GB886619A - 6-methyl-16-methylene steroids - Google Patents
6-methyl-16-methylene steroidsInfo
- Publication number
- GB886619A GB886619A GB2950859A GB2950859A GB886619A GB 886619 A GB886619 A GB 886619A GB 2950859 A GB2950859 A GB 2950859A GB 2950859 A GB2950859 A GB 2950859A GB 886619 A GB886619 A GB 886619A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxy
- acyloxy
- agent
- give
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AZQWKYJCGOJGHM-UHFFFAOYSA-N 1,4-benzoquinone Chemical compound O=C1C=CC(=O)C=C1 AZQWKYJCGOJGHM-UHFFFAOYSA-N 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- -1 hydrogen ions Chemical class 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 238000006036 Oppenauer oxidation reaction Methods 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- SDTMFDGELKWGFT-UHFFFAOYSA-N 2-methylpropan-2-olate Chemical compound CC(C)(C)[O-] SDTMFDGELKWGFT-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000012345 acetylating agent Substances 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 239000004411 aluminium Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910000042 hydrogen bromide Inorganic materials 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000012454 non-polar solvent Substances 0.000 abstract 1
- KJIFKLIQANRMOU-UHFFFAOYSA-N oxidanium;4-methylbenzenesulfonate Chemical compound O.CC1=CC=C(S(O)(=O)=O)C=C1 KJIFKLIQANRMOU-UHFFFAOYSA-N 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- UGNWTBMOAKPKBL-UHFFFAOYSA-N tetrachloro-1,4-benzoquinone Chemical compound ClC1=C(Cl)C(=O)C(Cl)=C(Cl)C1=O UGNWTBMOAKPKBL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2950859A GB886619A (en) | 1959-08-28 | 1959-08-28 | 6-methyl-16-methylene steroids |
| GB2288961A GB886620A (en) | 1959-08-28 | 1959-08-28 | 6, 16-dimethyl steroids |
| DEB58298A DE1134987B (de) | 1959-08-28 | 1960-06-22 | Verfahren zur Herstellung von 17ª‡-Acyloxy-6-methyl-16-methylen-pregna-4, 6-dien-3, 20-dionen |
| FR1563602D FR1563602A (enrdf_load_stackoverflow) | 1959-08-28 | 1960-07-20 | |
| CH932260A CH394188A (de) | 1959-08-28 | 1960-08-17 | Verfahren zur Herstellung von Acyloxy-dien-dion-Steroiden |
| BE594445A BE594445A (fr) | 1959-08-28 | 1960-08-26 | Nouveaux stéroïdes. |
| US423579A US3332940A (en) | 1959-08-28 | 1965-01-05 | Process for the preparation of 17alpha-acyloxy-6-methyl-16-methylene-4, 6-pregnadiene-3, 20-diones and intermediates obtained therefrom |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2950859A GB886619A (en) | 1959-08-28 | 1959-08-28 | 6-methyl-16-methylene steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB886619A true GB886619A (en) | 1962-01-10 |
Family
ID=10292640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2950859A Expired GB886619A (en) | 1959-08-28 | 1959-08-28 | 6-methyl-16-methylene steroids |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE594445A (enrdf_load_stackoverflow) |
| CH (1) | CH394188A (enrdf_load_stackoverflow) |
| DE (1) | DE1134987B (enrdf_load_stackoverflow) |
| FR (1) | FR1563602A (enrdf_load_stackoverflow) |
| GB (1) | GB886619A (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346037A (en) | 1981-07-10 | 1982-08-24 | The Upjohn Company | Base catalyzed acylation with enol esters |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH236309A (de) * | 1940-02-20 | 1945-01-31 | Chem Ind Basel | Verfahren zur Darstellung eines ,ss; , -zweifach ungesättigten Ketons. |
-
1959
- 1959-08-28 GB GB2950859A patent/GB886619A/en not_active Expired
-
1960
- 1960-06-22 DE DEB58298A patent/DE1134987B/de active Pending
- 1960-07-20 FR FR1563602D patent/FR1563602A/fr not_active Expired
- 1960-08-17 CH CH932260A patent/CH394188A/de unknown
- 1960-08-26 BE BE594445A patent/BE594445A/fr unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346037A (en) | 1981-07-10 | 1982-08-24 | The Upjohn Company | Base catalyzed acylation with enol esters |
Also Published As
| Publication number | Publication date |
|---|---|
| BE594445A (fr) | 1961-02-27 |
| FR1563602A (enrdf_load_stackoverflow) | 1969-04-18 |
| CH394188A (de) | 1965-06-30 |
| DE1134987B (de) | 1962-08-23 |
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