GB9015369D0 - Amidated fibrinolytic enzymes and their precursors,and processes for their preparation - Google Patents

Amidated fibrinolytic enzymes and their precursors,and processes for their preparation

Info

Publication number
GB9015369D0
GB9015369D0 GB909015369A GB9015369A GB9015369D0 GB 9015369 D0 GB9015369 D0 GB 9015369D0 GB 909015369 A GB909015369 A GB 909015369A GB 9015369 A GB9015369 A GB 9015369A GB 9015369 D0 GB9015369 D0 GB 9015369D0
Authority
GB
United Kingdom
Prior art keywords
amidated
precursors
processes
preparation
fibrinolytic enzymes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB909015369A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Priority to GB909015369A priority Critical patent/GB9015369D0/en
Publication of GB9015369D0 publication Critical patent/GB9015369D0/en
Priority to ITMI911877A priority patent/IT1250653B/en
Priority to DE4122688A priority patent/DE4122688A1/en
Priority to GB9114846A priority patent/GB2246133A/en
Priority to JP3196960A priority patent/JPH04252185A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6462Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21073Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB909015369A 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation Pending GB9015369D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB909015369A GB9015369D0 (en) 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation
ITMI911877A IT1250653B (en) 1990-07-12 1991-07-08 FIBRINOLYTIC ENZYMES AMID AND THEIR PRECURSORS, AND PROCESSES FOR THEIR PREPARATION.
DE4122688A DE4122688A1 (en) 1990-07-12 1991-07-09 AMIDATED FIBRINOLYTIC ENZYME AND ITS PRECURSORS AND METHOD FOR THE PRODUCTION THEREOF
GB9114846A GB2246133A (en) 1990-07-12 1991-07-10 Amidated human pro-urokinase enzymes and their precursors
JP3196960A JPH04252185A (en) 1990-07-12 1991-07-11 Amidated cellulose dissolving enzyme, its precursor and production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909015369A GB9015369D0 (en) 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation

Publications (1)

Publication Number Publication Date
GB9015369D0 true GB9015369D0 (en) 1990-08-29

Family

ID=10679005

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909015369A Pending GB9015369D0 (en) 1990-07-12 1990-07-12 Amidated fibrinolytic enzymes and their precursors,and processes for their preparation
GB9114846A Withdrawn GB2246133A (en) 1990-07-12 1991-07-10 Amidated human pro-urokinase enzymes and their precursors

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB9114846A Withdrawn GB2246133A (en) 1990-07-12 1991-07-10 Amidated human pro-urokinase enzymes and their precursors

Country Status (4)

Country Link
JP (1) JPH04252185A (en)
DE (1) DE4122688A1 (en)
GB (2) GB9015369D0 (en)
IT (1) IT1250653B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656456A (en) * 1992-07-13 1997-08-12 Bionebraska, Inc. Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof
NZ255041A (en) * 1992-07-13 1996-11-26 Bionebraska Inc Preparation of a recombinant single copy polypeptide or portion thereof modified with a terminal alpha amino carbon reactive group and reactive side chain groups involving biologically added protective groups
WO1996017941A2 (en) * 1994-12-07 1996-06-13 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
CA2426115A1 (en) * 2003-04-18 2004-10-18 Victor Gurewich Methods, devices, and compositions for lysis of occlusive blood clots while sparing wound sealing clots

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8523156D0 (en) * 1985-09-19 1985-10-23 Celltech Ltd Polypeptide production
GB2220938B (en) * 1988-07-20 1992-01-29 Erba Carlo Spa Use of pam enzyme in solid phase peptide synthesis

Also Published As

Publication number Publication date
JPH04252185A (en) 1992-09-08
ITMI911877A0 (en) 1991-07-08
GB9114846D0 (en) 1991-08-28
GB2246133A (en) 1992-01-22
ITMI911877A1 (en) 1993-01-08
IT1250653B (en) 1995-04-21
DE4122688A1 (en) 1992-01-16

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