GB869552A - New cyanopyrazoles - Google Patents

New cyanopyrazoles

Info

Publication number
GB869552A
GB869552A GB37829/58A GB3782958A GB869552A GB 869552 A GB869552 A GB 869552A GB 37829/58 A GB37829/58 A GB 37829/58A GB 3782958 A GB3782958 A GB 3782958A GB 869552 A GB869552 A GB 869552A
Authority
GB
United Kingdom
Prior art keywords
formula
nhr
talc
acetonitrile
starch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB37829/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Schweiz AG
Original Assignee
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba AG filed Critical Ciba AG
Publication of GB869552A publication Critical patent/GB869552A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

The invention comprises 3-amino-4-cyanopyrazoles of the formula: <FORM:0869552/IV (b)/1> where R represents an aliphatic or cycloaliphatic hydrocarbon radical containing at least 4 carbon atoms, and salts of such compounds with a large number of inorganic and organic acids, including ascorbic acid. The compounds are prepared by reacting a hydrazine of the formula H2N.NHR with a -cyanoa -formyl-acetonitrile or a reactive aldehyde derivative thereof, such as an a -alkoxymethylene-a -cyano-acetonitrile. Hydrazines of the formula H2N.NHR are prepared by reacting hydrazine with an appropriate ketone and hydrogenating the resulting hydrazone.ALSO:A pharmaceutical composition comprises a 3-amino-4-cyanopyrazole of the formula <FORM:0869552/VI/1> where R represents an aliphatic or cycloaliphatic hydrocarbon radical containing at least 4 carbon atoms, and/or a salt thereof with a physiologically-tolerated acid together with a pharmaceutical carrier suitable for enteral or parenteral administration, e.g. water, gelatine, lactose, petroleum jelly, starch, magnesium stearate, talc, starch, magnesium stearate, talc, vegetable oils, benzyl alcohols, gums, polyalkylene glycols, cholesterol and wetting or emulsifying agents.
GB37829/58A 1957-11-26 1958-11-24 New cyanopyrazoles Expired GB869552A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH869552X 1957-11-26

Publications (1)

Publication Number Publication Date
GB869552A true GB869552A (en) 1961-05-31

Family

ID=4543916

Family Applications (1)

Application Number Title Priority Date Filing Date
GB37829/58A Expired GB869552A (en) 1957-11-26 1958-11-24 New cyanopyrazoles

Country Status (1)

Country Link
GB (1) GB869552A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121092A (en) * 1962-01-29 1964-02-11 Abbott Lab Pyrazole derivative

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121092A (en) * 1962-01-29 1964-02-11 Abbott Lab Pyrazole derivative

Similar Documents

Publication Publication Date Title
AU529888B2 (en) Aqueous isocyanate emulsions and their use as binders in a process for the production of shaped articles
SE7604476L (en) PROCEDURE FOR PREPARING 1- (3,3,3-TRIARYLPROPYL) -4-PHENYL-4-PIPERIDINEMETHANOL COMPOUNDS
GB869552A (en) New cyanopyrazoles
ES414956A1 (en) Halogenated 4-(4&#39;-bisphenylyl)-butanols
ES388953A1 (en) 3- 3,4, - dichloro -6,- alkylphenyl - delta2 - pyrazoline deriva tives and a process for their manufacture
DE3165454D1 (en) N-sulfenylated biurets, process for their preparation, and their use as fungicides
GB791688A (en) Improvements in or relating to pyrazole derivatives
SE7611953L (en) PROCEDURE FOR PREPARING AROYL-PHENYL-NAFTALENDER DERIVATIVES USABLE AS ANTIFERTILITY AND ANTITUMOR MEANS
ES325827A1 (en) Procedure to produce 2-phenoxy-2-phenylacetamide compounds. (Machine-translation by Google Translate, not legally binding)
GB1131941A (en) Improvements in or relating to substituted malonic acid hydrazides
ES403910A1 (en) Imidazo-4,5-b-pyridine derivatives
CH609049A5 (en) Process for the preparation of 2-aminoimidazoles
ES423651A1 (en) Aromatic diurethanes and their use as herbicides
ES401035A1 (en) Procedure for the preparation of fungicide agents. (Machine-translation by Google Translate, not legally binding)
ES461718A1 (en) Phenoxyphenoxyalkane derivatives process for their preparation and herbicidal compositions containing them
ES461846A2 (en) A-ketocarboxamides
ES311820A1 (en) Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding)
Gersdorff et al. The Relative Toxicity to House Flies of Endrin and Isodrin in Kerosene Sprays
ES383905A1 (en) A procedure for the preparation of pyrimidopiridazine derivatives. (Machine-translation by Google Translate, not legally binding)
GB992796A (en) Improvements in or relating to c-normorphinan derivatives and their preparation
ES259491A1 (en) A procedure for the preparation of new compounds with fungicidal properties (Machine-translation by Google Translate, not legally binding)
ES412484A1 (en) Procedure for the preparation of carbostirilic derivatives. (Machine-translation by Google Translate, not legally binding)
SU809814A1 (en) DERIVATIVES 2- (2&#39;-PENTHEN-4&#39;-IL) ANILINA, EXHIBITING INHIBITIVE ACTIVITY DURING STEEL DISSOLUTION IN MINERAL ACIDS AND METHOD FOR THEIR RECOVERY
GB807548A (en) New halogen-pyridazines and process for their manufacture
ES275615A1 (en) Procedure for the preparation of a new derivative of piperacin (Machine-translation by Google Translate, not legally binding)