GB865675A - Improvements relating to heterocyclic nitrogen compounds and their use - Google Patents

Abstract

The invention comprises compounds of the formula: <FORM:0865675/IV (b)/1> where A is a saturated hydrocarbon radical bound to the two nitrogen atoms by a , b - or a -q -carbon atoms, R1 is a lipophilic aliphatic radical (particularly a saturated alkyl radical having 10-14 carbon atoms) and R2 is hydrogen, an alkyl radical containing 1-5 carbon atoms, or a cyclohexyl radical. The group A may be aliphatic or cycloaliphatic. These compounds may be prepared by reacting a diamine of formula R1-NH-A-NH-R2 with a cyanogen halide, advantageously in an inert organic solvent and heating if necessary and liberating the base with alkali. Lists of suitable diamines are given. In a modification, a cyanogen halide is reacted with a compound NH2-A-NH-R, where R is hydrogen or one of R1 and R2, and the other group(s) introduced by alkylation. The compounds of the invention form salts with inorganic and organic acids. The diamine starting materials may be prepared by alkylation of the primary diamines. The compounds of the invention have biocidal activity (see Groups IV(c) and VI). Reference has been directed by the Comptroller to Specification 765,547.ALSO:Textiles, e.g. blankets and restaurant and hotel linen, may be disinfected and rendered antiseptic by treatment with compositions containing a compound of formula:- <FORM:0865675/IV(c)/1> where A is a saturated hydrocarbon radical bound at the two nitrogen atoms by a , b - or a , g -carbon atoms, R1 is a lipophilic aliphatic radical (particularly a saturated alkyl radical having 10-14 carbon atoms), and R2 is hydrogen, an alkyl radical containing 1-5 carbon atoms, or a cyclohexyl radical. The compositions may be based on organic solvents, or aqueous solutions of salts of the above compounds may be used. Reference has been directed by the Comptroller to Specification 765,547.ALSO:Biocidal compositions contain as active ingredient a compound of formula <FORM:0865675/VI/1> where A is a saturated hydrocarbon radical bound at the two nitrogen atoms by a ,b - or a ,g -carbon atoms, R1 is a lipophilic aliphatic radical (particularly a saturated alkyl radical having 10-14 carbon atoms), and R2 is hydrogen, an alkyl radical containing 1-5 carbon atoms, or a cyclohexyl radical. The compounds may be used in solution or dispersion, and the compositions may contain inert carriers or fillers, cleansers, ointment bases, creams and other fungicidal and bactericidal agents. They may be used in cosmetic preparations as ointments and creams. They have fungicidal or fungistatic, bactericidal and algaecidal activity. Reference has been directed by the Comptroller to Specification 765,547.