GB889225A - - Google Patents

Info

Publication number
GB889225A
GB889225A GB889225DA GB889225A GB 889225 A GB889225 A GB 889225A GB 889225D A GB889225D A GB 889225DA GB 889225 A GB889225 A GB 889225A
Authority
GB
United Kingdom
Prior art keywords
anaesthetic
local anaesthetic
bidocaine
bestacaine
carbocaine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication of GB889225A publication Critical patent/GB889225A/en
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

889,225. Surface anaesthetics. BOFORS, A.B. June 29, 1960 [July 1, 1959], No. 22781/60. Class 81 (1). A surface anaesthetic of low toxicity comprises, in admixture, a compound or mixture of compounds having local anaesthetic activity of the general formula wherein R represents an alkyl, aryl or alkylaryl groups having from 6 to 20 carbon atoms and n has a value lying between 4 and 16 and an injectable local anaesthetic, e.g. procaine, tetracaine, bestacaine, bidocaine or carbocaine. For application the active materials may be dissolved in a suitable solvent e.g. water or mixed with an appropriate carrier to form an ointment, gel or solution tablet.
GB889225D 1959-07-01 Active GB889225A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE6204/59A SE306139B (en) 1959-07-01 1959-07-01

Publications (1)

Publication Number Publication Date
GB889225A true GB889225A (en)

Family

ID=20268139

Family Applications (1)

Application Number Title Priority Date Filing Date
GB889225D Active GB889225A (en) 1959-07-01

Country Status (5)

Country Link
US (1) US3038835A (en)
DE (1) DE1299796B (en)
FR (1) FR13M (en)
GB (1) GB889225A (en)
SE (1) SE306139B (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0024382A1 (en) * 1979-07-10 1981-03-04 af Ekenstam, Bo Piperidine derivatives, their preparation and pharmaceutical compositions containing them
EP0031603A1 (en) * 1979-12-31 1981-07-08 American Cyanamid Company Pharmaceutical composition of matter
US4529601A (en) * 1977-12-01 1985-07-16 Astra Lakemedel Aktiebolag Local anesthetic mixture for topical application and method for obtaining local anesthesia
WO1995012576A1 (en) * 1993-11-04 1995-05-11 Instituto De Investigacion Y Desarrollo Quimico Biologico, S.A. New cyclopropyl derivatives, preparation method thereof and applications
US5715572A (en) * 1994-01-04 1998-02-10 Amiram Steinberg & Dalia Lapidot Hinge
US5776859A (en) * 1995-11-15 1998-07-07 Nickel; Alfred A. Sodium channel active novel compounds and related processes and bioassay techniques
US5834490A (en) * 1993-11-04 1998-11-10 Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. Cyclopropyl derivatives, preparation method there-of and applications

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425559A (en) * 1972-09-01 1976-02-18 Wyeth John & Brother Ltd Pyridine tetrahydropyridine and piperidine derivatives
US4344965A (en) * 1978-10-13 1982-08-17 Raymond Stone Anesthetic compositions containing benzocaine
FR2528834B1 (en) * 1982-06-16 1986-03-07 Sanofi Sa AMMONIUM SALTS QUATERNARY OF CYCLIC AMINES DISUBSTITUTED IN A AND A 'BY PHENYLCARBAMOYLE GROUPS POTENTIALLY SUBSTITUTED ON PHENYL, AND ANTIARRHYTHMIC ACTS COMPRISING SAID SALTS
JP2000500502A (en) * 1995-11-22 2000-01-18 メルク エンド カンパニー インコーポレーテッド Farnesyl-protein transferase inhibitor
GB9604311D0 (en) * 1996-02-29 1996-05-01 Merck & Co Inc Inhibitors of farnesyl-protein transferase
US6127366A (en) * 1995-11-22 2000-10-03 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB805523A (en) * 1955-08-08 1958-12-10 Cook Waite Lab Inc Local anesthetic composition and preparation thereof
GB799780A (en) * 1956-02-22 1958-08-13 Bofors Ab New n-alkyl-alkyl-piperidine-ª‡-monocarboxylic acid amides and n-alkyl-alkyl-pyrrolidine-ª‡-monocarboxylic acid amides
GB799779A (en) * 1956-02-22 1958-08-13 Bofors Ab Method of producing n-alkyl-alkyl-piperidine monocarboxylic acid amides and n-alkyl-alkyl-pyrrolidine monocarboxylic acid amides

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4529601A (en) * 1977-12-01 1985-07-16 Astra Lakemedel Aktiebolag Local anesthetic mixture for topical application and method for obtaining local anesthesia
US4562060A (en) * 1977-12-01 1985-12-31 Astra Lakemedel Aktiebolag Local anesthetic mixture for topical application, process for its preparation, as well as method for obtaining local anesthesia
EP0024382A1 (en) * 1979-07-10 1981-03-04 af Ekenstam, Bo Piperidine derivatives, their preparation and pharmaceutical compositions containing them
EP0031603A1 (en) * 1979-12-31 1981-07-08 American Cyanamid Company Pharmaceutical composition of matter
WO1995012576A1 (en) * 1993-11-04 1995-05-11 Instituto De Investigacion Y Desarrollo Quimico Biologico, S.A. New cyclopropyl derivatives, preparation method thereof and applications
ES2082703A1 (en) * 1993-11-04 1996-03-16 Inst Investigacion Desarrollo New cyclopropyl derivatives, preparation method thereof and applications.
AU693123B2 (en) * 1993-11-04 1998-06-25 Instituto De Investigacion Y Desarrollo Quimico Biologico, S.A. New cyclopropyl derivatives, preparation method thereof and applications
US5834490A (en) * 1993-11-04 1998-11-10 Instituto De Investigacion Y Desarrolo Quimico Biologico, S.A. Cyclopropyl derivatives, preparation method there-of and applications
US5715572A (en) * 1994-01-04 1998-02-10 Amiram Steinberg & Dalia Lapidot Hinge
US5776859A (en) * 1995-11-15 1998-07-07 Nickel; Alfred A. Sodium channel active novel compounds and related processes and bioassay techniques

Also Published As

Publication number Publication date
FR13M (en) 1960-11-28
US3038835A (en) 1962-06-12
DE1299796B (en) 1969-07-24
SE306139B (en) 1968-11-18

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