07-06 1993-07-06 Novel compounds
CA002166624A CA2166624A1 (en) 1993-07-06 1994-06-30 Indoline derivatives as 5ht2c antagonists
JP7503812A JPH08512299A (ja) 1993-07-06 1994-06-30 ５ｈｔ▲下２ｃ▼アンタゴニストとしてのインドリン誘導体
CN94193185A CN1129937A (zh) 1993-07-06 1994-06-30 作为5ht2c拮抗剂的二氢吲哚衍生物
DE69401823T DE69401823T2 (de) 1993-07-06 1994-06-30 Indolin derivate als 5ht2c antagonisten
PCT/EP1994/002148 WO1995001976A1 (en) 1993-07-06 1994-06-30 Indoline derivatives as 5ht2c antagonists
AU72283/94A AU7228394A (en) 1993-07-06 1994-06-30 Indoline derivatives as 5HT2C antagonists
AT94921638T ATE149163T1 (de) 1993-07-06 1994-06-30 Indolin derivate als 5ht2c antagonisten
EP94921638A EP0707581B1 (en) 1993-07-06 1994-06-30 Indoline derivatives as 5ht2c antagonists
MA23564A MA23254A1 (fr) 1993-07-06 1994-07-04 Procede de preparation de nouveaux composes
APAP/P/1994/000653A AP463A (en) 1993-07-06 1994-07-04 "Indoline derivatives as 5HT2c antagonist".
IL11020494A IL110204A0 (en) 1993-07-06 1994-07-04 Novel indolene derivatives, processes for their preparation and their use for the treatment of cns disorders
ZA944807A ZA944807B (en) 1993-07-06 1994-07-04 Novel indoline derivatives processes for their preparation and their use as cns agents
TW083106150A TW297023B (https=) 1993-07-06 1994-07-05
US08/717,957 US5834494A (en) 1993-07-06 1996-09-23 Pyridylcarbamoyl Indolines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939313913A GB9313913D0 (en) 1993-07-06 1993-07-06 Novel compounds

Publications (1)

Publication Number Publication Date
GB9313913D0 true GB9313913D0 (en) 1993-08-18

Family

ID=10738344

Family Applications (1)

Application Number Title Priority Date Filing Date
GB939313913A Pending GB9313913D0 (en) 1993-07-06 1993-07-06 Novel compounds

Country Status (15)

Country Link
US (1) US5834494A (https=)
EP (1) EP0707581B1 (https=)
JP (1) JPH08512299A (https=)
CN (1) CN1129937A (https=)
AP (1) AP463A (https=)
AT (1) ATE149163T1 (https=)
AU (1) AU7228394A (https=)
CA (1) CA2166624A1 (https=)
DE (1) DE69401823T2 (https=)
GB (1) GB9313913D0 (https=)
IL (1) IL110204A0 (https=)
MA (1) MA23254A1 (https=)
TW (1) TW297023B (https=)
WO (1) WO1995001976A1 (https=)
ZA (1) ZA944807B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618824A (en) * 1994-03-09 1997-04-08 Merrell Pharmaceuticals Inc. Treatment of obsessive-compulsive disorders with 5-HT2 antagonists
GB9414139D0 (en) * 1994-07-13 1994-08-31 Smithkline Beecham Plc Novel compounds
GB9420521D0 (en) * 1994-10-12 1994-11-30 Smithkline Beecham Plc Novel compounds
RO115522B1 (ro) * 1995-02-02 2000-03-30 Smithkline Beecham P.L.C. Derivaţi de indolină, procedee pentru prepararea acestora, compoziţii farmaceutice care îi conţin şi metodă de tratament
US5972937A (en) * 1995-02-02 1999-10-26 Smithkline Beecham P.L.C. Heterocyclic compounds possessing 5HT2C receptor antagonist activity
GB9517559D0 (en) * 1995-08-26 1995-10-25 Smithkline Beecham Plc Novel compounds
AU2759597A (en) * 1996-05-16 1997-12-05 Allelix Biopharmaceuticals Inc. Thiophene- and furan-tryptamine derivatives
GB9612883D0 (en) 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
GB9612885D0 (en) 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU6123699A (en) * 1998-10-16 2000-05-08 Takeda Chemical Industries Ltd. Nitrogenous fused heterocycle compounds, process for the preparation thereof andagents containing the same
US6453357B1 (en) 1999-01-07 2002-09-17 Cisco Technology, Inc. Method and system for processing fragments and their out-of-order delivery during address translation
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
ES2252004T3 (es) * 1999-05-21 2006-05-16 Biovitrum Ab Nuevos compuestos, su uso y preparacion.
UA77650C2 (en) 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
FR2810979B1 (fr) * 2000-06-29 2002-08-23 Adir Nouveaux derives de diphenyluree, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
GB0019950D0 (en) * 2000-08-12 2000-09-27 Smithkline Beecham Plc Compounds
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
ATE241155T1 (de) * 2001-07-09 2003-06-15 Cit Alcatel Verbinder für optische fasern
US6861440B2 (en) 2001-10-26 2005-03-01 Hoffmann-La Roche Inc. DPP IV inhibitors
FR2837823B1 (fr) * 2002-03-27 2005-04-08 Servier Lab Nouveaux derives d'indoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN100484933C (zh) 2002-06-19 2009-05-06 比奥维特罗姆股份公开公司 新的吡嗪化合物及其在制备用于治疗与5-羟色胺相关的疾病的药物中的用途
RU2339636C2 (ru) 2003-06-20 2008-11-27 Ф.Хоффманн-Ля Рош Аг Гексагидропиридоизохинолины в качестве ингибиторов дипептидилпептидазы iv (dpp-iv)
ES2355105T3 (es) 2003-06-20 2011-03-22 F. Hoffmann-La Roche Ag Pirido(2,1-a)isoquinolina como inhibidores de la dpp-iv.
ATE521588T1 (de) * 2005-09-13 2011-09-15 Bayer Cropscience Ag Phenyloxy-substituierte phenylamidin-derivate als pestizide
US8293101B2 (en) 2009-03-13 2012-10-23 Terrasep, Llc Methods and apparatus for centrifugal liquid chromatography
CN106278987A (zh) * 2016-08-16 2017-01-04 都创(上海)医药科技有限公司 吲哚啉类化合物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428881A (en) * 1977-12-23 1984-01-31 Gulf Oil Corporation Control of unwanted vegetation with N-carbamylindolines
KR930702334A (ko) * 1990-09-13 1993-09-08 데이비드 로버트 5 하이드록시트립타민 수용체 길항제로서의 인돌우레아
AU4704693A (en) * 1992-08-20 1994-03-15 Smithkline Beecham Plc Condensed indole derivatives as 5HT-2C and 5HT-2B antagonists

Also Published As

Publication number Publication date
DE69401823T2 (de) 1997-08-28
CA2166624A1 (en) 1995-01-19
EP0707581B1 (en) 1997-02-26
MA23254A1 (fr) 1995-04-01
ZA944807B (en) 1996-01-04
EP0707581A1 (en) 1996-04-24
TW297023B (https=) 1997-02-01
AP463A (en) 1996-02-19
IL110204A0 (en) 1995-01-24
US5834494A (en) 1998-11-10
DE69401823D1 (de) 1997-04-03
JPH08512299A (ja) 1996-12-24
WO1995001976A1 (en) 1995-01-19
ATE149163T1 (de) 1997-03-15
AP9400653A0 (en) 1994-07-31
CN1129937A (zh) 1996-08-28
AU7228394A (en) 1995-02-06

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