GB877318A - The manufacture of cytidines - Google Patents

The manufacture of cytidines

Info

Publication number
GB877318A
GB877318A GB17544/60A GB1754460A GB877318A GB 877318 A GB877318 A GB 877318A GB 17544/60 A GB17544/60 A GB 17544/60A GB 1754460 A GB1754460 A GB 1754460A GB 877318 A GB877318 A GB 877318A
Authority
GB
United Kingdom
Prior art keywords
fluoro
deoxy
dioxo
phenyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB17544/60A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB877318A publication Critical patent/GB877318A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/10—Mercury compounds
    • C07F3/103—Mercury compounds without C-Mercury linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB17544/60A 1959-06-03 1960-05-18 The manufacture of cytidines Expired GB877318A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US817736A US3040026A (en) 1959-06-03 1959-06-03 Processes and intermediates for deoxyfluorocytidine

Publications (1)

Publication Number Publication Date
GB877318A true GB877318A (en) 1961-09-13

Family

ID=25223771

Family Applications (1)

Application Number Title Priority Date Filing Date
GB17544/60A Expired GB877318A (en) 1959-06-03 1960-05-18 The manufacture of cytidines

Country Status (7)

Country Link
US (2) US3040026A (enExample)
BE (1) BE591486A (enExample)
CH (2) CH426841A (enExample)
DE (2) DE1745629B1 (enExample)
GB (1) GB877318A (enExample)
NL (1) NL299755A (enExample)
SE (2) SE309778B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1219938B (de) * 1962-05-01 1966-06-30 Hoffmann La Roche Verfahren zur Herstellung von 4-N-p-Toluoyl-5-fluor-2'-desoxycytidin
DE1264445B (de) * 1963-10-09 1968-03-28 Robugen Gmbh Verfahren zur Herstellung von 2, 6-Dichlor-5-fluorpyrimidin
US4703121A (en) * 1984-11-14 1987-10-27 Bayer Aktiengesellschaft Process for the preparation of 5-fluorocytosine

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3282919A (en) * 1964-02-06 1966-11-01 American Cyanamid Co Process for preparing orotidine
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same
US3309359A (en) * 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
DE2359536C2 (de) * 1972-12-08 1984-08-02 Takeda Chemical Industries, Ltd., Osaka 2,6-Diaminonebularinderivate
US4041037A (en) * 1975-06-10 1977-08-09 American Home Products Corporation Antitumor derivatives of periodate-oxidized cytidine
US4232154A (en) * 1977-12-13 1980-11-04 United States Of America Carbocyclic analogs of cytosine nucleosides exhibiting antiviral and antineoplasticactivity
US4177348A (en) * 1977-12-13 1979-12-04 United States Government Carbocyclic analogs of cytosine nucleosides
US5155221A (en) * 1992-03-06 1992-10-13 Dowelanco Process for the preparation of 2-alkylthio-4-hydrazino-5-fluoropyrimidines
CN106632080A (zh) * 2016-08-25 2017-05-10 宿迁市万和泰化工有限公司 一种氟胞嘧啶的生产工艺
CN106349169A (zh) * 2016-08-25 2017-01-25 宿迁市万和泰化工有限公司 一种适用于工业生产的氟胞嘧啶的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE870558C (de) * 1942-09-06 1953-03-16 Bayer Ag Verfahren zur Herstellung von 2-Aminopyrimidin
US2688019A (en) * 1951-08-25 1954-08-31 Burroughs Wellcome Co 6-aryl-2,4-diamino pyrimidines and process of preparing same
US2804459A (en) * 1955-02-23 1957-08-27 Pfizer & Co C Preparation of 4-aminouracil
US2892840A (en) * 1955-12-05 1959-06-30 Kay Fries Chemicals Inc Preparation of cytosine and intermediates
US2885396A (en) * 1957-03-21 1959-05-05 Heidelberger Charles N-glycosides of 5-fluorouracil
US2937171A (en) * 1958-06-13 1960-05-17 Du Pont Process for obtaining fluorinated organic compounds

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1219938B (de) * 1962-05-01 1966-06-30 Hoffmann La Roche Verfahren zur Herstellung von 4-N-p-Toluoyl-5-fluor-2'-desoxycytidin
DE1264445B (de) * 1963-10-09 1968-03-28 Robugen Gmbh Verfahren zur Herstellung von 2, 6-Dichlor-5-fluorpyrimidin
US4703121A (en) * 1984-11-14 1987-10-27 Bayer Aktiengesellschaft Process for the preparation of 5-fluorocytosine

Also Published As

Publication number Publication date
NL299755A (enExample)
CH408024A (de) 1966-02-28
SE320974B (enExample) 1970-02-23
DE1132926B (de) 1962-07-12
US3040026A (en) 1962-06-19
SE309778B (enExample) 1969-04-08
US3185690A (en) 1965-05-25
DE1745629B1 (de) 1970-07-23
CH426841A (de) 1966-12-31
BE591486A (fr) 1960-12-02

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