GB920421A - New dexamethasone ester and process for its manufacture - Google Patents
New dexamethasone ester and process for its manufactureInfo
- Publication number
- GB920421A GB920421A GB22987/59A GB2298759A GB920421A GB 920421 A GB920421 A GB 920421A GB 22987/59 A GB22987/59 A GB 22987/59A GB 2298759 A GB2298759 A GB 2298759A GB 920421 A GB920421 A GB 920421A
- Authority
- GB
- United Kingdom
- Prior art keywords
- 11beta
- triol
- dione
- methyl
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960003957 dexamethasone Drugs 0.000 title 1
- -1 dexamethasone ester Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- JVSFQJZRHXAUGT-UHFFFAOYSA-N 2,2-dimethylpropanoyl chloride Chemical compound CC(C)(C)C(Cl)=O JVSFQJZRHXAUGT-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008298 dragée Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6138258 | 1958-07-04 | ||
| CH6771058A CH382735A (de) | 1958-12-24 | 1958-12-24 | Verfahren zur Herstellung von 16a-Methyl-17a-hydroxyverbindungen der Allopregnanreihe |
| CH7386859A CH394194A (de) | 1959-06-02 | 1959-06-02 | Verfahren zur Herstellung eines neuen Dexamethason-Esters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB920421A true GB920421A (en) | 1963-03-06 |
Family
ID=27178493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB22987/59A Expired GB920421A (en) | 1958-07-04 | 1959-07-03 | New dexamethasone ester and process for its manufacture |
Country Status (4)
| Country | Link |
|---|---|
| ES (1) | ES250438A1 (enrdf_load_stackoverflow) |
| FR (1) | FR406M (enrdf_load_stackoverflow) |
| GB (1) | GB920421A (enrdf_load_stackoverflow) |
| SE (1) | SE220496C1 (enrdf_load_stackoverflow) |
-
1959
- 1959-06-30 ES ES0250438A patent/ES250438A1/es not_active Expired
- 1959-07-02 SE SE626259A patent/SE220496C1/sv unknown
- 1959-07-03 GB GB22987/59A patent/GB920421A/en not_active Expired
-
1960
- 1960-08-30 FR FR837106A patent/FR406M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SE220496C1 (enrdf_load_stackoverflow) | 1968-05-14 |
| ES250438A1 (es) | 1960-03-01 |
| FR406M (enrdf_load_stackoverflow) | 1961-04-10 |
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