GB883745A - Improvements in or relating to aminoalkylmorpholine derivatives - Google Patents
Improvements in or relating to aminoalkylmorpholine derivativesInfo
- Publication number
- GB883745A GB883745A GB15770/60A GB1577060A GB883745A GB 883745 A GB883745 A GB 883745A GB 15770/60 A GB15770/60 A GB 15770/60A GB 1577060 A GB1577060 A GB 1577060A GB 883745 A GB883745 A GB 883745A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- phenyl
- morpholine
- radical
- phenylmorpholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- -1 methoxyphenyl Chemical group 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QUWRNBZDJLHWAJ-UHFFFAOYSA-N 2,3-diphenyl-N-(1-phenylpropan-2-yl)morpholin-4-amine Chemical compound CC(CC1=CC=CC=C1)NN1C(C(OCC1)C1=CC=CC=C1)C1=CC=CC=C1 QUWRNBZDJLHWAJ-UHFFFAOYSA-N 0.000 abstract 1
- LROAJFXHXBZFQM-UHFFFAOYSA-N 2-(4-methoxyphenyl)-3-methyl-n-(1-phenylpropan-2-yl)morpholin-4-amine Chemical compound C1=CC(OC)=CC=C1C1C(C)N(NC(C)CC=2C=CC=CC=2)CCO1 LROAJFXHXBZFQM-UHFFFAOYSA-N 0.000 abstract 1
- XOBOGDAHNXZSME-UHFFFAOYSA-N 2-cyclohexyl-3-methyl-n-(1-phenylpropan-2-yl)morpholin-4-amine Chemical compound C1COC(C2CCCCC2)C(C)N1NC(C)CC1=CC=CC=C1 XOBOGDAHNXZSME-UHFFFAOYSA-N 0.000 abstract 1
- YBMCKFJKTOHPMA-UHFFFAOYSA-N 2-phenyl-N-(1-phenylpropan-2-yl)morpholin-4-amine Chemical compound CC(CC1=CC=CC=C1)NN1CC(OCC1)C1=CC=CC=C1 YBMCKFJKTOHPMA-UHFFFAOYSA-N 0.000 abstract 1
- KBRSLPYGHGQKNS-UHFFFAOYSA-N 3-methyl-2-phenyl-n-(1-phenylpropan-2-yl)morpholin-4-amine Chemical compound C1COC(C=2C=CC=CC=2)C(C)N1NC(C)CC1=CC=CC=C1 KBRSLPYGHGQKNS-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- OCPATNNRIATJOB-UHFFFAOYSA-N N-[1-(3,4-dimethoxyphenyl)propan-2-yl]-3-methyl-2-phenylmorpholin-4-amine Chemical compound CC1N(CCOC1C1=CC=CC=C1)NC(CC1=CC(=C(C=C1)OC)OC)C OCPATNNRIATJOB-UHFFFAOYSA-N 0.000 abstract 1
- BQOWUDKEXDCGQS-UHFFFAOYSA-N [CH]1CCCC1 Chemical group [CH]1CCCC1 BQOWUDKEXDCGQS-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000005805 dimethoxy phenyl group Chemical group 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical group [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 125000001041 indolyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004351 phenylcyclohexyl group Chemical group C1(=CC=CC=C1)C1(CCCCC1)* 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- 238000006268 reductive amination reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81099759A | 1959-05-05 | 1959-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB883745A true GB883745A (en) | 1961-12-06 |
Family
ID=25205253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB15770/60A Expired GB883745A (en) | 1959-05-05 | 1960-05-04 | Improvements in or relating to aminoalkylmorpholine derivatives |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE590488A (enrdf_load_stackoverflow) |
| CH (1) | CH390253A (enrdf_load_stackoverflow) |
| DE (1) | DE1179940B (enrdf_load_stackoverflow) |
| FR (1) | FR513M (enrdf_load_stackoverflow) |
| GB (1) | GB883745A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2656747C2 (de) * | 1976-12-15 | 1984-07-05 | Basf Ag, 6700 Ludwigshafen | Morpholinderivate |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2730526A (en) * | 1951-05-21 | 1956-01-10 | American Cyanamid Co | Preparation of 2-benzothiazolyl sulfene morpholide |
| DE1063601B (de) * | 1952-12-04 | 1959-08-20 | Lepetit Spa | Verfahren zur Herstellung von Schiffschen Basen aus gesaettigten N-heterocyclischen Verbindungen, die am ringstaendigen Stickstoffatom eine Aminogruppe tragen, und Nitro-acylthiophenen |
| GB763406A (en) * | 1954-10-01 | 1956-12-12 | Roche Products Ltd | Novel 6-aminomethyl-5-hydroxy-indane derivatives and a process for the manufacture thereof |
| GB762720A (en) * | 1954-10-08 | 1956-12-05 | Roche Products Ltd | Novel morpholinomethyl-phenyl derivatives and the manufacture thereof |
| US2868786A (en) * | 1954-12-27 | 1959-01-13 | Ravensberg G M B H | Esters of phenyl acetic acids and a process of making same |
| GB791416A (en) * | 1956-04-09 | 1958-03-05 | Albert Boehringer | Improvements in or relating to the production of substituted tetrahydrooxazines |
| US2832777A (en) * | 1956-11-26 | 1958-04-29 | Searle & Co | 2-aminophenyl-3-methylmorpholines |
-
1960
- 1960-05-03 DE DE1960S0068340 patent/DE1179940B/de active Pending
- 1960-05-04 BE BE590488A patent/BE590488A/fr unknown
- 1960-05-04 CH CH509760A patent/CH390253A/de unknown
- 1960-05-04 GB GB15770/60A patent/GB883745A/en not_active Expired
- 1960-08-30 FR FR837285A patent/FR513M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DE1179940B (de) | 1964-10-22 |
| BE590488A (fr) | 1960-11-21 |
| CH390253A (de) | 1965-04-15 |
| FR513M (enrdf_load_stackoverflow) | 1961-05-15 |
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