GB872448A - 1-acyl-3 substituted azetidines - Google Patents

1-acyl-3 substituted azetidines

Info

Publication number
GB872448A
GB872448A GB42444/59A GB4244459A GB872448A GB 872448 A GB872448 A GB 872448A GB 42444/59 A GB42444/59 A GB 42444/59A GB 4244459 A GB4244459 A GB 4244459A GB 872448 A GB872448 A GB 872448A
Authority
GB
United Kingdom
Prior art keywords
acyl
alkyl
cycloalkyl
phenyl
substituted azetidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB42444/59A
Inventor
Emilio Testa
Luigi Fontanella
Giulio Maffii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit SpA filed Critical Lepetit SpA
Priority to GB42444/59A priority Critical patent/GB872448A/en
Publication of GB872448A publication Critical patent/GB872448A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention comprises compounds of the general formulae <FORM:0872448/IV (b)/1> wherein R1 represents hydrogen, a C1-8-alkyl, cycloalkyl, phenyl or phenylalkyl group and R2 and R3 represent C1-8 alkyl, cycloalkyl phenyl or phenylalkyl radicals, and the preparation thereof reacting an azetidine of the general formula <FORM:0872448/IV (b)/2> with an acylating agent of the class consisting of chlorides and anhydrides of a carboxylic acid R.3COOH. if desired in the presence of a tertiary amino base, at between 0 and 120 DEG C. Specification 829,633 also is referred to.
GB42444/59A 1958-12-23 1958-12-23 1-acyl-3 substituted azetidines Expired GB872448A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB42444/59A GB872448A (en) 1958-12-23 1958-12-23 1-acyl-3 substituted azetidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB42444/59A GB872448A (en) 1958-12-23 1958-12-23 1-acyl-3 substituted azetidines

Publications (1)

Publication Number Publication Date
GB872448A true GB872448A (en) 1961-07-12

Family

ID=10424446

Family Applications (1)

Application Number Title Priority Date Filing Date
GB42444/59A Expired GB872448A (en) 1958-12-23 1958-12-23 1-acyl-3 substituted azetidines

Country Status (1)

Country Link
GB (1) GB872448A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007038459A3 (en) * 2005-09-27 2007-07-12 Novartis Ag Carboxyamine compounds and their use in the treatment of hdac dependent diseases
WO2010149761A1 (en) * 2009-06-25 2010-12-29 Bioversys Gmbh Composition for treatment of tuberculosis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007038459A3 (en) * 2005-09-27 2007-07-12 Novartis Ag Carboxyamine compounds and their use in the treatment of hdac dependent diseases
JP2009510073A (en) * 2005-09-27 2009-03-12 ノバルティス アクチエンゲゼルシャフト Carboxyamine compounds and methods of use thereof
WO2010149761A1 (en) * 2009-06-25 2010-12-29 Bioversys Gmbh Composition for treatment of tuberculosis
CN102458393A (en) * 2009-06-25 2012-05-16 生物验证系统股份公司 Composition for treatment of tuberculosis
CN102458393B (en) * 2009-06-25 2014-08-20 生物验证系统股份公司 Composition for treatment of tuberculosis

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