GB920914A - New carbonyl compounds and their precursors and the production thereof - Google Patents

New carbonyl compounds and their precursors and the production thereof

Info

Publication number
GB920914A
GB920914A GB943058A GB943058A GB920914A GB 920914 A GB920914 A GB 920914A GB 943058 A GB943058 A GB 943058A GB 943058 A GB943058 A GB 943058A GB 920914 A GB920914 A GB 920914A
Authority
GB
United Kingdom
Prior art keywords
alkyl
formula
acid
carbonyl group
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB943058A
Inventor
Basil Charles Leicester Weedon
Charles Kenneth Warren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Development Corp UK
Original Assignee
National Research Development Corp UK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Development Corp UK filed Critical National Research Development Corp UK
Priority to GB943058A priority Critical patent/GB920914A/en
Priority to CH7119659A priority patent/CH382723A/en
Priority to BE577038A priority patent/BE577038A/en
Publication of GB920914A publication Critical patent/GB920914A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/12—Ketones containing more than one keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of formula <FORM:0920914/IV(a)/1> where Q is a carbonyl, hydroxymethylene, acyloxymethylene or ketalised (including cyclically ketalised) carbonyl group, R is alkyl, R5 is -OH, -OR6 or (except when Q is a carbonyl group) -R6, R6 being alkyl, R1 and R2 are alkyl and n is 1 or 2. Compounds of formula I in which R5 is alkyl may be prepared by reacting an acid <FORM:0920914/IV(a)/2> or a halide thereof with a metal alkyl. An acid of formula II may be obtained by hydrolysis of an ester of formula I where R5 = -OR6. A carbonyl group Q of such an ester may be ketalised with a mono- or di-hydric alcohol or a cyclic ketalising agent, e.g. 2ethylenedioxybutane, in the presence of ptoluenesulphonic acid, or may be hydrogenated to a hydroxymethylene group which may then be acylated. A keto ester of formula I wherein Q is carbonyl and R5 = -OR6 may be obtained by reacting an acid halide <FORM:0920914/IV(a)/3> where X is halogen with a metal alkyl. The acid halide III may be obtained by thionyl chloride on a monoester <FORM:0920914/IV(a)/4> obtainable by partial hydrolysis, e.g. with alcoholic KOH at normal temperatures, of the diester. The semicarbazone of methyl 2,2-dimethyl5-ketoheptanoate is prepared in an example. The Provisional Specification omits the limitation that R5 is not alkyl when Q is a carbonyl group in compounds of formula I.
GB943058A 1958-03-24 1958-03-24 New carbonyl compounds and their precursors and the production thereof Expired GB920914A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB943058A GB920914A (en) 1958-03-24 1958-03-24 New carbonyl compounds and their precursors and the production thereof
CH7119659A CH382723A (en) 1958-03-24 1959-03-24 Process for preparing carbonyl compounds
BE577038A BE577038A (en) 1958-03-24 1959-03-24 Carotenoid compounds, intermediates therefor and methods of preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB943058A GB920914A (en) 1958-03-24 1958-03-24 New carbonyl compounds and their precursors and the production thereof

Publications (1)

Publication Number Publication Date
GB920914A true GB920914A (en) 1963-03-13

Family

ID=9871818

Family Applications (1)

Application Number Title Priority Date Filing Date
GB943058A Expired GB920914A (en) 1958-03-24 1958-03-24 New carbonyl compounds and their precursors and the production thereof

Country Status (2)

Country Link
CH (1) CH382723A (en)
GB (1) GB920914A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0057731A1 (en) * 1980-07-11 1982-08-18 Syva Company Valproate derivatives and their conjugates to antigenic materials, antibodies thereto and method for the determination of valproate in physiological fluids
EP0247653A2 (en) * 1986-05-27 1987-12-02 EURON S.p.A. New compounds useful as detergent additives for lubricants and lubricating compositions

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0057731A1 (en) * 1980-07-11 1982-08-18 Syva Company Valproate derivatives and their conjugates to antigenic materials, antibodies thereto and method for the determination of valproate in physiological fluids
EP0247653A2 (en) * 1986-05-27 1987-12-02 EURON S.p.A. New compounds useful as detergent additives for lubricants and lubricating compositions
EP0247653A3 (en) * 1986-05-27 1989-05-17 Euron S.P.A. New compounds useful as detergent additives for lubricants and lubricating compositions

Also Published As

Publication number Publication date
CH382723A (en) 1964-10-15

Similar Documents

Publication Publication Date Title
CH361279A (en) Process for the preparation of cyclic phosphoric ester amides
ES360963A1 (en) Procedure for the obtaining of 3,4-hydroxyphenylalkanolamines. (Machine-translation by Google Translate, not legally binding)
CH420028A (en) Process for the production of sharp-edged metal objects and injection needle produced by the process
GB920914A (en) New carbonyl compounds and their precursors and the production thereof
GB996495A (en) Process for the production of pyrocarbonic acid esters
ES377283A1 (en) Process for the manufacture of cycloalkenones
GB842725A (en) Methods of preparing diketodicarboxylic acid esters, and diketodicarboxylic acid esters when prepared by said methods
GB1006152A (en) Method for producing dextro-trans-pyrethric acid
CH427773A (en) Process for the preparation of N-substituted 3-alkoxy-4-carbamido-methoxy-phenylacetic acid alkyl esters
GB977227A (en) Acyl-propiolic acid esters and process for their manufacture
AT202282B (en) Process for the preparation of the new morphine-bis-nicotinic acid ester
ES345183A1 (en) Glycyrrhetinic acid derivatives
ES321470A1 (en) Improvement for the obtaining of phosphoric esters with insecticide properties. (Machine-translation by Google Translate, not legally binding)
GB1107036A (en) Esters of dibenzocycloheptenyl-carboxylic acids
GB1177750A (en) Novel Gona-4,9,11-Trienes, Processes for their Preparation, and Pharmaceutical Compositions Incorporating them
GB879052A (en) Improvements in and relating to the production of acrylic acid esters
GB981460A (en) Hydrazine derivatives and process for making them
GB740959A (en) Manufacture of esters suitable for therapeutic application
ES334803A1 (en) A procedure for the preparation of 3-oxo 13 beta-r 17 beta-ox 2-oxa 4,9,11-gonatrienes. (Machine-translation by Google Translate, not legally binding)
GB795454A (en) Steroid compounds
ES275383A1 (en) Procedure for the obtaining of esters of acid o, O-dialquilditiofosforilacºtico (Machine-translation by Google Translate, not legally binding)
ES303113A1 (en) Procedure for preparing steroid ketones and their derivatives. (Machine-translation by Google Translate, not legally binding)
ES239816A1 (en) Procedure for obtaining hyponitar acid esters (Machine-translation by Google Translate, not legally binding)
ES369279A1 (en) Procedure for the production of new n, n&#39;-dimethyl-bisamidrazones of oxalic acid. (Machine-translation by Google Translate, not legally binding)
GB855430A (en) Certain esters of amino alcohols