Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB18559/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co IncfiledCriticalMerck and Co Inc
Publication of GB876995ApublicationCriticalpatent/GB876995A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members
(AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
Benzothiadiazine - 1:1 - dioxides of the formula <FORM:0876995/IV (b)/1> wherein R1 is hydrogen, halogen (e.g. Br, Cl, F), C1-C5 alkyl, C1-C5 alkoxy or nitro, R2 is hydrogen or C1-C5 alkyl and R3 is hydrogen or C1-C5 alkyl are prepared by treating a disulphamoyl aniline of the formula <FORM:0876995/IV (b)/2> with an amide of the formula R3.CO.NR4R5, wherein R4 and R5 are hydrogen or C1-C5 alkyl groups, preferably in the presence of an acid catalyst at 150 DEG -200 DEG C. Specifications 826,921 and 826,923 are referred to.
GB18559/58A1957-06-171958-06-10Preparation of benzothiadiazine-1,1-dioxide derivatives
ExpiredGB876995A
(en)
Procedure for the preparation of chemical compounds 3-4-dihydro-1,2,4-benzotiadiazona-1,1-dioxide (Machine-translation by Google Translate, not legally binding)