GB9114846D0 - Amidated fibrinolytic enzymes and their precursors,and processes for their preparation - Google Patents

Amidated fibrinolytic enzymes and their precursors,and processes for their preparation

Info

Publication number
GB9114846D0
GB9114846D0 GB919114846A GB9114846A GB9114846D0 GB 9114846 D0 GB9114846 D0 GB 9114846D0 GB 919114846 A GB919114846 A GB 919114846A GB 9114846 A GB9114846 A GB 9114846A GB 9114846 D0 GB9114846 D0 GB 9114846D0
Authority
GB
United Kingdom
Prior art keywords
amidated
precursors
processes
preparation
fibrinolytic enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB919114846A
Other versions
GB2246133A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of GB9114846D0 publication Critical patent/GB9114846D0/en
Publication of GB2246133A publication Critical patent/GB2246133A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB9114846A 1990-07-12 1991-07-10 Amidated human pro-urokinase enzymes and their precursors Withdrawn GB2246133A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909015369A GB9015369D0 (en) 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation

Publications (2)

Publication Number Publication Date
GB9114846D0 true GB9114846D0 (en) 1991-08-28
GB2246133A GB2246133A (en) 1992-01-22

Family

ID=10679005

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909015369A Pending GB9015369D0 (en) 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation
GB9114846A Withdrawn GB2246133A (en) 1990-07-12 1991-07-10 Amidated human pro-urokinase enzymes and their precursors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909015369A Pending GB9015369D0 (en) 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation

Country Status (4)

Country Link
JP (1) JPH04252185A (en)
DE (1) DE4122688A1 (en)
GB (2) GB9015369D0 (en)
IT (1) IT1250653B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656456A (en) * 1992-07-13 1997-08-12 Bionebraska, Inc. Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof
DE69332377T2 (en) * 1992-07-13 2003-07-03 Bionebraska, Inc. METHOD FOR MODIFYING RECOMBINANT POLYPEPTIDES
WO1996017941A2 (en) * 1994-12-07 1996-06-13 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
CA2426115A1 (en) * 2003-04-18 2004-10-18 Victor Gurewich Methods, devices, and compositions for lysis of occlusive blood clots while sparing wound sealing clots

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8523156D0 (en) * 1985-09-19 1985-10-23 Celltech Ltd Polypeptide production
GB2220938B (en) * 1988-07-20 1992-01-29 Erba Carlo Spa Use of pam enzyme in solid phase peptide synthesis

Also Published As

Publication number Publication date
GB9015369D0 (en) 1990-08-29
GB2246133A (en) 1992-01-22
ITMI911877A0 (en) 1991-07-08
DE4122688A1 (en) 1992-01-16
JPH04252185A (en) 1992-09-08
ITMI911877A1 (en) 1993-01-08
IT1250653B (en) 1995-04-21

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)