GB869149A - Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances - Google Patents
Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substancesInfo
- Publication number
- GB869149A GB869149A GB29595/58A GB2959558A GB869149A GB 869149 A GB869149 A GB 869149A GB 29595/58 A GB29595/58 A GB 29595/58A GB 2959558 A GB2959558 A GB 2959558A GB 869149 A GB869149 A GB 869149A
- Authority
- GB
- United Kingdom
- Prior art keywords
- resins
- resin
- acid
- groups
- registered trade
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000007788 liquid Substances 0.000 title abstract 4
- 239000003456 ion exchange resin Substances 0.000 title abstract 3
- 229920003303 ion-exchange polymer Polymers 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000000126 substance Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 229920005989 resin Polymers 0.000 abstract 7
- 239000011347 resin Substances 0.000 abstract 7
- 239000003814 drug Substances 0.000 abstract 6
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 abstract 4
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 abstract 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 4
- VIROVYVQCGLCII-UHFFFAOYSA-N amobarbital Chemical compound CC(C)CCC1(CC)C(=O)NC(=O)NC1=O VIROVYVQCGLCII-UHFFFAOYSA-N 0.000 abstract 4
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 4
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 4
- -1 aliphatic ester Chemical class 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 229940124597 therapeutic agent Drugs 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 abstract 2
- WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 abstract 2
- BWLUMTFWVZZZND-UHFFFAOYSA-N Dibenzylamine Chemical group C=1C=CC=CC=1CNCC1=CC=CC=C1 BWLUMTFWVZZZND-UHFFFAOYSA-N 0.000 abstract 2
- BHHGXPLMPWCGHP-UHFFFAOYSA-N Phenethylamine Chemical class NCCC1=CC=CC=C1 BHHGXPLMPWCGHP-UHFFFAOYSA-N 0.000 abstract 2
- 239000004793 Polystyrene Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229930013930 alkaloid Natural products 0.000 abstract 2
- 229960004909 aminosalicylic acid Drugs 0.000 abstract 2
- 229960001301 amobarbital Drugs 0.000 abstract 2
- 125000000129 anionic group Chemical group 0.000 abstract 2
- 229940125715 antihistaminic agent Drugs 0.000 abstract 2
- 239000000739 antihistaminic agent Substances 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 2
- 229920003086 cellulose ether Polymers 0.000 abstract 2
- 229960004126 codeine Drugs 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 abstract 2
- 229960002179 ephedrine Drugs 0.000 abstract 2
- 239000000796 flavoring agent Substances 0.000 abstract 2
- 235000013355 food flavoring agent Nutrition 0.000 abstract 2
- 235000003599 food sweetener Nutrition 0.000 abstract 2
- 235000011187 glycerol Nutrition 0.000 abstract 2
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 abstract 2
- 229960005181 morphine Drugs 0.000 abstract 2
- 229920002223 polystyrene Polymers 0.000 abstract 2
- 229920005990 polystyrene resin Polymers 0.000 abstract 2
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical group OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 2
- 239000003765 sweetening agent Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- FOLJTMYCYXSPFQ-CJKAUBRRSA-N [(2r,3s,4s,5r,6r)-6-[(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-(octadecanoyloxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl octadecanoate Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](COC(=O)CCCCCCCCCCCCCCCCC)O[C@@H]1O[C@@]1(COC(=O)CCCCCCCCCCCCCCCCC)[C@@H](O)[C@H](O)[C@@H](CO)O1 FOLJTMYCYXSPFQ-CJKAUBRRSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000008135 aqueous vehicle Substances 0.000 abstract 1
- 150000007656 barbituric acids Chemical class 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 150000005419 hydroxybenzoic acid derivatives Chemical class 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 150000003445 sucroses Chemical class 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29595/58A GB869149A (en) | 1958-09-16 | 1958-09-16 | Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances |
| BE582650A BE582650A (fr) | 1958-09-16 | 1959-09-14 | Produits médicaux et particulièrement préparations pharmaceutiques |
| FR804409A FR658M (enrdf_load_stackoverflow) | 1958-09-16 | 1960-08-31 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB29595/58A GB869149A (en) | 1958-09-16 | 1958-09-16 | Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB869149A true GB869149A (en) | 1961-05-31 |
Family
ID=10294021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB29595/58A Expired GB869149A (en) | 1958-09-16 | 1958-09-16 | Liquid pharmaceutical compositions comprising compounds of ion exchange resins and therapeutic substances |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE582650A (enrdf_load_stackoverflow) |
| FR (1) | FR658M (enrdf_load_stackoverflow) |
| GB (1) | GB869149A (enrdf_load_stackoverflow) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4228152A (en) * | 1974-10-15 | 1980-10-14 | Paolo Ferruti | Polymers containing prostaglandin radicals, process for their preparation and use thereof |
| DE2929456A1 (de) | 1979-07-20 | 1981-02-05 | Lentia Gmbh | Zusammensetzung mit verlaengerter broncholytischer und tokolytischer wirksamkeit, ein verfahren zu deren herstellung und broncholytisch und tokolytisch wirkendes mittel |
| GB2134529A (en) * | 1983-01-12 | 1984-08-15 | Ciba Geigy Ag | Drug-resin complex |
| US4999189A (en) * | 1988-11-14 | 1991-03-12 | Schering Corporation | Sustained release oral suspensions |
| US5186930A (en) * | 1988-11-14 | 1993-02-16 | Schering Corporation | Sustained release oral suspensions |
| US5219563A (en) * | 1988-05-11 | 1993-06-15 | Glaxo Group Limited | Drug adsorbates |
| US8232265B2 (en) | 2005-10-07 | 2012-07-31 | Board Of Trustees Of The University Of Alabama | Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients |
-
1958
- 1958-09-16 GB GB29595/58A patent/GB869149A/en not_active Expired
-
1959
- 1959-09-14 BE BE582650A patent/BE582650A/fr unknown
-
1960
- 1960-08-31 FR FR804409A patent/FR658M/fr active Active
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4228152A (en) * | 1974-10-15 | 1980-10-14 | Paolo Ferruti | Polymers containing prostaglandin radicals, process for their preparation and use thereof |
| DE2929456A1 (de) | 1979-07-20 | 1981-02-05 | Lentia Gmbh | Zusammensetzung mit verlaengerter broncholytischer und tokolytischer wirksamkeit, ein verfahren zu deren herstellung und broncholytisch und tokolytisch wirkendes mittel |
| US4344933A (en) | 1979-07-20 | 1982-08-17 | Chemie Linz Aktiengesellschaft | Pharmaceutical composition with prolonged broncholytic and tocolytic activity |
| GB2134529A (en) * | 1983-01-12 | 1984-08-15 | Ciba Geigy Ag | Drug-resin complex |
| US5219563A (en) * | 1988-05-11 | 1993-06-15 | Glaxo Group Limited | Drug adsorbates |
| US4999189A (en) * | 1988-11-14 | 1991-03-12 | Schering Corporation | Sustained release oral suspensions |
| US5186930A (en) * | 1988-11-14 | 1993-02-16 | Schering Corporation | Sustained release oral suspensions |
| US8232265B2 (en) | 2005-10-07 | 2012-07-31 | Board Of Trustees Of The University Of Alabama | Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients |
| US8802596B2 (en) | 2005-10-07 | 2014-08-12 | Board Of Trustees Of The University Of Alabama | Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients |
Also Published As
| Publication number | Publication date |
|---|---|
| FR658M (enrdf_load_stackoverflow) | 1961-07-10 |
| BE582650A (fr) | 1959-12-31 |
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